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    LIGHT-WAND AND BALLOON CATHETERS
    11.
    发明申请
    LIGHT-WAND AND BALLOON CATHETERS 审中-公开
    光束和气球导管

    公开(公告)号：WO2008066943A3

    公开(公告)日：2008-12-18

    申请号：PCT/US2007067045

    申请日：2007-04-20

    Applicant: LUMERX INC ,  LEVIN PHILIP ,  KAZLAS PETER ,  SINOFSKY EDWARD L ,  EVANS STEPHEN P ,  GUILES MARVIN ,  GONCALVES DAVID P ,  TOLKOFF MARC J ,  CERIER JEFFREY C ,  ABRAHAM RICHARD

    Inventor： LEVIN PHILIP ,  KAZLAS PETER ,  SINOFSKY EDWARD L ,  EVANS STEPHEN P ,  GUILES MARVIN ,  GONCALVES DAVID P ,  TOLKOFF MARC J ,  CERIER JEFFREY C ,  ABRAHAM RICHARD

    IPC: A61B18/24

    CPC classification number: A61N5/0603 ,  A61N2005/0609 ,  A61N2005/0652 ,  A61N2005/0654

    Abstract: One aspect of the invention relates to an apparatus which has a light emitting portion for directing light radiation from the apparatus onto the lining of a body cavity for treating an ailment in a body cavity of a patient. For example, the ailment may be a gastrointestinal ailment of a patient, such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease. The apparatus may also be used for treating diseases of the circulatory system, urogenital systems and other body cavities. In one embodiment, the apparatus is inserted into a body cavity, e.g., stomach or colon, of the patient to place the distal tip of the apparatus in the desired position. A balloon is then inflated around the light-emitting portion of the apparatus, e.g., an array of optical fiber ends. The body cavity of the patient is then irradiated with light radiation so as to kill or debilitate microorganisms lining the body cavity without significant destruction of the body tissue of the patient, thereby improving or alleviating one or more of the symptoms associated with the ailment. Following treatment, a probiotic may be administered to the patient to reestablish the growth of normal microbial flora after treatment of the gastrointestinal tract.

    Abstract translation: 本发明的一个方面涉及一种设备，其具有用于将来自设备的光辐射引导到体腔的衬里上用于治疗患者体腔中的疾病的发光部分。 例如，疾病可以是患者的胃肠疾病，例如胃炎，胃溃疡，十二指肠溃疡，胃癌，胃淋巴瘤，溃疡性结肠炎或克罗恩氏病。 该装置也可用于治疗循环系统疾病，泌尿生殖系统和其他体腔疾病。 在一个实施例中，该设备被插入到患者的体腔（例如胃或结肠）中，以将该设备的远端放置在期望的位置。 然后在装置的发光部分（例如光纤端部阵列）周围充气。 然后用光辐射照射患者的体腔，从而杀死或减弱衬在体腔内的微生物而不显着破坏患者的身体组织，从而改善或减轻与疾病相关的一种或多种症状。 在治疗之后，可以给患者施用益生菌以在治疗胃肠道后重建正常微生物菌群的生长。

    LIGHT-WAND AND BALLOON CATHETERS
    12.
    发明申请
    LIGHT-WAND AND BALLOON CATHETERS 审中-公开
    轻型和气球导管

    公开(公告)号：WO2008066943A2

    公开(公告)日：2008-06-05

    申请号：PCT/US2007/067045

    申请日：2007-04-20

    Applicant: LUMERX, INC. ,  LEVIN, Philip ,  KAZLAS, Peter ,  SINOFSKY, Edward, L. ,  EVANS, Stephen, P. ,  GUILES, Marvin ,  GONCALVES, David, P. ,  TOLKOFF, Marc, J. ,  CERIER, Jeffrey, C. ,  ABRAHAM, Richard

    Inventor： LEVIN, Philip ,  KAZLAS, Peter ,  SINOFSKY, Edward, L. ,  EVANS, Stephen, P. ,  GUILES, Marvin ,  GONCALVES, David, P. ,  TOLKOFF, Marc, J. ,  CERIER, Jeffrey, C. ,  ABRAHAM, Richard

    IPC: A61B1/01

    CPC classification number: A61N5/0603 ,  A61N2005/0609 ,  A61N2005/0652 ,  A61N2005/0654

    Abstract: One aspect of the invention relates to an apparatus which has a light emitting portion for directing light radiation from the apparatus onto the lining of a body cavity for treating an ailment in a body cavity of a patient. For example, the ailment may be a gastrointestinal ailment of a patient, such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease. The apparatus may also be used for treating diseases of the circulatory system, urogenital systems and other body cavities. In one embodiment, the apparatus is inserted into a body cavity, e.g. , stomach or colon, of the patient to place the distal tip of the apparatus in the desired position. A balloon is then inflated around the light-emitting portion of the apparatus, e.g. , an array of optical fiber ends. The body cavity of the patient is then irradiated with light radiation so as to kill or debilitate microorganisms lining the body cavity without significant destruction of the body tissue of the patient, thereby improving or alleviating one or more of the symptoms associated with the ailment. Following treatment, a probiotic may be administered to the patient to reestablish the growth of normal microbial flora after treatment of the gastrointestinal tract.

    Abstract translation: 本发明的一个方面涉及一种装置，其具有发光部分，用于将来自该装置的光辐射引导到体腔的衬里上，用于治疗患者体腔内的疾病。 例如，疾病可能是患者的胃肠道疾病，例如胃炎，胃溃疡，十二指肠溃疡，胃癌，胃淋巴瘤，溃疡性结肠炎或克罗恩氏病。 该装置还可用于治疗循环系统，泌尿生殖系统和其它体腔的疾病。 在一个实施例中，将该装置插入到患者的体腔（例如胃或结肠）中，以使装置的远侧末端处于所需位置。 然后气球围绕设备的发光部分充气，例如光纤端部阵列。 然后用光辐射照射患者的体腔，以便杀死或破坏体腔内的微生物，而不会显着破坏患者的身体组织，从而改善或减轻与疾病相关的一种或多种症状。 在治疗后，可以向患者施用益生菌以在治疗胃肠道之后重新建立正常微生物菌群的生长。

    A TOOTHPICK FOR LIGHT TREATMENT OF BODY STRUCTURES
    16.
    发明申请
    A TOOTHPICK FOR LIGHT TREATMENT OF BODY STRUCTURES 审中-公开
    一种用于轻体治疗身体结构的牙膏

    公开(公告)号：WO2005018475A2

    公开(公告)日：2005-03-03

    申请号：PCT/US2004/026201

    申请日：2004-08-11

    Applicant: ORALUM LLC

    Inventor： BLACK, Michael

    IPC: A61C

    CPC classification number: A61N5/0603 ,  A61C15/02 ,  A61N2005/0606 ,  A61N2005/0609 ,  A61N2005/063 ,  A61N2005/0644 ,  A61N2005/0651 ,  A61N2005/067

    Abstract: A toothpick for the application of light treatment at a body structure is provided. The toothpick distinguishes a handle and an element. The handle hosts one or more light sources each capable of delivering a light beam with a unique light treatment. The element is optically connected to the light source(s) such that the light beam(s) could radiate through the surface of the element at a body structure. This radiation is not limited to radiation through the tip of the element, but would radiate in multiple directions. The element of the toothpick could be used in direct or not in direct contact with a body surface as long as the light treatment can be applied to the body structure. In case the element is in contact with a body structure, then the element could add a massaging effect to the body structure.

    Abstract translation: 提供了一种用于在身体结构处进行光处理的牙签。 牙签区分手柄和元件。 手柄托管一个或多个光源，每个光源能够以独特的光处理传递光束。 元件光学连接到光源，使得光束可以以身体结构辐射穿过元件的表面。 该辐射不限于穿过元件尖端的辐射，而是会在多个方向辐射。 牙签的元件可以直接使用或不直接与身体表面接触，只要可以将光处理应用于身体结构。 在元件与身体结构接触的情况下，该元件可以向身体结构添加按摩效果。

    DEVICE FOR IRRADIATING INTERNAL CAVITIES OF THE BODY
    18.
    发明申请
    DEVICE FOR IRRADIATING INTERNAL CAVITIES OF THE BODY 审中-公开
    用于照射身体内部空间的装置

    公开(公告)号：WO99011322A1

    公开(公告)日：1999-03-11

    申请号：PCT/CH1998/000370

    申请日：1998-08-28

    IPC: A61B18/22 ,  A61N5/06

    CPC classification number: A61N5/0603 ,  A61B2018/2261 ,  A61N2005/0609 ,  A61N2005/0611

    Abstract: The invention concerns a device (100) for irradiating internal cavities of the body comprising a flexible catheter (11), made of transparent material, containing an optical fibre (13) whereof an end section (18) is arranged for radially diffusing light derived from a source provided at the fibre other end, and an inflatable balloon (140) fixed at one end of the catheter so as to cover the optical fibre (13) diffusing section (13). The balloon (140) is made of elastomer material partially diffusing light and prefabricated by moulding of a specific print of the cavity to be treated, so as to match its form. It is properly pressed against the cavity wall, the thickness of the wall remains constant after the balloon has been inflated, and the pressure required for said inflating is low and cannot damage the cavity tissues.

    Abstract translation: 本发明涉及用于照射身体的内部空腔的装置（100），其包括由透明材料制成的柔性导管（11），其包含光纤（13），其中端部部分（18）被布置用于径向扩散源自 设置在纤维另一端的源和固​​定在导管的一端以覆盖光纤（13）扩散部分（13）的可充气气囊（140）。 气球（140）由弹性体材料制成，部分地漫射光，并通过模制待处理的腔的特定印刷而预制，以便匹配其形状。 它被适当地压在空腔壁上，气囊膨胀后壁的厚度保持恒定，并且所述充气所需的压力低并且不能损伤空腔组织。

    PHOTOCHEMICAL ABLATION OF GASTRO-INTESTINAL TISSUE
    19.
    发明申请
    PHOTOCHEMICAL ABLATION OF GASTRO-INTESTINAL TISSUE 审中-公开
    胃肠组织的光化学吸收

    公开(公告)号：WO1995019735A1

    公开(公告)日：1995-07-27

    申请号：PCT/US1995000359

    申请日：1995-01-11

    Applicant: MEDICAL COLLEGE OF OHIO

    Inventor： MEDICAL COLLEGE OF OHIO ,  SELMAN, Steven, H. ,  KROPP, Kenneth, A. ,  HASELHUHN, Gregory, D.

    IPC: A61B17/00

    CPC classification number: A61N5/062 ,  A61B17/00 ,  A61B18/20 ,  A61B18/22 ,  A61N5/0601 ,  A61N2005/0609 ,  A61N2005/061

    Abstract: A method for treating a human or animal patient amenable to organ augmentation with gastro-intestinal tissue (30) which is, or will be, surgically transplanted into the patient's organ. The gastro-intestinal tissue (30) is sensitized with an effective amount of a photosensitive composition. The sensitized tissue is exposed to a source of electromagnetic radiation energy (28) for a predetermined time, wavelength and intensity sufficient to cause cellular and/or mucosal tissue function of the sensitized tissue to diminish or cease.

    Abstract translation: 一种用于或将手术移植到患者器官中的胃肠组织（30）治疗适于增加器官的人或动物患者的方法。 胃肠组织（30）用有效量的光敏组合物敏化。 致敏组织暴露于电磁辐射能量（28）的预定时间，足以使致敏组织的细胞和/或粘膜组织功能减弱或停止的波长和强度。

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