公开(公告)号：WO2013188389A1

公开(公告)日：2013-12-19

申请号：PCT/US2013/045162

申请日：2013-06-11

Applicant: GENERAL ELECTRIC COMPANY

Inventor： ZHU, Li ,  PULEO, Christopher Michael ,  GODIN, Jessica Marie

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2200/04 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2200/14 ,  B01L2200/16 ,  B01L2300/087 ,  B01L2400/043 ,  B01L2400/0481 ,  B01L2400/0655 ,  Y10T436/25375

Abstract: A microfluidic system for preparing a sample containing an analyte of interest is provided. The microfluidic system includes a microfluidic cartridge and a magnetic element. The microfluidic cartridge includes a number of reservoirs, an immobilizer, a number of microfluidic flow channels and a number of microvalves. The microfluidic channels are coupled with the reservoirs and the immobilizer. The microvalves are positioned along the microfluidic flow channels. The magnetic element is positioned with respect to the immobilizer. The magnetic element is configured to generate a magnetic field to magnetically immobilize the analyte of interest in the immobilizer. The immobilizer is configured to flow one or more reagents therethrough to react with the analyte of interest.

Abstract translation: 提供了一种用于制备含有感兴趣分析物的样品的微流体系统。 微流体系统包括微流体盒和磁性元件。 微流控盒包括多个储存器，防盗器，多个微流体流动通道和多个微型阀。 微流体通道与储存器和防盗器结合。 微阀沿着微流体流动通道定位。 磁性元件相对于防盗器定位。 磁性元件被配置成产生磁场以将感兴趣的分析物磁性地固定在防盗器中。 防盗器构造成使一种或多种试剂流过其中以与感兴趣的分析物反应。