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    AN INTERFACE COMPONENT FOR A MICROFLUIDIC DEVICE, ASSEMBLIES, AND METHOD FOR EXTRACTING PARTICLES FROM A SAMPLE
    4.
    发明申请
    AN INTERFACE COMPONENT FOR A MICROFLUIDIC DEVICE, ASSEMBLIES, AND METHOD FOR EXTRACTING PARTICLES FROM A SAMPLE 审中-公开
    用于微流体装置的接口组件，组件和从样品中提取颗粒的方法

    公开(公告)号：WO2017093781A1

    公开(公告)日：2017-06-08

    申请号：PCT/IB2015/059220

    申请日：2015-11-30

    Applicant: RQMICRO AG

    Inventor： SCHAFFHAUSER, Daniel

    IPC: B01L3/00

    CPC classification number: B01L3/502715 ,  B01L3/50273 ,  B01L2200/027 ,  B01L2300/0681 ,  B01L2300/14 ,  B01L2400/0478 ,  B01L2400/0487 ,  B01L2400/0655 ,  B01L2400/082

    Abstract: An interface component (40), suitable for cooperating with a microfluidic device (1), the interface component comprising, one or more elements (41) which can be selectively connected to a pneumatic system (71 a,71 b) which can provide a positive and/or negative air flow to the one or more elements (41); wherein each of the one or more elements (41) comprises, an input port (42) which can be selectively fluidly connected to a pneumatic system (71 a,71 b); and a flow restrictor (43) according to a further aspect of the present invention; the flow restrictor (43) being arranged in fluid communication with the input port (42), wherein the flow restrictor (43) can restrict the flow of fluid through the element (41); and an aerosol filter (49) which is arranged to be in fluid communication with the flow restrictor (43); and wherein the interface component (40) further comprises one or more outlets (45), each of the one or more outlets (45) being in fluid communication with a respective element (41), so that fluid can flow from the element (41) out of the interface component (40) via the one or more outlets (45); and wherein each of the one or more outlets (45) can be selectively arranged to be in fluid communication with a respective reservoir (105,106,107,108) of a microfluidic device (1). There is further provided a corresponding method and assembly for extracting ferromagnetic, paramagnetic and/or diamagnetic particles from a sample.

    Abstract translation: 适于与微流体装置（1）配合的接口部件（40），所述接口部件包括一个或多个可选择性地连接到气动系统（71a）的元件（41） ，71b），其可以向所述一个或多个元件（41）提供正和/或负空气流; 其中所述一个或多个元件（41）中的每一个包括可选择性地流体连接至气动系统（71a，71b）的输入端口（42）; 和根据本发明的另一方面的限流器（43） 所述限流器（43）布置成与所述输入端口（42）流体连通，其中所述限流器（43）能够限制通过所述元件（41）的流体流动。 和布置成与限流器（43）流体连通的气溶胶过滤器（49）; 并且其中所述界面部件（40）还包括一个或多个出口（45），所述一个或多个出口（45）中的每一个与相应的元件（41）流体连通，使得流体可以从所述元件（41 ）通过所述一个或多个出口（45）流出所述界面部件（40）; 并且其中所述一个或多个出口（45）中的每一个可被选择性地布置成与微流体装置（1）的相应贮存器（105,106,107,108）流体连通。 还提供了用于从样品中提取铁磁性，顺磁性和/或反磁性颗粒的相应方法和组件。

    MICROFLUIDIC DEVICE AND METHOD FOR BATCH ADSORPTION
    8.
    发明申请
    MICROFLUIDIC DEVICE AND METHOD FOR BATCH ADSORPTION 审中-公开
    微流量装置和批量吸附方法

    公开(公告)号：WO2016207320A1

    公开(公告)日：2016-12-29

    申请号：PCT/EP2016/064621

    申请日：2016-06-23

    Applicant: UNIVERSITEIT TWENTE ,  TECHNISCHE UNIVERSITEIT DELFT

    Inventor： RHO, Hoon Suk ,  GARDENIERS, Johannes Gerardus Elisabeth ,  OTTENS, Marcel ,  HANKE, Alexander Thomas

    IPC: F16K99/00 ,  G01N30/60 ,  B01L3/00

    CPC classification number: B01L3/502761 ,  B01L3/502738 ,  B01L3/502746 ,  B01L2200/0668 ,  B01L2300/0864 ,  B01L2300/123 ,  B01L2400/0622 ,  B01L2400/0655 ,  B01L2400/082 ,  B01L2400/086 ,  F16K99/0026 ,  F16K99/0055 ,  G01N30/56 ,  G01N30/603 ,  G01N30/6095

    Abstract: The invention relates to a fluidic device (1) having a particle trap functionality for a particle (2) in a fluid, the fluidic device (1) comprising a first fluid flow channel (11), a second fluid flow channel (12), and a control channel (13), wherein the first fluid flow channel (11) is in fluid contact with the second fluid flow channel (12) and intersects the second fluid flow channel (12) at an intersection (14), wherein the control channel (13) at the location of the intersection (14) is arranged adjacent to the first fluid flow channel (11) and separated by a flexible membrane (17) from the intersection (14), wherein the flexible membrane (17) is configured as a valve (31), configured in operation at a first pressure in the control channel (13) in a first position not to block propagation of a particle (2) of a predetermined size in the first fluid flow channel (11), and at a second pressure in the control channel (13) in a second position to block with said flexible membrane (17) propagation of said particle (2) through the first fluid flow channel (11), while in this second position not fully blocking fluid flow through the first fluid flow channel (11) wherein the valve (31) is configured to provide in said second position a gradual increasing blockade of a cross sectional area (19) of the first fluid flow channel (11) in a direction parallel to a longitudinal axis of the first fluid flow channel (11).

    Abstract translation: 本发明涉及一种具有用于流体中的颗粒（2）的颗粒捕集功能的流体装置（1），该流体装置（1）包括第一流体流动通道（11），第二流体流动通道（12） 和控制通道（13），其中所述第一流体流动通道（11）与所述第二流体流动通道（12）流体接触并且在交叉点（14）处与所述第二流体流动通道（12）相交，其中所述控制 在交叉点（14）的位置处的通道（13）布置成与第一流体流动通道（11）相邻并且由柔性膜（17）与交叉点（14）分离，其中柔性膜（17）被配置 作为阀（31），其在第一位置中以控制通道（13）中的第一压力操作而不在第一流体通道（11）中阻挡预定尺寸的颗粒（2）的传播的第一位置，以及 在所述控制通道（13）中的第二压力处于与所述柔性膜（17）阻挡的第二位置， 所述颗粒（2）通过第一流体流动通道（11）的传播，而在该第二位置，不完全阻止流过第一流体流动通道（11）的流体，其中阀（31）构造成提供在所述第二位置 第一流体流动通道（11）的横截面积（19）在平行于第一流体流动通道（11）的纵向轴线的方向上逐渐增加。

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