Abstract:
A compound (a) having at least two oxetane rings per molecule is reacted with a compound (b) having at least two carboxyl groups per molecule and an unsaturated monocarboxylic acid (c) in the presence of an accelerator in such a proportion that the molar ratio of the compound (b) to the compound (a) is in the range of 0.1
Abstract:
Poly(ethylene glycol) (PEG), a highly biocompatible hydrophilic polyether, is tethered to poly(propylene fumarate) (PPF), a biodegradable polyester. To avoid change in molecular weight distribution of PPF, end hydroxyl groups of PPF are reacted with bis-carboxymethyl PEG after being treated with thionyl chloride. New end carboxyl groups of the PEG-tethered PPF are further reacted with N-hydroxysuccinimide (NHS) in the presence of dicyclohexylcarbodiimide (DCC) to couple bioactive molecules. Glutamine and glycine-arginine-glycine-aspartic acid (GRGD) are attached to the PEG-tethered PPF in 50 mM phosphate buffer of pH of 7.4. The method is valuable for the preparation of a triblock copolymer with PEG end blocks and the coupling of biologically active molecules.
Abstract:
A general approach to making water-resistance polyetherester resins and thermosets is disclosed. In one aspect, an unsaturated polyetherester resin prepared by inserting a carboxylic acid derivative into a polyether is co-cured with a vinyl monomer and a di- or polyisocyanate to give a water-resistant, thermoset that has excellent dimensional stability, flexibility, and strength properties. Processes for making low-viscosity resins that give thermosets with good water resistance are also described. In one process, an unsaturated polyetherester resin intermediate reacts with a mono-functional isocyanate or fatty alcohol to produce an easy-to-formulate, low-viscosity, low-molecular-weight capped resin.
Abstract:
A composition comprising the reaction product of: a) a polycarboxylic member selected from the group consisting of polycarboxylic acids comprised of a diacid having more than about 12 carbon atoms and reactive derivatives thereof (e.g. alkyl esters thereof wherein the alkyl group has from 1 to 4 carbon atoms), b) an ethylenically unsaturated member selected from the group consisting of ethylenically unsaturated mono-carboxylic acids and reactive derivatives thereof, (e.g. alkyl esters thereof wherein the alkyl group thereof has from 1 to 4 carbon atoms), and c) an ethoxylated alkanetriol having an average degree of ethoxylation per hydroxyl of less than about 2 and comprised predominantly of ethoxylated alkanetriol species having one ethoxylaate group per hydroxyl. This composition is useful as a polymerizable component, particularly for UV curable coatings and inks.
Abstract:
The invention relates to novel crosslinkable prepolymers comprising structural units of formula (1) wherein the variables are as defined in the claims, to crosslinked polymers, to either homo-polymers or co-polymers prepared from those novel prepolymers, to mouldings produced from the said homo- or co-polymers, and especially to contact lenses produced from those homo- or co-polymers.
Abstract:
Vinyl ether terminated ester oligomers having a range of molecular weights are prepared by reacting a vinyl ether terminated polybasic ester with a polyol in the presence of a catalyst. Continual removal of a hydroxy monovinyl ether avoids formation compounds containing acetal moieties. Alternatively, a polybasic ester is chain extended with a polyol with continual removal of the alcohol by-product. Then, the terminal ester moieties are end capped with a monohydroxy vinyl ether. The oligomers have application in coatings and the like.
Abstract:
An amphiphilic polymer, having the monomer unit structure (A), (B), (C) or (D) wherein R is at least one of H and C1-6 alkyl, k = 1-4, m = 4-30, n = 2-50, and x = 2-500; (B) and (C) wherein p and q are, independently, 0-22, and the sum of p and q is 4-44; (D) wherein r and s are, independently, 0-22, and the sum of r and s is in the range 2-44, Ar is a divalent aromatic radical; and compounds in which the ester group in compounds (A), (B), (C) and (D) is replaced by an amide, urea, urethane, ether, or carbonate. These compounds are useful for disrupting lipid membranes, as surfactants and dispersing agents and in the treatment of viral, bacterial and fungal diseases.
Abstract:
The present disclosure provides a polymer having a repeating unit comprising at least one astaxanthin moiety, including processes for its preparation and various uses thereof.
Abstract:
Disclosed herein is a crosslinkable polyketal ester obtained by the esterification of a hydrocarbon polyol by at least 2 equivalents of a ketocarboxylic acid to produce an intermediate polyketocarboxylic ester. The intermediate polyketocarboxylic ester is then ketalized to produce the crosslinkable polyketal ester, which can then be used in compositions or crosslinked.
Abstract:
Provided herein are compositions, devices, and systems comprising thermoresponsive, biodegradable elastomeric materials, and methods of use and manufacture thereof.