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    SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES
    31.
    发明申请
    SMART POLYMER MATERIALS WITH EXCESS REACTIVE MOLECULES 审中-公开
    具有超强反应性分子的SMART聚合物材料

    公开(公告)号：WO2013138524A1

    公开(公告)日：2013-09-19

    申请号：PCT/US2013/031062

    申请日：2013-03-13

    Applicant: MEDIPACS, INC. ,  THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

    Inventor： BANISTER, Mark ,  GERONOV, Yordan ,  MCGRATH, Dominic

    IPC: C08G65/00 ,  C08L63/10 ,  C08L65/00

    CPC classification number: C08G65/2624 ,  C08G59/22 ,  C08G59/504 ,  C08G83/004 ,  C08G2650/50 ,  C08L63/00 ,  C08L67/00

    Abstract: A three-dimensional smart polymer matrix is formed by a first epoxy chemical reaction linking a linear polymer chain and a branched polymer chain, wherein the polymer chains are flexible and one or more reactive molecule species remain unreacted, at a predetennined mathematical ratio of reacted to un-reacted molecules and molecule species, and the un-reacted molecular species are available for further chemical reaction, protonation or deprotonation after the first chemical reaction. The resulting smart polymer matrix is hydrophilic and non-soluble to a solvent or electrolyte.

    Abstract translation: 通过连接线性聚合物链和支链聚合物链的第一环氧化学反应形成三维智能聚合物基质，其中聚合物链是柔性的并且一个或多个反应性分子物质保持未反应，以预定的数学比率反应 未反应的分子和分子物质，未反应的分子物质可用于在第一次化学反应后进一步的化学反应，质子化或去质子化。 所得的智能聚合物基质是亲水的并且不溶于溶剂或电解质。

    GRAFT COPOLYMERS OF A POLY(VINYLIDENE FLUORIDE)-BASED POLYMER AND AT LEAST ONE TYPE OF ELECTRICALLY CONDUCTIVE POLYMER, AND METHODS FOR FORMING THE GRAFT COPOLYMERS
    32.
    发明申请
    GRAFT COPOLYMERS OF A POLY(VINYLIDENE FLUORIDE)-BASED POLYMER AND AT LEAST ONE TYPE OF ELECTRICALLY CONDUCTIVE POLYMER, AND METHODS FOR FORMING THE GRAFT COPOLYMERS 审中-公开
    聚（氟乙烯）共聚物和至少一种导电聚合物类型的共聚物和形成共聚物的方法

    公开(公告)号：WO2013085467A1

    公开(公告)日：2013-06-13

    申请号：PCT/SG2012/000461

    申请日：2012-12-07

    Applicant: NANYANG TECHNOLOGICAL UNIVERSITY

    Inventor： LEE, Pooi See ,  KUMAR, Vijay ,  LIN, Meng-Fang

    IPC: C08F259/08 ,  C08F291/18 ,  C08L27/16

    CPC classification number: C08J3/28 ,  C08F8/30 ,  C08F214/22 ,  C08F214/245 ,  C08G73/0266 ,  C08G81/024 ,  C08G83/004 ,  C08J2327/16 ,  C08L101/005 ,  C09D187/005 ,  H01B3/303 ,  H01B3/445 ,  H01G4/14 ,  H01G4/30 ,  H01G4/306

    Abstract: Methods for forming a graft copolymer of a poly(vinylidene fluoride)-based polymer and at least one type of electrically conductive polymer, wherein the electrically conductive polymer is grafted on the poly(vinylidene fluoride)-based polymer are provided. The methods comprise a) irradiating a poly(vinylidene fluoride)-based polymer with a stream of electrically charged particles; b) forming a solution comprising the irradiated poly(vinylidene fluoride)-based polymer, an electrically conductive monomer and an acid in a suitable solvent; and c) adding an oxidant to the solution to form the graft copolymer. Graft copolymers of a poly(vinylidene fluoride)-based polymer and at least one type of electrically conductive polymer, wherein the electrically conductive polymer is grafted on the poly(vinylidene fluoride)-based polymer, nanocomposite materials comprising the graft copolymer, and multilayer capacitors comprising the nanocomposite material are also provided.

    Abstract translation: 提供了聚偏二氟乙烯基聚合物与至少一种导电聚合物的接枝共聚物的形成方法，其中导电聚合物接枝在聚（偏二氟乙烯）基聚合物上。 所述方法包括：a）用带电粒子的流照射聚（偏二氟乙烯）基聚合物; b）在合适的溶剂中形成包含被照射的聚偏二氟乙烯基聚合物，导电单体和酸的溶液; 和c）向溶液中加入氧化剂以形成接枝共聚物。 聚偏二氟乙烯基聚合物与至少一种类型的导电聚合物的接枝共聚物，其中导电聚合物接枝在聚（偏二氟乙烯）基聚合物上，包含接枝共聚物的纳米复合材料和多层电容器 也提供了纳米复合材料。

    HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME
    35.
    发明申请
    HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME 审中-公开
    高度氟化油和表面活性剂及其制备方法和使用方法

    公开(公告)号：WO2007112100A3

    公开(公告)日：2007-12-21

    申请号：PCT/US2007007459

    申请日：2007-03-26

    Applicant: UNIV UTAH RES FOUND ,  YU YIHUA ,  JIANG ZHONG-XING

    Inventor： YU YIHUA ,  JIANG ZHONG-XING

    IPC: A61B5/055 ,  C07C43/12

    CPC classification number: A61K51/065 ,  A61K41/0038 ,  A61K47/6905 ,  A61K47/6953 ,  A61K49/0002 ,  A61K49/085 ,  A61K49/124 ,  A61K49/14 ,  A61K49/1809 ,  A61K49/1818 ,  A61K51/122 ,  B82Y5/00 ,  C08G83/003 ,  C08G83/004

    Abstract: Disclosed are compounds comprising the structure (I): In one aspect, the compounds exhibit maximum symmetric branching. Also disclosed are bilayers, micelles, coatings, and nanoparticles comprising the disclosed compounds. Also disclosed are processes for the preparation of the disclosed compounds and methods of using the disclosed compounds. Also disclosed are highly fluorinated dendrons and methods for making same. Also disclosed are methods for Fluorous Mixture Synthesis and tagging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    Abstract translation: 公开了包含结构（I）的化合物：一方面，化合物表现出最大对称支化。 还公开了包含所公开的化合物的双层，胶束，涂层和纳米颗粒。 还公开了制备所公开的化合物的方法和使用所公开的化合物的方法。 还公开了高度氟化的树枝状体及其制造方法。 还公开了氟混合物合成和标记的方法。 该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

    TARGETED TRANSFECTION OF CELLS USING A BIOTINYLATED DENDRIMER
    36.
    发明申请
    TARGETED TRANSFECTION OF CELLS USING A BIOTINYLATED DENDRIMER 审中-公开
    生物素化的树枝状细胞有针对性的转染

    公开(公告)号：WO0176633A2

    公开(公告)日：2001-10-18

    申请号：PCT/EP0103746

    申请日：2001-04-03

    Applicant: QIAGEN GMBH ,  WEBER MARTIN ,  DENNIG JOERG ,  ERBACHER CHRISTOPH

    Inventor： WEBER MARTIN ,  DENNIG JOERG ,  ERBACHER CHRISTOPH

    IPC: A61K47/48 ,  C12N15/87 ,  A61K47/00

    CPC classification number: B82Y5/00 ,  A61K47/645 ,  A61K47/6898 ,  C08G83/004 ,  C12N15/87

    Abstract: The invention relates to a method for carrying out the targeted transfection of cells, to compositions, which can be used for such methods, and to corresponding medicaments for use in gene therapy. The invention particularly relates to a method for introducing nucleic acid into cells involving the following steps: (a) mixing a nucleic acid with a dendrimer, whereby a portion of the dendrimer molecules is biotinylated; mixing the prepared complex, which consists of a nucleic acid and a dendrimer, with a second complex, which consists of an avidin or a streptavidin and of a biotinylated target-specific binding molecule, and; (c) incubating the complex prepared in step (b) with cells. Dendrimers that are well-suited for the invention are, for example, partially solvolyzed polyamidoamine (PAMAM) dendrimers. Target-specific binding molecules are, in particular, cell type-specific markers also of the cell surface of the target cells.

    Abstract translation: 本发明涉及一种用于细胞的靶向的转染方法，一种能够被用于这样的程序，以及用于基因治疗的相应的药物组合物。 特别地，本发明涉及一种用于将核酸导入包括以下步骤的细胞：（a）混合核酸与树枝状聚合物，其特征在于树枝状聚合物分子的比例是生物素化; （B）混合所得的核酸和树枝状聚合物用由抗生物素蛋白或链霉亲和生物素化的靶标特异性结合分子的第二复合物的复合物; 和（c）在步骤（b）温育的细胞所得到的复合物。 例如部分solvolysierte是聚酰胺胺（PAMAM）树枝状聚合物，本发明非常适合于树枝状聚合物。 靶特异性结合分子是特定细胞类型特异性标志物和靶细胞的细胞表面。

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