Abstract:
Articles of manufacturing comprising electrospun elements having continuous or stepwise gradients of porosity, average pore size, weight per volume and/or of agents for promoting cell colonization, differentiation, extravasation and/or migration are provided. Also provided are methods of manufacturing and using same for guiding tissue regeneration.
Abstract:
Methods of generating and expanding proliferative, multipotent connective tissue progenitor cells from adult stem cells are provided. Also provided are methods of generating functional tendon grafts in vitro and bone, cartilage and connective tissues in vivo using the isolated cell preparation of connective tissue progenitor cells.
Abstract:
An apparatus for all-optical deflection of an incident optical signal beam, the apparatus comprising: a photorefractive semiconductor crystal; and an electric field source, for applying an electric field across the crystal either through electrodes or by positioning the crystal at a place where an electric field is present.. In another embodiment of the invention a second optical beam source, for illuminating the crystal with a background optical beam. The apparatus is used for steering the signal beam, lensing it or for other applications.
Abstract:
A device for improved vision into or out of at least one eye of a subject. The device comprises an enclosing vessel for holding one or more lenses in front one or two eyes of the subject and for holding a substance whose refractive index is matched to the refractive index of the cornea. The vessel is adapted to seal the substance to the face around the eye or eyes of the subject thereby allowing focusing into or out of the eye or eyes.
Abstract:
A recombinant isolated antibody and a pharmaceutical composition containing same, capable of specifically recognizing an MHC-peptide complex with an affinity in a nanomolar range and of inducing apoptosis in cancer or pathogen infected cells is provided. Also provided are method for treating and diagnosing cancer or pathogen infection in a subject using the recombinant isolated antibody of the present invention.
Abstract:
A CMOS integrated circuit for multi-channel neuronal recording with twelve true-differential channels, band separation and digital offset calibration. The recorded signal is separated into 2 bands: a low-frequency, local field potential (LFP); and high-frequency spike data. Digitally programmable gains for the LFP and spike bands are provided. A mixed-signal front-end processor for multi-channel neuronal recording is also described. It receives twelve differential-input channels of implanted recording electrodes. A programmable cutoff HPF blocks DC and low frequency input drift at about 1 Hz. The signals are band-split at about 200 Hz to low-frequency local field potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF. The analog signals are converted into digital form, and streamed out over a serial digital bus at up to 8 Mbps. A special interface system incorporating an embedded CPU core in a programmable logic device accompanied by real-time software allows connectivity to a computer host.
Abstract:
A novel group of aminoglycosides which share some structural features of currently available aminoglycosides with regard to the backbone, while also having significant structural differences. The similarity enables these aminoglycosides to be highly potent and effective antibiotics, while the significant differences enable these aminoglycosides to reduce or even block antibiotic resistance.
Abstract:
The invention relates to a core-alloyed shell semiconductor nanocrystal comprising: (i) a core of a semiconductor material having a selected band gap energy; (ii) a core-overcoating shell consisting of one or more layers comprised of an alloy of the said semiconductor of (i) and a second semiconductor; (iii) and an outer organic ligand layer, provided that the core semiconductor material is not HgTe. Preferably, the core semiconductor material is PbSe and the alloy shell semiconductor material has the PbSexS1-x structure.
Abstract:
Apparatus for analyzing light having at least one wavelength, the apparatus having a light deflector (12) for deflecting the light to provide a deflected light beam characterized by at least one wavelength dependent angle corresponding to the at least one wavelength of light, and encoder (20) capable of encoding the deflected light beam so as to provide an encoded light beam charaterized by at least one angle dependent polarization state corresponding to the at least one wavelength-dependent angle; and a decoder (24) for decoding the encoded light beam to determine at least one spectral component of the light.
Abstract:
A thermoelastically actuated microresonator device comprising: a main body (14) having a cantilevered beam (12); a heating element (20) located adjacent a surface of the cantilevered beam and adjacent the main body, that may be periodically actuated to generate a periodic heat gradient across a height of the beam, thereby facilitating periodic deflection of the beam.