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    NON-VIRULENT PORPHYROMONAS GINGIVALIS MUTANT
    42.
    发明申请
    NON-VIRULENT PORPHYROMONAS GINGIVALIS MUTANT 审中-公开
    非虚ENT。。。。。。。

    公开(公告)号：WO0009156A9

    公开(公告)日：2001-03-22

    申请号：PCT/US9918197

    申请日：1999-08-11

    Applicant: UNIV LOMA LINDA ,  FLETCHER HANSEL M

    Inventor： FLETCHER HANSEL M

    IPC: A61P1/02 ,  A61P31/04 ,  C07K14/195 ,  A61K39/02 ,  A01N63/00 ,  A61K39/00

    CPC classification number: A61K39/0216 ,  A61K2039/522 ,  C07K14/195

    Abstract: A non-virulent, recA defective mutant of Porphyromonas gingivalis. The Porphyromonas gingivalis strain which is deposited at ATCC under accession number 202109. Also a method of decreasing the growth rate or reproduction rate of Porphyromonas gingivalis in a mammal comprising the step of administering to the mammal at least one dose of Porphyromonas gingivalis according to the present invention. Further, a method of preventing or treating a Porphyromonas gingivalis infection such as periodontitis in a mammal comprising the step of administering to the mammal at least one dose of Porphyromonas gingivalis according to the present invention. Also, a pharmaceutical composition comprising a non-virulent, recA defective mutant of Porphyromonas gingivalis.

    Abstract translation: 牙龈卟啉单胞菌的非毒性recA缺陷突变体。 保藏在ATCC，保藏号为202109的牙龈卟啉单胞菌菌株。还有一种降低哺乳动物牙龈卟啉单胞菌生长速度或繁殖率的方法，包括给予哺乳动物至少一剂根据本发明的牙龈卟啉单胞菌 发明。 此外，预防或治疗牙龈卟啉单胞菌感染如牙周炎的方法包括给予哺乳动物至少一个剂量的根据本发明的牙龈卟啉单胞菌的步骤。 另外，包含牙龈卟啉单胞菌的非毒性recA缺陷突变体的药物组合物。

    SYSTEMS AND METHODOLOGIES FOR PROTON COMPUTED TOMOGRAPHY
    44.
    发明申请
    SYSTEMS AND METHODOLOGIES FOR PROTON COMPUTED TOMOGRAPHY 审中-公开
    用于PROTON计算机图像的系统和方法

    公开(公告)号：WO2011100628A3

    公开(公告)日：2011-10-20

    申请号：PCT/US2011024644

    申请日：2011-02-11

    Applicant: UNIV LOMA LINDA MED ,  UNIV HAIFA ,  UNIV WOLLONGONG ,  CENSOR YAIR ,  PENFOLD SCOTT N ,  SCHULTE REINHARD W

    Inventor： CENSOR YAIR ,  PENFOLD SCOTT N ,  SCHULTE REINHARD W

    IPC: G01N37/00

    CPC classification number: G01T1/2985 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/4258 ,  A61B6/4266 ,  A61B6/5205 ,  A61B6/583 ,  A61N5/10 ,  A61N2005/1087 ,  G01N23/046 ,  G01N2223/419 ,  G01T1/17 ,  G06F19/12 ,  G06F19/24 ,  G06T11/006

    Abstract: Disclosed are systems, devices and methodologies relating to proton computed tomography. In some implementations, detection of protons can yield track information before and after an object for each proton so as to allow determination of a likely path of each proton within the object. Further, measurement of energy loss experienced by each proton allows determination that a given likely path results in a given energy loss. A collection of such data allows characterization of the object. In the context of energy loss, such a characterization can include an image map of relative stopping power of the object. Various reconstruction methodologies for obtaining such an image, including but not limited to superiorization of a merit function such as total variation, are disclosed. In some implementations, various forms of total variation superiorization methodology can yield excellent results while being computationally efficient and with reduced computing time.

    Abstract translation: 公开了与质子计算机断层摄影相关的系统，装置和方法。 在一些实施方案中，质子的检测可以产生每个质子的物体之前和之后的轨道信息，以便允许确定物体内每个质子的可能路径。 此外，每个质子经历的能量损失的测量允许确定给定的可能路径导致给定的能量损失。 这样的数据的集合允许表征对象。 在能量损失的上下文中，这种表征可以包括对象的相对停止力的图像映射。 公开了用于获得这种图像的各种重建方法，包括但不限于诸如总变化的优点功能的优化。 在一些实现中，各种形式的全变异优化方法可以产生优异的结果，同时在计算上有效并且具有减少的计算时间。

    ADVANCED EMERGENCY GEOGRAPHICAL INFORMATION SYSTEM
    46.
    发明申请
    ADVANCED EMERGENCY GEOGRAPHICAL INFORMATION SYSTEM 审中-公开
    先进的紧急地理信息系统

    公开(公告)号：WO2008022051A3

    公开(公告)日：2008-10-30

    申请号：PCT/US2007075751

    申请日：2007-08-10

    Applicant: UNIV LOMA LINDA MED ,  GRANGE JEFF T ,  CORBETT STEPHEN WYNNE

    Inventor： GRANGE JEFF T ,  CORBETT STEPHEN WYNNE

    IPC: G06F17/00 ,  G06F7/00

    CPC classification number: G06F17/30241 ,  G01C21/36 ,  G08B25/009 ,  G08G1/205

    Abstract: A geographical information system ("GIS") for integrating multiple spatial emergency data, multiple non-spatial emergency data or both multiple spatial emergency data and multiple non-spatial emergency data into a real-time GIS for analyzing emergency data. A method for integrating multiple spatial emergency data, multiple non-spatial emergency data or both multiple spatial emergency data and multiple non-spatial emergency data into a real-time GIS for analyzing emergency data.

    Abstract translation: 一种地理信息系统（“GIS”），用于将多个空间紧急数据，多个非空间紧急数据或者多个空间紧急数据和多个非空间紧急数据整合到用于分析紧急数据的实时GIS中。 一种将多个空间紧急事件数据，多个非空间紧急事件数据或者多个空间紧急事件数据和多个非空间紧急事件数据整合到实时GIS中以分析紧急事件数据的方法。

    DEVICE AND METHOD FOR IMMOBILIZING PATIENTS FOR BREAST RADIATION THERAPY
    47.
    发明申请
    DEVICE AND METHOD FOR IMMOBILIZING PATIENTS FOR BREAST RADIATION THERAPY 审中-公开
    用于治疗用于乳腺放射治疗的患者的装置和方法

    公开(公告)号：WO2008064271A3

    公开(公告)日：2008-09-04

    申请号：PCT/US2007085309

    申请日：2007-11-20

    Applicant: UNIV LOMA LINDA MED ,  BUSH DAVID A

    Inventor： BUSH DAVID A

    IPC: G21K5/08

    CPC classification number: A61N5/10 ,  A41C3/00 ,  A61B6/0435 ,  A61N5/1049 ,  A61N2005/1097

    Abstract: According to the improved systems and methods described herein, a patient may be immobilized so that one or both breasts are returned to a known position. Additionally, the improved systems and methods reduce respiratory movement of the breasts. Thus, the immobilization devices and techniques described herein provide accurate and reproducible breast positioning while simultaneously reducing respiratory motion.

    Abstract translation: 根据本文描述的改进的系统和方法，可以固定患者，使得一个或两个乳房返回到已知位置。 此外，改进的系统和方法减少了乳房的呼吸运动。 因此，本文所述的固定装置和技术提供精确和可再现的乳房定位，同时减少呼吸运动。

    LASER HEAD FOR IRRADIATION AND REMOVAL OF MATERIAL FROM A SURFACE OF A STRUCTURE
    49.
    发明申请
    LASER HEAD FOR IRRADIATION AND REMOVAL OF MATERIAL FROM A SURFACE OF A STRUCTURE 审中-公开
    用于从结构表面吸收和去除材料的激光头

    公开(公告)号：WO2004084363A9

    公开(公告)日：2005-12-29

    申请号：PCT/US2004008229

    申请日：2004-03-18

    Applicant: UNIV LOMA LINDA MED ,  DENNEY PAUL E ,  EASTMAN JAY R ,  FALLARA PAUL M

    Inventor： DENNEY PAUL E ,  EASTMAN JAY R ,  FALLARA PAUL M

    IPC: B23K26/08 ,  B23K26/10 ,  B23K26/12 ,  B23K26/16 ,  H01S3/02 ,  B23K26/06 ,  H01S3/00

    CPC classification number: B23K26/0884 ,  B23K26/032 ,  B23K26/0622 ,  B23K26/0643 ,  B23K26/08 ,  B23K26/12 ,  B23K26/123 ,  B23K26/127 ,  B23K26/128 ,  B23K26/1476 ,  B23K26/16 ,  B23K26/206 ,  B23K26/40 ,  B23K37/0217 ,  B23K2203/50

    Abstract: A laser head (1200) is adapted to irradiate an interaction region of an inhabitable structure with laser light to remove material from the structure. The laser head (1200) includes a housing (1230) and a connector (1210) coupled to the housing (1230) and optically coupled to a laser generator. The connector (1210) is adapted to transmit laser light from the laser generator. The laser head (1200) further includes a first optical element (1235) and a second optical element (1235') contained in the housing (1230). The second optical element (1235') is optically coupled to the first optical element (1235). The laser head (1200) further includes a containment plenum (240) coupled to the housing (1200). The containment plenum (240) is optically coupled to the second optical element (1235') to receive the laser light from the second optical element (1235'). The containment plenum (240) is adapted to confine the material and to remove the material from the interaction region resulting from irradiating the structure with the laser light.

    Abstract translation: 激光头（1200）适于用激光照射可居住结构的相互作用区域以从结构中去除材料。 激光头（1200）包括壳体（1230）和连接到壳体（1230）并且光耦合到激光发生器的连接器（1210）。 连接器（1210）适于透射来自激光发生器的激光。 激光头（1200）还包括容纳在壳体（1230）中的第一光学元件（1235）和第二光学元件（1235'）。 第二光学元件（1235'）光耦合到第一光学元件（1235）。 激光头（1200）还包括联接到壳体（1200）的容纳室（240）。 容纳室（240）光耦合到第二光学元件（1235'）以接收来自第二光学元件（1235'）的激光。 容纳室（240）适于限制材料并且从通过用激光照射结构而产生的相互作用区域中移除材料。

    METHOD AND APPARATUS FOR DETECTING EMBEDDED REBAR WITHIN AN INTERACTION REGION OF A STRUCTURE IRRADIATED WITH LASER LIGHT
    50.
    发明申请
    METHOD AND APPARATUS FOR DETECTING EMBEDDED REBAR WITHIN AN INTERACTION REGION OF A STRUCTURE IRRADIATED WITH LASER LIGHT 审中-公开
    用激光照射的结构相互作用区域中检测嵌入雷达的方法和装置

    公开(公告)号：WO2004083794A2

    公开(公告)日：2004-09-30

    申请号：PCT/US2004008219

    申请日：2004-03-18

    Applicant: UNIV LOMA LINDA MED ,  DENNEY PAUL E ,  EASTMAN JAY R ,  HUANG TA-CHIEH

    Inventor： DENNEY PAUL E ,  EASTMAN JAY R ,  HUANG TA-CHIEH

    IPC: B23K26/03 ,  B23K26/12 ,  B23K26/16 ,  G01J

    CPC classification number: B23K26/032 ,  B23K26/03 ,  B23K26/034 ,  B23K26/043 ,  B23K26/12 ,  B23K26/123 ,  B23K26/128 ,  B23K26/142 ,  B23K26/16 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/28

    Abstract: A detection system (600) is used during irradiation of an interaction region of a structure including embedded material with laser light. The detection system (600) includes a collimating lens (610) positioned to receive light emitted from the interaction region. The detection system (600) further includes an optical fiber (620) optically coupled to the collimating lens (610) and a spectrometer (630) optically coupled to the optical fiber (620). The spectrometer (630) is adapted for analysis of the light for indications of the embedded material within the interaction region. The spectrometer (630) includes an input slit (631) adapted to receive light from the optical fiber (620). The input slit (631) has a width selected to provide sufficient light transmittance and sufficient resolution. The spectrometer (630) further includes an optical grating (632) adapted to receive light from the input slit (631) and to separate the light into a spectrum of wavelengths. The spectrometer (630) further includes a collection lens (633) adapted to receive a selected range of wavelengths of the separated light from the optical grating (632). The spectrometer (630) further includes a light sensor (634) adapted to receive the selected range of wavelengths and to generate a signal corresponding to an intensity of the received light.

    Abstract translation: 在包括具有激光的嵌入材料的结构的相互作用区域的照射期间使用检测系统（600）。 检测系统（600）包括准直透镜（610），其定位成接收从相互作用区域发射的光。 检测系统（600）还包括光学耦合到准直透镜（610）的光纤（620）和光学耦合到光纤（620）的光谱仪（630）。 光谱仪（630）适于分析用于指示相互作用区域内的嵌入材料的光。 光谱仪（630）包括适于接收来自光纤（620）的光的输入狭缝（631）。 输入狭缝（631）具有选择的宽度以提供足够的透光率和足够的分辨率。 光谱仪（630）还包括适于接收来自输入狭缝（631）的光并将光分离成波长范围的光栅（632）。 光谱仪（630）还包括适于接收来自光栅（632）的分离光的选定波长范围的收集透镜（633）。 光谱仪（630）还包括适于接收所选择的波长范围的光传感器（634），并产生对应于所接收的光的强度的信号。

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