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    SYSTEMS FOR THE CONTROL OF VALVELESS MICROFLUIDIC DEVICES USING ROTATIONAL AND PISTONING MOTION
    51.
    发明申请
    SYSTEMS FOR THE CONTROL OF VALVELESS MICROFLUIDIC DEVICES USING ROTATIONAL AND PISTONING MOTION 审中-公开

    公开(公告)号：WO2020092254A1

    公开(公告)日：2020-05-07

    申请号：PCT/US2019/058372

    申请日：2019-10-28

    Applicant: TOKITAE LLC

    Inventor： ALONZO, Luis F. ,  CALDERON, Ryan ,  FRIEND, Michael ,  LE NY, Anne-Laure M. ,  MILLER, Andrew K. ,  NICHOLS, Kevin Paul Flood

    IPC: G01N35/02 ,  B01L3/00 ,  B01L9/00 ,  G01N35/04 ,  G01N35/00

    Abstract: Controlling a valveless microfluidic device using rotational and pistoning motion is disclosed. A system embodiment includes, but is not limited to, a stage to support a valveless microfluidic device, the stage having a bottom surface coupled with an extension, having a threaded portion, and defining an interior volume; a first motor including a powered rotating portion operable to engage with the threaded portion to induce a z-axis motion of the stage; a second motor including a powered rotating portion coupled with a slidable coupler, the slidable coupler engaging the interior volume to induce a second motion of the stage about the z-axis; a base defining an aperture to receive the stage; and a lid having a subset of the plurality of apertures corresponding to a subset of a plurality of apertures defined by the valveless microfluidic device upon positioning of the stage by the first motor and the second motor.

    FREEZE-FREE MEDICINAL TRANSPORT CARRIERS
    53.
    发明申请
    FREEZE-FREE MEDICINAL TRANSPORT CARRIERS 审中-公开

    公开(公告)号：WO2018231613A1

    公开(公告)日：2018-12-20

    申请号：PCT/US2018/036396

    申请日：2018-06-07

    Applicant: TOKITAE LLC

    Inventor： CHOU, Fong-Li ,  PAL, Brian L. ,  PETERS, Matthew W. ,  PETERSON, Nels R. ,  YAGER, David J.

    IPC: B65D81/18 ,  B65D81/38 ,  B65D1/24 ,  F28D20/02 ,  A61J1/05

    Abstract: In some embodiments, a medicinal carrier device includes: one or more sections of thermal insulation positioned to form an internal space with an adjacent first side region and an adjacent second side region; a first panel including a first phase change material positioned within the first side region of the internal space, the first side region of a size and shape to firmly contain an integral number of portable cold packs in thermal contact with the first panel; and a second panel including a second phase change material positioned within the second side region of the internal space, the second side region of a size and shape to firmly contain an integral number of portable cold packs in thermal contact with the second panel.

    THERMOSIPHONS FOR USE WITH TEMPERATURE-REGULATED STORAGE DEVICES
    55.
    发明申请
    THERMOSIPHONS FOR USE WITH TEMPERATURE-REGULATED STORAGE DEVICES 审中-公开
    用于温度调节存储设备的热电偶

    公开(公告)号：WO2018022567A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/043638

    申请日：2017-07-25

    Applicant: TOKITAE LLC

    Inventor： CHOU, Fong-Li ,  LARUSSON, Fridrik ,  PAL, Brian L. ,  PETERSON, Nels R. ,  WOOD, Lowell L., Jr.

    IPC: F28D15/02 ,  F28D15/06 ,  F28D20/02 ,  F28D20/00

    Abstract: In some embodiments, a thermosiphon configured for use within a temperature-regulated storage device includes: a condenser region, including a plurality of evenly spaced condenser channels with horizontally symmetrical bifurcated branches connected to an adiabatic channel, each of the plurality of condenser channels connected at a top position to an upper channel; an evaporator region, including a plurality of evaporator channels, wherein each of the plurality of evaporator channels has a flow channel formed in a serpentine channel pattern and each subunit of the serpentine channel pattern is attached to a vapor return channel at a top of the subunit, and wherein the evaporator region has at least one lowest position connected directly to a vapor return channel; and an adiabatic region including at least one adiabatic channel connecting the evaporator channels and the condenser channels.

    Abstract translation: 在一些实施例中，配置用于在温度调节储存装置内使用的热虹吸管包括：冷凝器区域，其包括多个均匀间隔的冷凝器通道，其具有连接到绝热通道的水平对称的分叉分支，每个 所述多个冷凝器通道中在顶部位置处连接至上部通道; 蒸发器区域，所述蒸发器区域包括多个蒸发器通道，其中所述多个蒸发器通道中的每一个均具有形成为蛇形通道图案的流动通道，并且所述蛇形通道图案的每个子单元附接至所述子单元的顶部处的蒸气返回通道 并且其中所述蒸发器区域具有至少一个直接连接至蒸汽返回通道的最低位置; 以及包括至少一个连接蒸发器通道和冷凝器通道的绝热通道的绝热区。

    THERMAL EXPANSION ACTUATORS, MICROSCOPES INCLUDING THE SAME, AND RELATED METHODS
    56.
    发明申请
    THERMAL EXPANSION ACTUATORS, MICROSCOPES INCLUDING THE SAME, AND RELATED METHODS 审中-公开
    热膨胀促动器，包括其的显微镜，以及相关方法

    公开(公告)号：WO2017155560A1

    公开(公告)日：2017-09-14

    申请号：PCT/US2016/036160

    申请日：2016-06-07

    Applicant: TOKITAE LLC

    Inventor： CALDERON, Ryan ,  GASPERINO, David ,  MCGUIRE, Shawn Keith ,  ROECKER, James Andrew

    IPC: G01N25/34 ,  G01N25/32

    CPC classification number: G02B21/26

    Abstract: Embodiments disclosed herein include thermal expansion actuators, systems using the same (e.g., microscopes), and methods of using the same. The thermal expansion actuators disclosed herein can include at least one beam coupled to and extending between a plurality of support portions. The thermal expansion actuators also include at least one heating element configured to heat at least a portion of the thermal expansion actuators, such as the at least one beam. The support portions are coupled to an structure (e.g., a component of a microscope) in a manner that at least partially restrains thermal expansion or contraction of the thermal expansion actuators in at least one direction when the thermal expansion actuators are heated or cooled, respectively. Restraining the thermal expansion actuators can controllably and selectively produce relative movement in the at least one beam (e.g., deflected). For example, the thermal expansion actuators can be heated or cooled to controllably and selectively deflect the beam in 1 µm displacements or less.

    Abstract translation: 这里公开的实施例包括热膨胀致动器，使用其的系统（例如，显微镜）以及使用该系统的方法。 本文公开的热膨胀致动器可以包括耦合到多个支撑部分并且在多个支撑部分之间延伸的至少一个梁。 热膨胀致动器还包括至少一个加热元件，其构造成加热至少一部分热膨胀致动器，例如至少一个梁。 支撑部分以这样的方式联接至结构（例如，显微镜的部件）：当热膨胀致动器分别被加热或冷却时，至少部分地限制热膨胀致动器在至少一个方向上的热膨胀或收缩 。 限制热膨胀致动器可以可控地且有选择地在至少一个梁（例如，偏转）中产生相对运动。 例如，可以对热膨胀致动器进行加热或冷却，以可控制的方式选择性地偏转1微米或更小位移量的梁。

    REFRIGERATION DEVICES INCLUDING TEMPERATURE-CONTROLLED CONTAINER SYSTEMS
    59.
    发明申请
    REFRIGERATION DEVICES INCLUDING TEMPERATURE-CONTROLLED CONTAINER SYSTEMS 审中-公开
    包括温度控制容器系统的制冷装置

    公开(公告)号：WO2016179215A1

    公开(公告)日：2016-11-10

    申请号：PCT/US2016/030658

    申请日：2016-05-04

    Applicant: TOKITAE LLC

    Inventor： CHOU, Fong-Li ,  ECKHOFF, Philip A. ,  FOWLER, Lawrence Morgan ,  GATES, William ,  HU, Jenny Ezu ,  ISHIKAWA, Muriel Y. ,  LARUSSON, Fridrik ,  LIU, Shieng ,  MYHRVOLD, Nathan P. ,  PAL, Brian L. ,  PETERSON, Nels R. ,  PIECH, David Keith ,  VECCHIONE, Maurizio ,  WOOD, Lowell L., Jr. ,  WOOD, Victoria Y.H. ,  YAGER, David J.

    IPC: F25D23/06 ,  F25B39/02 ,  F25B39/04 ,  F25D23/02 ,  F25D29/00

    CPC classification number: F25D16/00 ,  F25B23/006 ,  F25D11/006

    Abstract: In some embodiments, a refrigeration device includes: walls substantially forming a liquid-impermeable container configured to hold phase change material internal to a refrigeration device; at least one active refrigeration unit including a set of evaporator coils positioned within an interior of the liquid-impermeable container; walls substantially forming a storage region; and a heat transfer system including a first group of vapor-impermeable structures with a hollow interior connected to form a condenser in thermal contact with the walls substantially forming a liquid-impermeable container, a second group of vapor-impermeable structures with a hollow interior connected to form an evaporator in thermal contact with the walls substantially forming a storage region, and a connector with a hollow interior affixed to both the condenser and the evaporator, the connector forming a liquid and vapor flow path between the hollow interior of the condenser and the hollow interior of the evaporator.

    Abstract translation: 在一些实施例中，制冷装置包括：基本上形成液体不可渗透容器的壁，其构造成将相变材料保持在制冷装置内部; 至少一个主动制冷单元，其包括位于所述液体不可渗透容器内部的一组蒸发器盘管; 基本上形成存储区域的壁; 以及传热系统，其包括具有中空内部的第一组不透气结构，以形成基本上形成液体不可渗透容器的与所述壁热接触的冷凝器，具有中空内部连接的第二组蒸气不可渗透结构 以形成与基本上形成存储区域的壁热接触的蒸发器，以及具有固定到冷凝器和蒸发器两者的中空内部的连接器，所述连接器在冷凝器的中空内部和所述冷凝器之间形成液体和蒸气流动路径 中空的蒸发器内部。

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