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1.发明申请
公开(公告)号：WO2015054695A2
公开(公告)日：2015-04-16
申请号：PCT/US2014/060462
申请日：2014-10-14
Applicant: IMMUNETICS, INC.
Inventor： PINKOWITZ, Richard, A. , OCKHAM, Michael, J. , WILLIAMS, Gregory, V. , KRUEGER, Neil, X. , HAN, Andrew , MUNGO, Lynda, S. , DOWLING, James, L. , MINAHAN, Jason, S. , KESSLER, Jack , CHEVALIER, Gary , LACROIX, Roger, T.
CPC classification number: G01N33/5091 , G01N1/38 , G01N21/272 , G01N21/274 , G01N21/78 , G01N33/48792 , G01N35/00871 , G01N2001/4088 , G01N2035/0091 , G01N2333/90245
Abstract: Assay devices, assay detection systems, and methods comprising same for analytical tests, medical assays, diagnostic tests, medical diagnosis, risk assessment, or quality control purposes are provided. These devices, systems, and methods are designed to be employed at the point of care, such as in emergency rooms, operating rooms, hospital laboratories and other clinical laboratories, doctor's offices, in the field, or in any situation in which a rapid and accurate result is desired. The systems and methods process samples, such as clinical, biological, or blood sample, and read data from colorimetric based biochemical assays to provide an indication of the presence or absence of a bacterial, fungal, or viral contaminants therein. The assay devices include an optical reader apparatus and barcode scanner for reading and matching the test results to identification information provided by the barcodes to facilitate ease of tracking compliant and noncompliant samples.
Abstract translation: 提供了用于分析测试，医学分析，诊断测试，医学诊断，风险评估或质量控制目的的分析装置，分析检测系统和包括它们的方法。 这些设备，系统和方法被设计为在护理点使用，例如在急诊室，手术室，医院实验室和其他临床实验室，医生办公室，野外或任何情况下 准确的结果是期望的。 该系统和方法处理样品，如临床，生物或血液样品，并从基于比色的生物化学测定中读取数据以提供其中存在或不存在细菌，真菌或病毒污染物的指示。 该测定装置包括光学读取器装置和条形码扫描器，用于读取测试结果并将其与条形码提供的识别信息相匹配，以便于追踪顺从和不顺从的样品。
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公开(公告)号：WO2015042288A1
公开(公告)日：2015-03-26
申请号：PCT/US2014/056355
申请日：2014-09-18
Applicant: L2 DIAGNOSTICS, LLC
Inventor： USMANI-BROWN, Sahar
CPC classification number: C12Q1/6883 , C12Q2600/154 , C12Q2600/16
Abstract: Described herein are compositions and methods for diagnosing or monitoring type 1 diabetes.
Abstract translation: 本文描述了用于诊断或监测1型糖尿病的组合物和方法。
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公开(公告)号：WO2011140464A9
公开(公告)日：2011-11-10
申请号：PCT/US2011/035559
申请日：2011-05-06
Inventor： JAMIESON, Jr., Gordon, A.
Abstract: Provided is a highly sensitive high throughput mass spectrometry-based quantitative assay for 4E/4E regulon pathway proteins has been developed which provides for single sample multiplexed analysis, as well as the analysis of protein phosphorylation states. It may be adapted for use as the first single sample analytical method of the 4E/4E regulon biological pathway.
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4.发明申请
公开(公告)号：WO2011088365A1
公开(公告)日：2011-07-21
申请号：PCT/US2011/021362
申请日：2011-01-14
Applicant: ORGANOGENESIS, INC. , RONFARD, Vincent , BAKSH, Dolores , WANG, Xianyan , WONG, Matthew, Quin-men , CAO, Lan , SAVA, Parid , BOLLENBACH, Thomas , YESILALAN, Esin
Inventor： RONFARD, Vincent , BAKSH, Dolores , WANG, Xianyan , WONG, Matthew, Quin-men , CAO, Lan , SAVA, Parid , BOLLENBACH, Thomas , YESILALAN, Esin
IPC: C12N5/0775 , A61L27/36
CPC classification number: C12N5/0663 , A61K2035/124 , A61L27/3633 , A61L27/3804 , A61L27/3834 , A61L27/3886 , A61L27/3891 , C12N5/0667 , C12N5/0668 , C12N2500/25 , C12N2500/38 , C12N2500/90 , C12N2501/02 , C12N2501/11 , C12N2501/115 , C12N2501/148 , C12N2501/39 , C12N2533/90
Abstract: Bioengineered constructs are formed from cultured cells induced to synthesize and secrete endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. The bioengineered constructs of the invention can be produced with multiple cell types that can all contribute to producing the extracellular matrix. Additionally or alternatively, one of the multiple cell types can be delivered to a site in the body via the endogenously produced extracellular matrix components to achieve various therapeutic benefits.
Abstract translation: 生物工程化构建体由诱导合成和分泌内源性产生的细胞外基质组分的培养细胞形成，而不需要外源基质组分或网络支持物或支架构件。 本发明的生物工程化构建体可以用多种可以有助于产生细胞外基质的细胞类型产生。 另外或替代地，多种细胞类型中的一种可以通过内源产生的细胞外基质组分递送到体内的位点，以实现各种治疗益处。
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公开(公告)号：WO2010080985A8
公开(公告)日：2010-07-15
申请号：PCT/US2010/020480
申请日：2010-01-08
Inventor： SPIEGELMAN, Bruce, M. , KAJIMUIRA, Shingo
Abstract: The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of both Prdmlβ and C/EBPβ activity and/or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subject through stimulation of both Prdmlβ and C/EBPβ expression and/or activity. Further provided are methods for identifying compounds that are capable of modulating both Prdmlβ and C/EBPβ expression and/or activity.
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Patent Agency Ranking
公开(公告)号：WO2010025176A2
公开(公告)日：2010-03-04
申请号：PCT/US2009/055027
申请日：2009-08-26
Applicant: ORGANOGENESIS, INC. , BOWLIN, Gary, L. , SMITH, Matthew, J. , WHITE, Kimber, L., Jr.
Inventor： BOWLIN, Gary, L. , SMITH, Matthew, J. , WHITE, Kimber, L., Jr.
CPC classification number: A61K38/195 , A61L27/54 , A61L2300/252 , A61L2300/426 , A61L2300/602
Abstract: The present invention is directed to methods and compositions related to electroprocessed drug delivery devices. An electroprocessed drug delivery device of the present invention can, for example, be made to comprise an electrospun scaffold (e.g. , comprising polydioxanone) incorporated with Monocyte Chemotactic Protein- 1 (MCP-I). The electroprocess drug delivery device can be used to influence macrophage infiltration and adherence, and to allow extended chemokine release.
Abstract translation: 本发明涉及与电加工药物递送装置相关的方法和组合物。 本发明的电加工药物递送装置可以例如制成包含掺入单核细胞趋化蛋白-1（MCP-1）的静电纺丝支架（例如，包含聚二恶烷酮）。 电加工药物递送装置可用于影响巨噬细胞浸润和粘附，并允许扩展趋化因子释放。
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公开(公告)号：WO2008021862A3
公开(公告)日：2008-02-21
申请号：PCT/US2007/075441
申请日：2007-08-08
Applicant: BINAX, INC. , DAVIS, Alan, H.
Inventor： DAVIS, Alan, H.
IPC: C12N1/12
Abstract: Provided are compositions, methods and devices for detecting M. pneumoniae in a sample.
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公开(公告)号：WO2007084857A3
公开(公告)日：2007-07-26
申请号：PCT/US2007/060504
申请日：2007-01-12
Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE , SINCLAIR, David, A. , BAUR, Joseph, A. , ARMOUR, Sean, M.
Inventor： SINCLAIR, David, A. , BAUR, Joseph, A. , ARMOUR, Sean, M.
Abstract: The present invention provides methods for treating and preventing cell proliferative disorders and conditions comprising administering to a subject resveratrol or an analog thereof.
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公开(公告)号：WO2006110706A3
公开(公告)日：2006-10-19
申请号：PCT/US2006/013407
申请日：2006-04-11
Applicant: ZE-GEN, INC. , DAVIS, William, H. , POLOVTSEV, Igor
Inventor： DAVIS, William, H. , POLOVTSEV, Igor
Abstract: Processes and apparatus for treating organic and inorganic materials in a metal bath contained in a high temperature reactor to produce synthesis gas are provided. The feed materials are prepared and analyzed for heat value prior to injection and the composition of materials in and exiting the reactor are monitored. Based upon the results of the analysis and monitoring, oxygen, steam, and/or other feed materials are also injected into the reactor, to control processing and synthesis gas quality.
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公开(公告)号：WO2005021756A1
公开(公告)日：2005-03-10
申请号：PCT/US2004/028143
申请日：2004-08-30
Applicant: CHILDREN'S MEDICAL CENTER CORPORATION , FOLKMAN, Judah , JAVAHERIAN, Kashi
Inventor： FOLKMAN, Judah , JAVAHERIAN, Kashi
IPC: C12N15/11
Abstract: Provided herein are anti-angiogenic comprising the N-terminal end of endostatin, nucleic acids encoding the same, pharmaceutical preparations comprising an effective amount of the peptide and nucleic acids and use of the pharmaceuticals in treating or preventing diseases or conditions associated with undesirable angiogenesis.
Abstract translation: 本文提供了包含内皮抑素的N末端，编码它的核酸，包含有效量的肽和核酸的药物制剂以及药物在治疗或预防与不期望的血管发生相关的疾病或病症中的用途的抗血管生成。
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