公开(公告)号：WO2013123623A1

公开(公告)日：2013-08-29

申请号：PCT/CN2012/000239

申请日：2012-02-24

Applicant: 量子高科(北京)研究院有限公司 ,  王丛威 ,  王洪飞 ,  刘荣 ,  周立运

Inventor： 王丛威 ,  王洪飞 ,  刘荣 ,  周立运

IPC: A61K9/20 ,  A61K47/36 ,  A61K47/42 ,  A61K8/73 ,  A61K8/02 ,  A61K8/81 ,  A61J3/00 ,  A23L1/05

CPC classification number: A61K8/73 ,  A61J3/10 ,  A61K8/0216 ,  A61K9/0056 ,  A61K9/205 ,  A61K9/2095 ,  A61K2800/10 ,  A61K2800/222 ,  A61K2800/92 ,  A61Q19/00

Abstract: 一种口腔崩解片及其制备方法，采用冷冻干燥法制备而得，其组分包括有效剂量的药物活性成分、骨架支持剂、粘结剂和助悬剂，其中粘结剂由普鲁兰和辅助粘结剂组成。本发明利用普鲁兰和辅助粘结剂在特定用量范围下的复配使用，解决了冻干型口腔崩解片在装载大剂量药物时崩解缓慢、溶出不完全的问题。

公开(公告)号：WO2007071179A1

公开(公告)日：2007-06-28

申请号：PCT/CN2006/003487

申请日：2006-12-19

Applicant: 量子高科 ,  李和伟 ,  王丛威 ,  杜波 ,  贾成功 ,  焦仕荣 ,  吉春

Inventor： 李和伟 ,  王丛威 ,  杜波 ,  贾成功 ,  焦仕荣 ,  吉春

IPC: A61J3/00 ,  B32B15/08 ,  B65D75/36

CPC classification number: A61J3/06 ,  A61J1/035 ,  A61K9/0056 ,  B32B3/28 ,  B32B15/08 ,  B32B15/20

Abstract: A method for manufacturing an oral disintegrating preparation, comprising: (a) molding a complex aluminum substrate material with blister molding equipment, forming a plurality of depressions in the said complex aluminum substrate material, the said complex aluminum substrate material comprises an intermediate aluminum layer, a first and second outer layers, the material of the first outer layer differs from the second outer layer, the flexural rigidity of the first outer layer differs the second outer layer by 0-30%; (b) filling a liquid pharmaceuticals into the depressions formed in the step (a); (c) freezing the pharmaceuticals; (d) freeze-drying the pharmaceuticals; (e) attaching a lidding material to the said package material to seal the pharmaceuticals.

公开(公告)号：WO2006081706A1

公开(公告)日：2006-08-10

申请号：PCT/CN2005/000166

申请日：2005-02-05

Applicant: 量子高科 ,  王丛威 ,  李和伟 ,  王彦峰 ,  王洪飞

Inventor： 王丛威 ,  李和伟 ,  王彦峰 ,  王洪飞

IPC: B65D5/50 ,  B65D75/34 ,  A61J1/03

CPC classification number: A61J1/03 ,  A61J1/035 ,  B65D83/0445

Abstract: The present invention relates to a Packaging Box for Medicaments, which comprises: a bottom panel (1); a first-top panel (4); a second-top panel (5); a first-side panel (3a), being between said bottom panel (1) and first-top panel (4) and connected to them; a second-side panel (3b), being between said bottom panel (1) and second-top panel (5) and connected to them; a third-top panel (6), being connected to the second-top panel (5) and being opposite to said second-side panel (3b); some blisters (8) for the storage of medicaments, being provided on the third-top panel (6) and protruding therefrom; and supporting means (2), being provided on the internal surface of said bottom panel (1) so as to support said third-top panel (6).