公开(公告)号：WO2016069243A1

公开(公告)日：2016-05-06

申请号：PCT/US2015/054895

申请日：2015-10-09

Applicant: 21, INC.

Inventor： KHETERPAL, Veerbhan ,  FIRU, Daniel ,  DREGO, Nigel

IPC: G06Q20/36 ,  G06Q40/04 ,  G06Q20/38 ,  H04L9/06

CPC classification number: G06F17/30539 ,  G06F17/30864 ,  G06Q20/06 ,  G06Q20/3678 ,  G06Q20/3827 ,  G06Q40/04 ,  H04L9/0643 ,  H04L9/3236 ,  H04L2209/30 ,  H04L2209/38

Abstract: An integrated circuit may be provided with cryptocurrency mining capabilities. The integrated circuit may include control circuitry and a number of processing cores that complete a Secure Hash Algorithm 256 (SHA-256) function in parallel. Logic circuitry may be shared between multiple processing cores. Each processing core may perform sequential rounds of cryptographic hashing operations based on a hash input and message word inputs. The control circuitry may control the processing cores to complete the SHA-256 function over different search spaces. The shared logic circuitry may perform a subset of the sequential rounds for multiple processing cores. If desired, the shared logic circuitry may generate message word inputs for some of the sequential rounds across multiple processing cores. By sharing logic circuitry across cores, chip area consumption and power efficiency may be improved relative to scenarios where the cores are formed using only dedicated logic.

Abstract translation: 集成电路可以提供密码学挖掘功能。 集成电路可以包括并行地完成安全散列算法256（SHA-256）功能的控制电路和多个处理核心。 逻辑电路可以在多个处理核之间共享。 每个处理核心可以基于散列输入和消息字输入来执行连续循环的加密散列操作。 控制电路可以控制处理核心以在不同的搜索空间上完成SHA-256功能。 共享逻辑电路可以执行多个处理核的顺序循环的子集。 如果需要，共享逻辑电路可以跨多个处理核心的一些顺序循环产生消息字输入。 通过跨核心共享逻辑电路，相对于仅使用专用逻辑形成核心的情况，可以提高芯片面积消耗和功率效率。

公开(公告)号：WO2016060931A1

公开(公告)日：2016-04-21

申请号：PCT/US2015/054708

申请日：2015-10-08

Applicant: 21, INC.

Inventor： KHETERPAL, Veerbhan ,  FIRU, Daniel ,  DREGO, Nigel

IPC: G06F17/50

CPC classification number: G06F17/5045 ,  G06F17/505 ,  G06F17/5072 ,  G06F2217/08 ,  G06F2217/62

Abstract: Circuit design equipment may design logic for a circuit. The design equipment may discover optimized design constraints and an optimized clock signal frequency for the circuit. The design equipment may output the discovered optimized clock signal frequency and design constraints to circuit fabrication equipment for fabricating the corresponding circuit. The design equipment may discover the optimized clock signal frequency and design constraints by populating a cost function with different clock signal frequencies and different design constraint values. The cost function may be, for example, a multi-dimensional surface. The design equipment may identify a global minimum of the cost function and may identify the clock signal frequency and design constraint values that correspond to the global minimum as the optimized clock frequency and optimized design constraints to provide to circuit fabrication equipment. The fabrication equipment may fabricate the circuit to implement the optimized design constraint values and clock frequency.

Abstract translation: 电路设计设备可以为电路设计逻辑。 设计设备可能会发现电路的优化设计约束和优化的时钟信号频率。 设计设备可以将发现的优化时钟信号频率和设计约束输出到用于制造相应电路的电路制造设备。 设计设备可以通过填充具有不同时钟信号频率和不同设计约束值的成本函数来发现优化的时钟信号频率和设计约束。 成本函数可以是例如多维表面。 设计设备可以识别成本函数的全局最小值，并且可以将对应于全局最小值的时钟信号频率和设计约束值识别为优化的时钟频率和为电路制造设备提供的优化设计约束。 制造设备可以制造电路以实现优化的设计约束值和时钟频率。

公开(公告)号：WO2011002939A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/040679

申请日：2010-06-30

Applicant: NUTRITION 21, INC. ,  KOMOROWSKI, James, R.

Inventor： KOMOROWSKI, James, R.

IPC: A01N55/02 ,  A61K31/28

CPC classification number: A61K33/24 ,  A61K31/555

Abstract: The embodiments disclosed herein relate to compositions for enhancing brain glucose transporters, such as GLUTl and GLUT3, and methods of treating and/or preventing diseases or disorders associated with the regulation GLUTl and GLUT3. Also provided are compositions that include chromium and an agent that targets the brain or the central nervous system. Further provided are improved methods of delivering therapeutic agents that target the brain and/or central nervous system.

Abstract translation: 本文公开的实施方案涉及用于增强脑葡萄糖转运蛋白的组合物，例如GLUT1和GLUT3，以及治疗和/或预防与调节GLUT1和GLUT3相关的疾病或病症的方法。 还提供了包含铬和靶向脑或中枢神经系统的药剂的组合物。 进一步提供了递送针对脑和/或中枢神经系统的治疗剂的改进方法。

公开(公告)号：WO2009009393A4

公开(公告)日：2009-04-23

申请号：PCT/US2008069079

申请日：2008-07-02

Applicant: NUTRITION 21 INC ,  KOMOROWSKI JAMES ,  JUTURU VIJAYA

Inventor： KOMOROWSKI JAMES ,  JUTURU VIJAYA

IPC: A61K31/555 ,  A61K33/24

CPC classification number: A61K33/24

Abstract: A method of treating impaired memory and/or cognitive function by administering one or more chromium complexes, for example chromium picolinate, to an individual in need of improved memory and/or cognitive function. This method is used to improve memory and/or cognitive function associated with various disorders, including Alzheimer's disease, dementia, and mild cognitive impairment (MCI). Chromium complexes for treating memory or cognitive impairment are also disclosed.

Abstract translation: 通过向需要改善的记忆和/或认知功能的个体施用一种或多种铬配合物，例如吡啶甲酸铬来治疗受损记忆和/或认知功能的方法。 该方法用于改善与各种疾病相关的记忆和/或认知功能，包括阿尔茨海默病，痴呆和轻度认知障碍（MCI）。 还公开了用于治疗记忆或认知障碍的铬络合物。

公开(公告)号：WO2008103740A1

公开(公告)日：2008-08-28

申请号：PCT/US2008/054436

申请日：2008-02-20

Applicant: INTECH 21, INC. ,  KATS, Marat ,  ZELMANOVICH, Helena ,  TCHIBIREV, Igor ,  IZVARIN, Yuriy

Inventor： KATS, Marat ,  ZELMANOVICH, Helena ,  TCHIBIREV, Igor ,  IZVARIN, Yuriy

IPC: H04Q7/24

CPC classification number: H04W8/30

Abstract: The present invention comprises a plurality of timely organized ad hoc data communications networks and a method for data communication. A network from the plurality of networks includes media-independent communications links and plurality of network nodes, where a network node in the plurality could be coupled to at least one other network node via a media independent communication link, and a plurality of access points, where each access point in the plurality is coupled to at least one other access point via another media-independent communications link. The network communicates during a data collection cycle that includes a broadcast interval, a time-slotted communications interval and a random access time-slotted communications interval. The plurality of network nodes are arranged in a self-assigned hierarchy where one or more nodes in the plurality of network nodes can be assigned more than one time slot to transmit the network information messages.

Abstract translation: 本发明包括多个及时组织的自组织数据通信网络和数据通信方法。 来自多个网络的网络包括媒体无关的通信链路和多个网络节点，其中多个网络节点可经由媒体无关的通信链路和多个接入点与至少一个其他网络节点耦合， 其中多个中的每个接入点经由另一媒体独立通信链路耦合到至少一个其他接入点。 网络在包括广播间隔，时隙通信间隔和随机访问时隙通信间隔的数据收集周期期间进行通信。 多个网络节点被布置在自分配层级中，其中多个网络节点中的一个或多个节点可被分配多于一个时隙以发送网络信息消息。

公开(公告)号：WO2003090671A2

公开(公告)日：2003-11-06

申请号：PCT/US2003/010717

申请日：2003-04-03

Applicant: NUTRITION 21, INC. ,  JUTURU, Vijaya ,  KOMOROWSKI, James, R. ,  MONTGOMERY, Gail

Inventor： JUTURU, Vijaya ,  KOMOROWSKI, James, R. ,  MONTGOMERY, Gail

IPC: A61K

CPC classification number: A61K31/155 ,  A61K31/13 ,  A61K33/24 ,  A61K45/06 ,  A61K2300/00

Abstract: A method for inhibiting drug-induced insulin resistance is provided which includes administering a dietary chromium complex to an individual receiving a contemporaneous dose of a drug that induces insulin resistance, wherein the amount of chromium complex administered is an amount effective to inhibit the development of insulin resistance. Advantageously, the amount of chromium complex administered per day is between about 300 and 1,000 micrograms per day. Compositions including a drug which induces insulin resistance in combination with a chromium complex are similarly described.

Abstract translation: 提供了一种抑制药物诱导的胰岛素抵抗的方法，其包括向接受同时代剂量的诱导胰岛素抵抗的药物的个体施用膳食铬复合物，其中施用的铬复合物的量是有效抑制胰岛素发展的量 抵抗性。 有利地，每天施用的铬复合物的量为约300至1,000微克/天。 类似地描述了包括与铬复合物组合诱导胰岛素抵抗的药物的组合物。

公开(公告)号：WO1994016534A2

公开(公告)日：1994-07-21

申请号：PCT/US1993012520

申请日：1993-12-21

Applicant: COM 21, INC.

Inventor： COM 21, INC. ,  BARAN, Paul

IPC: H04Q11/04

CPC classification number: H04Q11/0478 ,  H04L2012/5605 ,  H04L2012/5606 ,  H04L2012/561 ,  H04L2012/5631 ,  H04N7/173 ,  H04N7/17309 ,  Y10S370/906

Abstract: 53 byte length ATM compliant cells are transmitted over a digital optical fiber path to interconnect with a coaxial feeder cable TV system to support two-way digital services at a plurality of sites connected to the TV cable system. At the point of interconnection between the fiber optic path and the cable TV feeder subsystem, digital signals are converted to a UHF rf carrier frequency above the cutoff pass-band of the analog signal feeder amplifier carrying TV broadcast signals. This rf carrier conveys a high data rate digitally modulated signal limited to sections of feeder cable between the cable TV broadcast channel amplifiers. In-house access to this UHF carrier signal is via the normal TV cable tap and drop cable to an SIU, located near the subscriber's TV set. The feeder cable and the passive taps used in cable TV practice have a higher cutoff frequency than the feeder amplifiers themselves. This allows passage of a UHF signal over the feeder cable. Low pass filters at the feeder amplifiers prevent this UHF signal from being shorted out by the in-cable amplifiers. Each SIU so connected sends and receives the UHF carrier signal, which conveys the ATM type cells. Each cell's payload contains the local address of the source and destination of that cell. Each SIU decodes each cell's address and accepts only those cells that are for itself. The SIUs speak to and receive signals from an FTU located at the TV cable headend or at a fiber connection node. The common channel conveying the ATM cells alternatively sends and receives cells in a ping-pong fashion.

Abstract translation: 53字节长度的ATM兼容小区通过数字光纤路径传输，以与同轴馈线有线电视系统互连，以在连接到TV电缆系统的多个站点处支持双向数字业务。 在光纤路径和有线电视馈线子系统之间的互连点，数字信号被转换成高于载有TV广播信号的模拟信号馈线放大器的截止频带上的UHF rf载波频率。 该rf载波传输限制在有线电视广播信道放大器之间的馈线电缆部分的高数据速率数字调制信号。 通过正常的电视电缆将内部访问的UHF载波信号通过分接电缆连接到位于用户电视机附近的SIU。 有线电视实践中使用的馈线电缆和被动水龙头具有比馈线放大器本身更高的截止频率。 这允许UHF信号通过馈线电缆。 馈线放大器的低通滤波器可防止该UHF信号被有线放大器短路。 如此连接的每个SIU发送和接收传送ATM型信元的UHF载波信号。 每个单元的有效载荷包含该单元的源和目的地的本地地址。 每个SIU都会对每个单元格的地址进行解码，并且只接受那些单独的单元格。 SIU对位于电视电缆前端或光纤连接节点处的FTU进行信号接收和接收。 传送ATM信元的公共信道以乒乓方式交替地发送和接收信元。

公开(公告)号：WO2009009393A3

公开(公告)日：2009-03-05

申请号：PCT/US2008069079

申请日：2008-07-02

Applicant: NUTRITION 21 INC ,  KOMOROWSKI JAMES ,  JUTURU VIJAYA

Inventor： KOMOROWSKI JAMES ,  JUTURU VIJAYA

IPC: A61K31/555 ,  A61K33/24

CPC classification number: A61K33/24

Abstract: A method of treating impaired memory and/or cognitive function by administering one or more chromium complexes, for example chromium picolinate, to an individual in need of improved memory and/or cognitive function. This method is used to improve memory and/or cognitive function associated with various disorders, including Alzheimer's disease, dementia, and mild cognitive impairment (MCI). Chromium complexes for treating memory or cognitive impairment are also disclosed.

Abstract translation: 通过向需要改善记忆和/或认知功能的个体施用一种或多种铬络合物（例如吡啶甲酸铬）来治疗受损记忆和/或认知功能的方法。 该方法用于改善与各种疾病相关的记忆和/或认知功能，包括阿尔茨海默病，痴呆和轻度认知障碍（MCI）。 还公开了用于治疗记忆或认知障碍的铬复合物。

公开(公告)号：WO2006093796A2

公开(公告)日：2006-09-08

申请号：PCT/US2006/006440

申请日：2006-02-24

Applicant: YAHOO!21 INC. ,  ROGERS, Ian ,  NEW, Matthew, D. ,  BROWN, David, E.

Inventor： ROGERS, Ian ,  NEW, Matthew, D. ,  BROWN, David, E.

IPC: G06Q10/10 ,  G06Q20/12 ,  G06Q30/02 ,  G06Q30/06

CPC classification number: G06F17/30578 ,  G06F17/30053 ,  G06F17/30056 ,  G06F17/30684 ,  G06F17/30766 ,  G06F17/30772 ,  G06F17/30867 ,  G06F21/10 ,  G06F21/6236 ,  G06F2213/0038 ,  G06F2216/01 ,  G06F2221/2113 ,  G06F2221/2137 ,  G06Q10/10 ,  G06Q20/1235 ,  G06Q30/02 ,  G06Q30/06 ,  G11B20/00086 ,  G11B27/105 ,  G11B27/34 ,  H04L12/1822 ,  H04L29/06027 ,  H04L51/04 ,  H04L63/0263 ,  H04L63/101 ,  H04L63/105 ,  H04L65/4084 ,  H04L67/06 ,  H04L67/22 ,  H04L67/306 ,  H04L67/325 ,  H04L67/327 ,  H04L67/34 ,  H04L2463/101 ,  H04N7/17318 ,  H04N21/2541 ,  H04N21/4126 ,  H04N21/41407 ,  H04N21/4331 ,  H04N21/4622 ,  H04N21/4627 ,  H04N21/47214 ,  H04N21/4788 ,  H04N21/4825 ,  H04N21/658 ,  H04N21/8113 ,  H04N21/8355 ,  Y10S707/913

Abstract: A system and method for storing a playlist of media files that is accessible from various locations in a network. In one aspect, the playlist is accessible from multiple users of the network. A method is also described for arranging the media files of a playlist. In one aspect, the method for arranging the media files is based in part on implicit and/or explicit user behavior.

Abstract translation: 一种用于存储可从网络中的各个位置访问的媒体文件的播放列表的系统和方法。 在一个方面，播放列表可以从网络的多个用户访问。 还描述了一种用于布置播放列表的媒体文件的方法。 一方面，用于布置媒体文件的方法部分地基于隐式和/或显式用户行为。

公开(公告)号：WO2004017913A3

公开(公告)日：2004-03-04

申请号：PCT/US2003/026370

申请日：2003-08-22

Applicant: NUTRITION 21, INC.

Inventor： JUTURU, Vijaya ,  KOMOROWSKI, James, R.

IPC: A61K31/70

Abstract: A method for preventing and treating a variety of disease states and disorders is provided, comprising the administration of an arginine silicate inositol complex to an individual in the presence of medical therapy or absence of medical therapy. Examples of said disease states and disorders include bone and cartilage disorders and cardiovascular disease and its associated micro and macro vascular complications including infections and inflammation of all these diseases in combination or without. Advantageously, the amount of arginine silicate inositol complex administered per day is between about 2 mg/Kg body weight to 2,500 mg/Kg body weight or from a low dose to a higher dose to observe normal metabolic functions and healthy and the delivery is parenteral, oral or intravenous or topical by solid or liquid or both.