公开(公告)号：WO2012067577A1

公开(公告)日：2012-05-24

申请号：PCT/SE2011/051378

申请日：2011-11-16

Applicant: DOXA AB ,  HERMANSSON, Leif ,  ALPSTEN, Fredrik

Inventor： HERMANSSON, Leif ,  ALPSTEN, Fredrik

IPC: A61K6/033 ,  A61K6/027 ,  A61K6/06 ,  C04B28/02 ,  C04B28/06 ,  C04B28/18 ,  C04B28/28

CPC classification number: A61L24/02 ,  A61K6/033 ,  A61K6/0637 ,  A61K6/0643 ,  A61L24/001 ,  C04B28/06 ,  C04B28/186 ,  C04B2111/00836 ,  C04B22/126 ,  C04B24/24

Abstract: The present invention relates to chemically bonded ceramic biomaterials, especially a dental material or an implant material. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and/or calcium silicate, and phase(s) to secure apatite formation at a pH close to neutrality. A second binder system -a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste is advantageously added. The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications with the aim of remineralisation, integration and bone repair.

Abstract translation: 本发明涉及化学结合的陶瓷生物材料，特别是牙科材料或植入材料。 主要的粘合剂体系在其水合时形成化学键合的陶瓷，并且包含粉末状的铝酸钙和/或硅酸钙，以及在接近中性的pH下确保磷灰石形成的相。 有利地加入第二粘合剂体系 - 交联有机粘合剂体系，其提供新混合糊料的初始交联。 本发明涉及用于制备本发明化学结合的陶瓷生物材料的粉末组合物，以及形成生物材料的糊料，以及包含粉末状组合物和水合液体的试剂盒，以及牙科中生物材料的方法和用途 和植入应用，目的是再矿化，整合和骨修复。