公开(公告)号：WO2013043640A1

公开(公告)日：2013-03-28

申请号：PCT/US2012/055982

申请日：2012-09-19

Applicant: THE CLEVELAND CLINIC FOUNDATION ,  IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason

Inventor： IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason

IPC: A61B17/17 ,  A61B17/15

CPC classification number: A61B17/15 ,  A61B17/17 ,  A61B2017/568 ,  A61B2034/108 ,  A61F2002/30957 ,  B33Y80/00

Abstract: A method for producing at least one patient-specific surgical aid includes providing a physical model of a native patient tissue. The physical model has at least one surface of interest. A constraining wall is placed in contact with at least a portion of the physical model. A moldable substance is placed into contact with at least a portion of the surface of interest. An impression of the surface of interest is maintained upon the moldable substance. The moldable substance is solidified into a patient- specific surgical aid. The patient-specific surgical aid is removed from the physical model. A system for producing at least one patient- specific surgical aid is also disclosed.

Abstract translation: 用于产生至少一个患者特异性手术辅助的方法包括提供天然患者组织的物理模型。 物理模型至少有一个感兴趣的表面。 约束壁放置成与物理模型的至少一部分接触。 将可模制物质放置成与感兴趣的表面的至少一部分接触。 感兴趣的表面的印象保持在可模制物质上。 可模塑物质固化成患者特异性手术辅助剂。 从物理模型中移除患者特异性外科辅助。 还公开了一种用于生产至少一个患者特异性手术辅助的系统。

公开(公告)号：WO2012058353A1

公开(公告)日：2012-05-03

申请号：PCT/US2011/057954

申请日：2011-10-27

Applicant: THE CLEVELAND CLINIC FOUNDATION ,  IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason, A.

Inventor： IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason, A.

IPC: A61B19/00

CPC classification number: A61B17/88 ,  A61B17/1739 ,  A61B17/1778 ,  A61B17/8872 ,  A61B34/10 ,  A61B2034/107 ,  A61B2034/108 ,  A61B2090/3916

Abstract: A stock instrument (316) includes at least one guide interacting feature. A lower instrument surface of the stock instrument is placed into contact with the patient tissue. A guide (530) has a lower guide surface contoured to substantially mate with at least a portion of an upper instrument surface of the stock instrument. A predetermined instrument orientation upon the patient tissue is defined, which is preselected responsive to preoperative imaging of the patient tissue (100,102). The guide and instrument are mated in a predetermined relative guide/instrument orientation wherein at least one guide interacting feature of the instrument is placed into engagement with at least one instrument guiding feature of the guide. The guide is moved into a predetermined guide orientation with respect to the patient tissue and concurrently the instrument is moved into a predetermined instrument orientation with respect to the patient tissue.

Abstract translation: 股票工具（316）包括至少一个指导交互特征。 存放仪器的较低仪器表面与患者组织接触。 引导件（530）具有较低的引导表面，其轮廓形成为与该库存工具的上部仪器表面的至少一部分基本配合。 定义了患者组织上的预定的仪器取向，其被预先选择为对患者组织（100,102）的术前成像。 导向器和仪器以预定的相对引导/仪器取向配合，其中仪器的至少一个引导器相互作用特征被放置成与引导件的至少一个仪器引导特征接合。 引导件相对于患者组织移动到预定的引导方向，并且同时使器械相对于患者组织移动到预定的仪器取向。

公开(公告)号：WO2012097040A1

公开(公告)日：2012-07-19

申请号：PCT/US2012/020898

申请日：2012-01-11

Applicant: THE CLEVELAND CLINIC FOUNDATION ,  BRYAN, Jason, A. ,  IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K.

Inventor： BRYAN, Jason, A. ,  IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K.

IPC: A61B17/17 ,  A61B19/00

CPC classification number: A61B90/06 ,  A61B17/8897 ,  A61B2090/062 ,  A61B2090/0811

Abstract: A distance indicator (100) for indicating the distance that a device has traveled includes an elongate housing (102) with a guidewire connector (110) configured for operative connection to a guidewire to hold the housing stationary with respect thereto. A plunger (112) is operatively connected to the housing for longitudinal motion with respect to the housing. A first plunger end (114) is configured to operatively contact the device. As the guidewire connector is holding the housing stationary with respect to the guidewire, the first plunger end is placed into operative contact with the device with the plunger and housing in a first relative plunger/housing position. The device moves longitudinally. The plunger moves into a second relative plunger/housing position assisted by the operative connection between the first plunger end and the device. The longitudinal difference between the first and second relative plunger/housing positions indicates a distance that the device has moved longitudinally with respect to the guidewire.

Abstract translation: 用于指示设备行进的距离的距离指示器（100）包括具有导丝连接器（110）的细长壳体（102），该引导线连接器被配置为可操作地连接到导丝，以将壳体相对于其固定。 柱塞（112）可操作地连接到壳体，用于相对于壳体的纵向运动。 第一柱塞端（114）构造成可操作地接触该装置。 由于导丝连接器将壳体相对于导丝固定住，所以第一柱塞端被放置成与装置工作接触，柱塞和壳体处于第一相对柱塞/壳体位置。 设备纵向移动。 柱塞移动到由第一柱塞端和装置之间的操作连接辅助的第二相对柱塞/壳体位置。 第一和第二相对柱塞/壳体位置之间的纵向差表示装置相对于导丝纵向移动的距离。

公开(公告)号：WO2012058353A4

公开(公告)日：2012-06-21

申请号：PCT/US2011057954

申请日：2011-10-27

Applicant: CLEVELAND CLINIC FOUNDATION ,  IANNOTTI JOSEPH P ,  BARSOUM WAEL K ,  BRYAN JASON A

Inventor： IANNOTTI JOSEPH P ,  BARSOUM WAEL K ,  BRYAN JASON A

IPC: A61B19/00

CPC classification number: A61B17/88 ,  A61B17/1739 ,  A61B17/1778 ,  A61B17/8872 ,  A61B34/10 ,  A61B2034/107 ,  A61B2034/108 ,  A61B2090/3916

Abstract: A stock instrument (316) includes at least one guide interacting feature. A lower instrument surface of the stock instrument is placed into contact with the patient tissue. A guide (530) has a lower guide surface contoured to substantially mate with at least a portion of an upper instrument surface of the stock instrument. A predetermined instrument orientation upon the patient tissue is defined, which is preselected responsive to preoperative imaging of the patient tissue (100,102). The guide and instrument are mated in a predetermined relative guide/instrument orientation wherein at least one guide interacting feature of the instrument is placed into engagement with at least one instrument guiding feature of the guide. The guide is moved into a predetermined guide orientation with respect to the patient tissue and concurrently the instrument is moved into a predetermined instrument orientation with respect to the patient tissue.

Abstract translation: 库存仪器（316）包括至少一个引导交互特征。 储备器械的下部器械表面被放置成与患者组织接触。 引导件（530）具有下部引导表面，其被成形为与储备器械的上器械表面的至少一部分基本配合。 定义患者组织上的预定仪器取向，其响应于患者组织（100,102）的术前成像而被预选。 导向器和器械以预定的相对导向器/器械取向匹配，其中器械的至少一个导向器相互作用特征被放置成与导向器的至少一个器械导向特征相接合。 引导件相对于患者组织移动到预定的引导方位，并且同时使器械相对于患者组织移动到预定的器械取向。

公开(公告)号：WO2012058349A2

公开(公告)日：2012-05-03

申请号：PCT/US2011/057949

申请日：2011-10-27

Applicant: THE CLEVELAND CLINIC FOUNDATION ,  IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason, A. ,  O'NEILL, Peter, D.

Inventor： IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason, A. ,  O'NEILL, Peter, D.

IPC: A61B17/17

CPC classification number: A61B17/1778 ,  A61B17/151 ,  A61B17/152 ,  A61B17/1746 ,  A61B34/10 ,  A61B2017/568 ,  A61B2034/104 ,  A61B2034/105 ,  A61B2034/108

Abstract: A patient tissue includes a primary patient tissue area and an anatomically differentiated bordering secondary patient tissue area. An apparatus is at least partially customized responsive to preoperative imaging of the patient tissue. Means are provided for mating with the primary patient tissue area in a preselected relative orientation. Means are provided for fixing a first landmark to the primary patient tissue area in at least one of a predetermined marking location and a predetermined marking trajectory. Means are provided for fixing a second landmark to the secondary patient tissue area in at least one of a predetermined marking location and a predetermined marking trajectory. A method of associating a plurality of landmarks with a patient tissue is also provided.

Abstract translation: 患者组织包括主要患者组织区域和解剖学上分化的毗邻次要患者组织区域。 响应于患者组织的术前成像，至少部分地定制装置。 提供了用于以预选的相对取向与主要患者组织区域配合的装置。 提供了用于在预定标记位置和预定标记轨迹中的至少一个中将第一标记固定到主要患者组织区域的装置。 提供了用于在预定标记位置和预定标记轨迹中的至少一个中将第二标记固定到次级患者组织区域的装置。 还提供了将多个界标与患者组织相关联的方法。

公开(公告)号：WO2013025912A2

公开(公告)日：2013-02-21

申请号：PCT/US2012/051151

申请日：2012-08-16

Applicant: THE CLEVELAND CLINIC FOUNDATION ,  BARSOUM, Wael, K. ,  KATTAN, Michael, W. ,  MORRIS, William, H. ,  JOHNSTON, Douglas, R.

Inventor： BARSOUM, Wael, K. ,  KATTAN, Michael, W. ,  MORRIS, William, H. ,  JOHNSTON, Douglas, R.

IPC: G06Q50/22 ,  G06F3/048

CPC classification number: G06F19/30 ,  G06F19/00 ,  G06F19/328 ,  G06Q10/10 ,  G06Q50/22

Abstract: This disclosure relates to a system (10) that can include memory to store computer executable instructions and enterprise data. The enterprise data can include customer data representing information to document services rendered by a given enterprise provider for each customer. A processor can be configured to access the memory and execute the computer executable instructions. The instructions can include an analytics engine (16) to compute descriptive statistics relating to the services rendered by one or more providers based on customer problems documented by providers in the customer data. Output controls (48) can generate an output of the descriptive statistics.

Abstract translation: 本公开涉及可以包括用于存储计算机可执行指令和企业数据的存储器的系统（10）。 企业数据可以包括表示由给定企业提供商为每个客户呈现的文档服务的信息的客户数据。 可以将处理器配置为访问存储器并执行计算机可执行指令。 指令可以包括分析引擎（16），用于根据客户数据中的提供者记录的客户问题来计算与由一个或多个提供商呈现的服务相关的描述性统计。 输出控件（48）可以生成描述统计的输出。

公开(公告)号：WO2012058355A4

公开(公告)日：2012-07-26

申请号：PCT/US2011057957

申请日：2011-10-27

Applicant: CLEVELAND CLINIC FOUNDATION ,  IANNOTTI JOSEPH P ,  BARSOUM WAEL K ,  BRYAN JASON A ,  O'NEILL PETER D

Inventor： IANNOTTI JOSEPH P ,  BARSOUM WAEL K ,  BRYAN JASON A ,  O'NEILL PETER D

IPC: A61B17/17 ,  A61B19/00

CPC classification number: A61B17/1739 ,  A61B17/1778 ,  A61B34/10 ,  A61B34/25 ,  A61B2017/568 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2/4081 ,  A61F2002/4633

Abstract: A method of preoperative planning and provision of patient-specific surgical aids includes creating a virtual model of a native patient tissue. A virtual device is placed into a predetermined device orientation relative to the virtual model (422) of the native patient tissue. At least one predetermined landmark orientation is specified for placement of at least one virtual landmark relative to the native patient tissue. A virtual patient-specific template containing the predetermined landmark orientation and having a landmark guiding feature is generated. At least one virtual patient-specific placement guide configured to interact simultaneously with at least one previously placed virtual landmark and the virtual device when the virtual device is in the predetermined device orientation is generated. A physical patient-specific template is created as a tangible representation of the virtual patient-specific template. A physical patient-specific placement guide is created as a tangible representation of the virtual patient-specific placement guide.

Abstract translation: 术前规划和提供患者特异性手术辅助装置的方法包括创建本地患者组织的虚拟模型。 将虚拟设备相对于本机患者组织的虚拟模型（422）放置成预定的设备方位。 为至少一个虚拟地标相对于本机患者组织的放置指定至少一个预定的标记取向。 生成包含预定的标记取向并具有地标引导特征的虚拟患者特定模板。 至少一个虚拟患者特定的放置引导件被配置为当虚拟设备处于预定的设备取向时与至少一个先前放置的虚拟地标和虚拟设备同时交互。 创建具体的患者特定模板作为虚拟患者特定模板的有形表示。 身体特定的物理位置指南被创建为虚拟患者特定放置指南的有形表示。

公开(公告)号：WO2012155015A4

公开(公告)日：2013-01-10

申请号：PCT/US2012037445

申请日：2012-05-11

Applicant: CLEVELAND CLINIC FOUNDATION ,  BARSOUM WAEL K ,  KATTAN MICHAEL W ,  MORRIS WILLIAM H ,  JOHNSTON DOUGLAS R

Inventor： BARSOUM WAEL K ,  KATTAN MICHAEL W ,  MORRIS WILLIAM H ,  JOHNSTON DOUGLAS R

IPC: G06F19/00

CPC classification number: G16H15/00 ,  G16H10/60

Abstract: This disclosure relates to a visualizatton tool that can be implemented to facilitate medicai decision making by providing an interactive graphical map of relevant health data. The interactive map can include graphical elements representing health data that can be obtained from an EHR and associations between such data that are represented by graphical connections. The graphical elements and associations can be modified to reflect medical decision making.

Abstract translation: 本公开涉及一种可视化工具，其可以通过提供相关健康数据的交互式图形图来实现以便于药物决策。 交互式地图可以包括表示可以从EHR获得的健康数据的图形元素以及由图形连接表示的这些数据之间的关联。 可以修改图形元素和关联，以反映医学决策。

公开(公告)号：WO2012058344A1

公开(公告)日：2012-05-03

申请号：PCT/US2011/057944

申请日：2011-10-27

Applicant: THE CLEVELAND CLINIC FOUNDATION ,  IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason, A.

Inventor： IANNOTTI, Joseph, P. ,  BARSOUM, Wael, K. ,  BRYAN, Jason, A.

IPC: A61B17/17 ,  A61B17/90 ,  A61B19/00 ,  A61F2/34 ,  A61B17/88

CPC classification number: A61B17/1728 ,  A61B17/1746 ,  A61B17/1753 ,  A61B17/1778 ,  A61B17/8061 ,  A61B17/8897 ,  A61B34/10 ,  A61B2017/00526 ,  A61B2017/568 ,  A61B2017/90 ,  A61F2/34 ,  A61F2/4609 ,  A61F2002/3401 ,  A61F2002/3403 ,  A61F2002/3408

Abstract: A guide for assisting with attachment of a stock prosthetic implant to a patient tissue includes a lower guide surface configured to contact an upper implant surface of the stock prosthetic implant when a lower implant surface of the stock prosthetic implant contacts the patient tissue. An upper guide surface is accessible to a user when the lower guide surface is in contact with the upper implant surface. At least one guiding aperture extends through the guide body between the upper and lower guide surfaces at a predetermined aperture location with respect to the guide body and defines a predetermined target trajectory through the guide body. At least one of the target trajectory and the aperture location of each guiding aperture is preselected responsive to preoperative imaging of the patient tissue. A method of assisting with attachment of a stock prosthetic implant to a patient tissue is also provided.

Abstract translation: 用于辅助将股票假体植入物附着到患者​​组织的引导件包括下部引导表面，所述下部引导表面构造成当股票假体植入物的下部植入物表面接触患者组织时接触股票假体植入物的上部植入物表面。 当下引导表面与上植入物表面接触时，使用者可以访问上引导表面。 至少一个引导孔在相对于引导体的预定孔位置处延伸穿过上引导表面和下引导表面之间的引导体，并且通过引导体限定预定的目标轨迹。 响应于患者组织的术前成像，预先选择每个引导孔的目标轨迹和孔位置中的至少一个。 还提供了一种辅助将股票假体植入物附着到患者​​组织的方法。

公开(公告)号：WO2013025912A3

公开(公告)日：2013-04-25

申请号：PCT/US2012051151

申请日：2012-08-16

Applicant: CLEVELAND CLINIC FOUNDATION ,  BARSOUM WAEL K ,  KATTAN MICHAEL W ,  MORRIS WILLIAM H ,  JOHNSTON DOUGLAS R

Inventor： BARSOUM WAEL K ,  KATTAN MICHAEL W ,  MORRIS WILLIAM H ,  JOHNSTON DOUGLAS R

IPC: G06Q50/22 ,  G06F3/048

CPC classification number: G06F19/30 ,  G06F19/328 ,  G06Q10/10 ,  G06Q50/22

Abstract: This disclosure relates to a system (10) that can include memory to store computer executable instructions and enterprise data. The enterprise data can include customer data representing information to document services rendered by a given enterprise provider for each customer. A processor can be configured to access the memory and execute the computer executable instructions. The instructions can include an analytics engine (16) to compute descriptive statistics relating to the services rendered by one or more providers based on customer problems documented by providers in the customer data. Output controls (48) can generate an output of the descriptive statistics.

Abstract translation: 本公开涉及可以包括存储器以存储计算机可执行指令和企业数据的系统（10）。 企业数据可以包括表示信息的客户数据，以记录给定企业提供商为每个客户提供的服务。 处理器可以被配置为访问存储器并执行计算机可执行指令。 该指令可以包括分析引擎（16），以基于由客户数据中的提供者记录的客户问题来计算与由一个或多个提供者提供的服务有关的描述性统计。 输出控件（48）可以生成描述性统计信息的输出。