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    ION SOURCE WITH DEVICE FOR OXIDISING OR HALOGENATING A SAMPLE
    1.
    发明申请
    ION SOURCE WITH DEVICE FOR OXIDISING OR HALOGENATING A SAMPLE 审中-公开
    离子源与设备用于氧化或降解样品

    公开(公告)号：WO2010007368A3

    公开(公告)日：2010-09-10

    申请号：PCT/GB2009001753

    申请日：2009-07-16

    Applicant: MICROMASS LTD ,  BATEMAN ROBERT HAROLD

    Inventor： BATEMAN ROBERT HAROLD

    IPC: H01J27/02 ,  G01N31/12 ,  H01J49/14

    CPC classification number: H01J49/147 ,  H01J27/02 ,  H01J49/0077

    Abstract: An ion source is disclosed wherein a sample is introduced into the sample chamber (1) of the ion source in the gas phase via a sample introduction capillary tube (2). The sample is directed onto a heated surface (6) coated with an oxidising reagent such as copper oxide. Carbon in the sample is oxidised to form carbon dioxide. The resulting carbon dioxide molecules are then ionised by electron impact ionisation with an electron beam (3) and the resulting ions are passed to a mass analyser for mass analysis.

    Abstract translation: 公开了一种离子源，其中将样品通过样品导入毛细管（2）引入到气相中的离子源的样品室（1）中。 样品被引导到涂覆有氧化剂如氧化铜的加热表面（6）上。 样品中的碳被氧化形成二氧化碳。 然后用电子束（3）通过电子轰击电离将所得二氧化碳分子电离，并将所得离子通过质量分析器进行质量分析。

    MASS SPECTROMETER
    3.
    发明申请
    MASS SPECTROMETER 审中-公开
    质谱仪

    公开(公告)号：WO2008102155A2

    公开(公告)日：2008-08-28

    申请号：PCT/GB2008/000617

    申请日：2008-02-21

    Applicant: MICROMASS UK LIMITED ,  BATEMAN, Robert, Harold ,  GREEN, Martin ,  WILDGOOSE, Jason, Lee

    Inventor： BATEMAN, Robert, Harold ,  GREEN, Martin ,  WILDGOOSE, Jason, Lee

    IPC: H01J49/42

    CPC classification number: H01J49/0095 ,  H01J49/423 ,  H01J49/424

    Abstract: A mass spectrometer is disclosed comprising a 2D or 3D ion trap. The 2D ion trap comprises a quadrupole rod set ion trap wherein a slot is provided in each of the rods 1 to allow ions to be ejected radially from the ion trap. The 3D ion trap comprises a central ring electrode which is radially segmented and wherein a slot is provided in each radial segment to allow ions to be ejected radially from the ion trap. Ions having different mass to charge ratios and/or opposite polarities may be simultaneously ejected from the ion trap via different exit pathways.

    Abstract translation: 公开了包括2D或3D离子阱的质谱仪。 2D离子阱包括四极棒组离子阱，其中在每个棒1中设置槽，以允许离子从离子阱径向喷射。 3D离子阱包括径向分段的中心环电极，并且其中在每个径向段中设置狭槽以允许离子从离子阱径向喷射。 具有不同质荷比和/或相反极性的离子可以通过不同的出口通道从离子阱同时喷出。

    MASS SPECTROMETER
    4.
    发明申请
    MASS SPECTROMETER 审中-公开
    质谱仪

    公开(公告)号：WO2008047101A2

    公开(公告)日：2008-04-24

    申请号：PCT/GB2007003937

    申请日：2007-10-16

    Applicant: MICROMASS LTD ,  KENNY DANIEL JAMES ,  BATEMAN ROBERT HAROLD ,  GREEN MARTIN ,  WILDGOOSE JASON LEE ,  PRINGLE STEVEN DEREK

    Inventor： KENNY DANIEL JAMES ,  BATEMAN ROBERT HAROLD ,  GREEN MARTIN ,  WILDGOOSE JASON LEE ,  PRINGLE STEVEN DEREK

    CPC classification number: H01J49/005 ,  H01J49/0031 ,  H01J49/004 ,  H01J49/0045 ,  H01J49/065 ,  H01J49/34 ,  H01J49/4235

    Abstract: A collision or fragmentation cell (4) is disclosed comprising a plurality of electrodes wherein a first RF voltage (7a) is applied to an upstream group of electrodes and a second different RF voltage (7b) is applied to a downstream group of electrodes. The radial confinement of parent ions entering the collision or fragmentation cell (4) is optimised by the first RF voltage applied to the upstream group of electrodes and the radial confinement of daughter or fragment ions produced within the collision or fragmentation cell (4) is optimised by the second different RF voltage applied to the downstream group of electrodes.

    Abstract translation: 公开了一种碰撞或分裂单元（4），其包括多个电极，其中将第一RF电压（7a）施加到上游电极组，并且将第二不同RF电压（7b）施加到下游组电极。 通过施加到上游电极组的第一RF电压来优化进入碰撞或破碎电池（4）的母体离子的径向约束，并且优化在碰撞或断裂电池（4）内产生的子或碎片离子的径向约束 通过施加到下游组电极的第二不同RF电压。

    MASS SPECTROMETER
    7.
    发明申请
    MASS SPECTROMETER 审中-公开
    质谱分析仪

    公开(公告)号：WO2006059123A8

    公开(公告)日：2007-04-12

    申请号：PCT/GB2005004627

    申请日：2005-12-02

    Applicant: MICROMASS LTD ,  BATEMAN ROBERT HAROLD ,  GILES KEVIN ,  PRINGLE STEVEN DEREK

    Inventor： BATEMAN ROBERT HAROLD ,  GILES KEVIN ,  PRINGLE STEVEN DEREK

    IPC: H01J49/42 ,  H01J49/40

    CPC classification number: H01J49/065

    Abstract: An ion guide (7a) is disclosed comprising one or more layers of intermediate planar, plate or mesh electrodes (2). A first array of first electrodes (8a-8e) is provided on an upper surface and a second array of second electrodes (9a-9e) is arranged on a lower surface. An ion guiding region is formed within the ion guide (7a). One or more transient DC voltages or potentials are preferably applied to the first and second array of second electrodes (8a-8e, 9a-9e) in order to urge, propel, force or accelerate ions through or along the ion guide (7a).

    Abstract translation: 公开了一种离子导向器（7a），其包括一个或多个中间平面，平板或网状电极（2）的层。 第一电极阵列（8a-8e）设置在上表面上，第二电极阵列（9a-9e）设置在下表面上。 在离子引导件（7a）内形成离子引导区域。 优选将一个或多个瞬态DC电压或电势施加到第二电极（8a-8e，9a-9e）的第一阵列和第二阵列以促使，推动，迫使或加速离子通过或沿着离子导向器（7a）。

    CHARGED-PARTICLE ENERGY ANALYZER AND MASS SPECTROMETER INCORPORATING IT
    8.
    发明申请
    CHARGED-PARTICLE ENERGY ANALYZER AND MASS SPECTROMETER INCORPORATING IT 审中-公开
    充电粒子能量分析仪和质谱仪

    公开(公告)号：WO1990015434A1

    公开(公告)日：1990-12-13

    申请号：PCT/GB1990000845

    申请日：1990-06-01

    Applicant: VG INSTRUMENTS GROUP LIMITED ,  BATEMAN, Robert, Harold

    Inventor： VG INSTRUMENTS GROUP LIMITED

    IPC: H01J49/48

    CPC classification number: H01J49/48 ,  H01J49/025 ,  H01J49/326

    Abstract: An electrostatic analyzer (1) for dispersing a beam of charged particles (10) according to their energy comprises two groups (2, 3) of spaced-apart linear electrodes (4, 8, 9, 20) respectively disposed above and below the charged particle beam. The potentials of the electrodes (4, 8, 9, 20) in each group progressively increase from one to the next, thereby providing an electrostatic field in a central plane (7) between the groups which is capable of deflecting the charged particles along different curved trajectories (11, 12) according to their energies. Various mass spectrometers incorporating such an analyzer are also disclosed.

    Abstract translation: 用于根据其能量分散带电粒子束（10）的静电分析器（1）包括分别设置在带电的上方和下方的分隔开的线性电极（4,8,9,20）的两组（2,3） 粒子束。 每个组中电极（4,8,9,20）的电位从一个逐渐增加到另一组，从而在组之间的中心平面（7）中提供静电场，该静电场能够使带电粒子沿不同的方向偏转 弯曲轨迹（11,12）根据其能量。 还公开了包含这种分析仪的各种质谱仪。

    MASS SPECTROMETER
    9.
    发明申请
    MASS SPECTROMETER 审中-公开
    质谱仪

    公开(公告)号：WO2007060421A3

    公开(公告)日：2008-05-08

    申请号：PCT/GB2006004362

    申请日：2006-11-23

    Applicant: MICROMASS LTD ,  BATEMAN ROBERT HAROLD

    Inventor： BATEMAN ROBERT HAROLD

    IPC: H01J49/42

    CPC classification number: B82Y30/00 ,  H01J49/0031 ,  H01J49/0045 ,  H01J49/0068

    Abstract: A method of mass spectrometry is disclosed wherein an Electron Capture Dissociation, Electron Transfer Dissociation or Surface Induced Dissociation fragmentation device is repeatedly switched between a high fragmentation or reaction mode and a low fragmentation or reaction mode. Parent ions from a first sample are passed through the device and parent ion mass spectra and fragmentation ion mass spectra are obtained. Parent ions from a second sample are then passed through the device and a second set of parent ion mass spectra and fragmentation ion mass spectra are obtained. The mass spectra are then compared and if either certain parent ions or certain fragmentation ions in the two samples are expressed differently then further analysis is performed to seek to identify the ions which are expressed differently in the two different samples.

    Abstract translation: 公开了一种质谱法，其中电子俘获解离，电子转移解离或表面诱导的解离断裂装置在高分裂或反应模式与低碎裂或反应模式之间重复切换。 来自第一个样品的亲本离子通过器件，并获得亲本离子质谱和碎片离子质谱。 然后将来自第二个样品的母离子通过该装置，并获得第二组母离子质谱和碎裂离子质谱。 然后比较质谱，并且如果两个样品中的某些亲本离子或某些断裂离子不同地表达，则进行进一步分析以寻找在两个不同样品中不同表达的离子。

    MASS SPECTROMETER
    10.
    发明申请
    MASS SPECTROMETER 审中-公开
    质谱仪

    公开(公告)号：WO2007148115A2

    公开(公告)日：2007-12-27

    申请号：PCT/GB2007/002346

    申请日：2007-06-25

    Applicant: MICROMASS UK LIMITED ,  BATEMAN, Robert, Harold ,  GILES, Kevin ,  PRINGLE, Steven, Derek ,  WILDGOOSE, Jason, Lee

    Inventor： BATEMAN, Robert, Harold ,  GILES, Kevin ,  PRINGLE, Steven, Derek ,  WILDGOOSE, Jason, Lee

    CPC classification number: H01J49/429 ,  G01N27/622 ,  H01J49/0031 ,  H01J49/004

    Abstract: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (6) arranged upstream of a collision or fragmentation cell (8). Ions are separated according to their ion mobility within the ion mobility spectrometer or separator (6). The kinetic energy of the ions exiting the ion mobility spectrometer or separator (6) is increased substantially linearly with time in order to optimise the fragmentation energy of ions as they enter the collision or fragmentation cell (8). During the time that the potential of the ion mobility spectrometer or separator (6) is being varied, the potential of ion-optical components upstream of the ion mobility spectrometer or separator (6) such as an ion source (1), ion guide (2), quadrupole mass filter (3), optional second collision or fragmentation cell (4) and an ion trapping device (5) are kept constant.

    Abstract translation: 公开了一种质谱仪，其包括设置在碰撞或破碎电池（8）上游的离子迁移谱仪或分离器（6）。 根据离子迁移谱仪或分离器（6）内的离子迁移率分离离子。 离子离子迁移谱仪或分离器（6）离子的动能随着时间的推移基本线性地增加，以优化离子进入碰撞或破碎电池（8）时的碎裂能。 在离子迁移谱仪或分离器（6）的电位变化的时间内，离子迁移谱仪或分离器（6）上游离子光学部件的离子源（1），离子导向器 2），四极质量过滤器（3），任选的第二碰撞或碎裂单元（4）和离子捕获装置（5）保持恒定。

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