公开(公告)号：WO2008064130A2

公开(公告)日：2008-05-29

申请号：PCT/US2007/085001

申请日：2007-11-16

Applicant: BLOOM, Matthew, B. ,  STERLING, Bernhard, B.

Inventor： BLOOM, Matthew, B. ,  STERLING, Bernhard, B.

IPC: A61B5/00

CPC classification number: A61B5/0075 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/444 ,  A61B5/445 ,  A61B5/7275 ,  G01N21/35

Abstract: Disclosed are methods of determining long-term deposition pattern of a compound in tissue. The following steps can be followed: placing tissue against a receptor; directing mid- infrared electromagnetic radiation onto the tissue; quantifying the electromagnetic radiation that is reflected from the tissue to obtain a reflected amount; using a calibration equation to calculate the concentration of a compound from the reflected amount; and using the concentration of the compound to evaluate presence of a clinical condition in the tissue.

Abstract translation: 公开了确定组织中化合物的长期沉积模式的方法。 可以遵循以下步骤：将组织置于受体上; 将中红外电磁辐射引导到组织上; 量化从组织反射的电磁辐射以获得反射量; 使用校正方程从反射量计算化合物的浓度; 并使用化合物的浓度来评估组织中临床状况的存在。

公开(公告)号：WO2008064130A3

公开(公告)日：2008-08-14

申请号：PCT/US2007085001

申请日：2007-11-16

Applicant: BLOOM MATTHEW B ,  STERLING BERNHARD B

Inventor： BLOOM MATTHEW B ,  STERLING BERNHARD B

IPC: A61B5/00 ,  G01N21/35

CPC classification number: A61B5/0075 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/444 ,  A61B5/445 ,  A61B5/7275 ,  G01N21/35

Abstract: Disclosed are methods of determining long-term deposition pattern of a compound in tissue. The following steps can be followed: placing tissue against a receptor; directing mid- infrared electromagnetic radiation onto the tissue; quantifying the electromagnetic radiation that is reflected from the tissue to obtain a reflected amount; using a calibration equation to calculate the concentration of a compound from the reflected amount; and using the concentration of the compound to evaluate presence of a clinical condition in the tissue.

Abstract translation: 公开了确定组织中化合物的长期沉积模式的方法。 可以遵循以下步骤：将组织贴靠在受体上; 将中红外电磁辐射引导到组织上; 量化从组织反射的电磁辐射以获得反射量; 使用校准方程从反射量计算化合物的浓度; 并使用该化合物的浓度来评估组织中临床病症的存在。