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1.发明申请
公开(公告)号：WO2019115670A1
公开(公告)日：2019-06-20
申请号：PCT/EP2018/084686
申请日：2018-12-13
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： ESPINA PEREZ, Javier , WORTELBOER, Pippinus, Maarten, Robertus , GERHARDT, Lutz, Christian , VAN LIESHOUT, Ron, Martinus, Laurentius , JOHNSON, Mark, Thomas
CPC classification number: A61B5/150022 , A61B5/0051 , A61B5/14514 , A61B5/14532 , A61B5/1455 , A61B5/150076 , A61B5/150083 , A61B5/150091 , A61B5/150099 , A61B5/150389 , A61B5/150511 , A61B5/150755 , A61B5/150862 , A61B5/150877 , A61B5/150946 , A61B5/150969 , A61B5/150984 , A61B5/155 , A61B5/157 , A61B5/6802 , A61B5/7475 , A61M2037/003
Abstract: The present disclosure is directed to wearable or insertable devices that allow for ongoing sampling and analysis of biomarkers and self-cleaning. In various embodiments, an apparatus may include a base (102) defining at least one reservoir (104), and at least one microneedle (106, 306, 406, 506, 606, 706, 806, 906) extending from the base. The at least one microneedle may define an inner lumen (409, 509, 609, 709, 809, 909) that fluidly couples the at least one reservoir with tissue of the patient. A mechanically responsive material (670, 770, 870) on an inner surface of the at least one microneedle defining the inner lumen may be reactive to various stimuli to undergo various mechanical responses, such as one mechanical response that purges fluid from the inner lumen of the at least one microneedle and another mechanical response that draws fluid into the inner lumen of the at least one microneedle.
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公开(公告)号：WO2019099052A1
公开(公告)日：2019-05-23
申请号：PCT/US2017/062834
申请日：2017-11-21
Applicant: OJAI RETINAL TECHNOLOGY, LLC
Inventor： LUTTRULL, Jeffrey K. , CHANG, David B.
IPC: A61B3/12
CPC classification number: A61B3/12 , A61B3/0008 , A61B5/0066 , A61B5/0082 , A61B5/14546 , A61B5/1455 , A61F9/00821 , A61F2009/00863
Abstract: A process for determining levels or concentrations of melanin within an eye includes generating first and second light beams of a different wavelength. The first and second light beams are applied into the eye, such as a retinal pigment epithelium and choroid of the eye. The amount of light reflected from the eye from the first light beam and the second light beam is measured, such as using a reflectometer. A level or concentration of the melanin within the eye is calculated using the measured amount of light reflected from the eye from the first and second light beams.
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公开(公告)号：WO2019010552A1
公开(公告)日：2019-01-17
申请号：PCT/BR2017/050251
申请日：2017-08-29
Applicant: MISTRORIGO DE ALMEIDA, Tácito
Inventor： MISTRORIGO DE ALMEIDA, Tácito
IPC: A61B5/145
CPC classification number: A61B5/145 , A61B5/1455
Abstract: Disposição construtiva em oxímetro portátil para uso contínuo, compreendendo um invólucro bipartido (11) formando uma pinça consistindo de uma primeira (13) e uma segunda partes (14), configuradas de modo a encerrar entre si a extremidade do dedo (12) do paciente quando fechada, onde dita fixação é provida pela sobreposição, ao dito dedo (12), de um prolongamento (15) em forma de meia-cana provido na extremidade proximal de dita primeira parte (13), e por uma cinta (16) provida de meios semipermanentes de retenção envolvendo o dedo (12) juntamente com o dito prolongamento (15), a pressão (18) de fechamento entre ditas primeira parte (13) e segunda parte (14) do invólucro sendo provida por molas (17) unindo ditas primeira e segunda partes entre si.
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公开(公告)号：WO2019010348A1
公开(公告)日：2019-01-10
申请号：PCT/US2018/040979
申请日：2018-07-06
Applicant: THE JOHNS HOPKINS UNIVERSITY
Inventor： PATHAK, Arvind , THAKOR, Nitish , SENARATHNA, Janaka , YU, Hang
CPC classification number: A61B1/00 , A61B5/0042 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0261 , A61B5/1455 , A61B5/489 , G02B21/0008 , G02B21/082 , G02B21/16
Abstract: An embodiment in accordance with the present invention provides a miniature microscope capable of performing in vivo, real-time imaging of multiple organ sites in awake and behaving animals (e.g. rodents). A microscope according to the present invention includes multiple optical contrast mechanisms (i.e. contrast arising from neural, hemodynamic and other physiological components). Exemplary contrast mechanisms include, but are not limited to fluorescence, hemoglobin level, deoxyhemoglobin level, and blood flow. The microscope is fully adaptable to in vitro and ex vivo imaging, can be customized to concurrently image at variable magnifications, conduct optogenetic/electrical/chemical stimulations, drug delivery, microdialysis, accompanied by electrical signal recording, wireless image transmission and charging.
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公开(公告)号：WO2018217066A1
公开(公告)日：2018-11-29
申请号：PCT/KR2018/005985
申请日：2018-05-25
Applicant: 삼성전자 주식회사
IPC: A61B5/00 , A61B5/024 , A61B5/1455 , A61B5/021
CPC classification number: A61B5/00 , A61B5/021 , A61B5/024 , A61B5/1455
Abstract: 본 발명의 다양한 실시 예에 따른 전자 장치는, 생체 신호를 획득하기 위한 센서, 및 프로세서를 포함하고, 상기 프로세서는, 상기 센서를 이용하여, 생체 신호를 획득하고, 상기 생체 신호의 제1부분에 적어도 기반하여 제1생체 정보를 측정하고, 상기 제1부분의 적어도 일부인 제2부분에 적어도 기반하여 제2생체 정보를 측정하고, 및 상기 제1생체 정보 또는 상기 제2생체 정보 중 적어도 하나를 상기 전자 장치와 기능적으로 연결된 디스플레이를 이용하여 표시하도록 설정될 수 있다.
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Patent Agency Ranking
公开(公告)号：WO2018214299A1
公开(公告)日：2018-11-29
申请号：PCT/CN2017/098191
申请日：2017-08-19
Applicant: 深圳市前海安测信息技术有限公司
IPC: A61B5/1455
CPC classification number: A61B5/1455
Abstract: 一种无创血糖数据采集装置（01），包括信号采集器（1）和信号处理电路（2）。信号采集器（1）包括支撑架（10）、上检测板（11）、下检测板（12）、红外光源（13）和光电传感器（14）。支撑架（10）的上端设置有滑动槽（100），上检测板（11）的一端设置在滑动槽（100）内，下检测板（12）固定在支撑架（10）的下端；下检测板（12）的上表面设有铰链机构（16），铰链机构（16）固定在下检测板（12）的上表面；上检测板（11）位于铰链机构（16）的正上方位置处开设有螺孔（110），铰链机构（16）的上端固定有螺杆（111），螺杆（111）的一端固定在铰链机构（16）的上端，螺杆（111）的另一端穿过螺孔（110）且外露于上检测板（11）的上表面；红外光源（13）嵌于上检测板（11）的前端下表面；光电传感器（14）嵌于下检测板（12）的前端上表面。该无创血糖数据采集装置（01）能够高效快速且准确地采集到被检测者的血糖数据，减轻了被检测者采集血液的痛苦。
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公开(公告)号：WO2018192257A1
公开(公告)日：2018-10-25
申请号：PCT/CN2017/118153
申请日：2017-12-23
Applicant: 深圳市前海安测信息技术有限公司
IPC: A61B5/1455
CPC classification number: A61B5/1455 , G04B47/06 , G04G21/02 , G04G21/04
Abstract: 一种无创型具有血糖数据采集功能的腕表（100），包括表盘本体（101）、表带（102）、按钮（103），表带（102）安装在表盘本体（101）的两侧，腕表（100）还包括通过线路连接的红外光发射模块（104）、红外光接收模块（105）、信号转换模块（106）、通讯模块（107）、微控制器（109）和电源模块（110）；红外光发射模块（104）、信号转换模块（106）、通讯模块（107）、微控制器（109）和电源模块（110）设置于表盘本体（101）内，红外光接收模块（105）设置于表带（102）中：按钮（103）设置于表盘本体（101）的外侧，按钮（103）通过线路与微控制器（109）连接。本腕表（100）便于使用者随身使用，能够方便地无创采集用户的人体血糖浓度，提高便携性，提高用户体验。
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公开(公告)号：WO2018159191A1
公开(公告)日：2018-09-07
申请号：PCT/JP2018/002945
申请日：2018-01-30
Applicant: アルプス電気株式会社
IPC: A61B5/02 , A61B5/1455
CPC classification number: A61B5/02 , A61B5/1455
Abstract: 【課題】センサ本体を生体表面に押す力を適切な範囲に調整することが容易であり、長時間の連続装着に適しており、かつ、測定精度の低下を招く測定時における光の混入が抑制された生体情報取得装置を提供すること。【解決手段】生体情報取得装置（１）は、生体表面に発光するとともに、前記生体表面を経由した光を受光する測定部を有する生体センサ（２）と、生体センサ（２）を前記生体に装着するバンド（３）と、を備えており、前記バンド（３）が、生体センサ（２）を取り付け可能な取付部（９）と、取付部（９）に取り付けられた生体センサ（２）を覆う弾性体（８）とを有しており、弾性体（８）の弾性力によって、生体情報を測定可能な位置に生体センサ（２）を保持する。
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公开(公告)号：WO2018151150A1
公开(公告)日：2018-08-23
申请号：PCT/JP2018/005072
申请日：2018-02-14
Applicant: メディカルフォトニクス株式会社
Inventor： 飯永 一也
IPC: A61B5/1455 , G01N21/17
CPC classification number: A61B5/1455 , G01N21/17
Abstract: 【課題】 吸収散乱複合体において、散乱係数を精度よく計測する。 【解決手段】 生体外から生体内に向けて、第１の照射強度で第１の波長の光を照射する第１の照射部と、生体外から生体内に向けて第２の照射強度で第２の波長の光を照射する第２の照射部と、第１の照射部による光の照射位置から第１の距離をあけた第１の検出位置における、生体から放出された第１の波長の光の第１の受光強度を検出する第１の光強度検出部と、第２の照射部による光の照射位置から第２の距離をあけた第２の検出位置における、生体から放出された第２の波長の光の第２の受光強度を検出する第２の光強度検出部と、第２の受光強度に基づき吸収係数を算出し、第１の受光強度と吸収係数に基づき生体内における光の散乱係数を算出し、算出された光の散乱係数に基づき生体内における散乱体濃度を算出する制御部とを有する。
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公开(公告)号：WO2018067585A1
公开(公告)日：2018-04-12
申请号：PCT/US2017/054965
申请日：2017-10-03
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
Inventor： LIN, Anne , LIU, Wentai , LO, Yi-Kai , BENHARASH, Peyman
IPC: A61B5/00 , A61B5/0402 , A61B5/024 , A61B5/1455 , A61B5/021 , A61B5/053
CPC classification number: A61B5/0402 , A61B5/00 , A61B5/0006 , A61B5/021 , A61B5/024 , A61B5/0404 , A61B5/053 , A61B5/1455 , A61B5/7275 , G16H40/67 , G16H50/30
Abstract: Real-time post-operative or post-admission patient monitoring apparatus configured for predicting the type and risk of one or more complications. A remote patient monitoring system (RPMS) performs multi-modality patient sensing, which can include, but is not limited to: EKG and arrhythmia, bio-impedance, skin conductance, SpO 2 and photoplethysmogram (PPG), patient sounds, blood pressure (BP), temperature, white blood cell count, accelerometer, range of motion, and other patient conditions. Based on this information and a database, RPMS compiles patient risk factors following a procedure / operation / admission, and communicates information to health care providers with instructions back to the patient toward increasing patient care and reducing complications.
Abstract translation: 配置用于预测一种或多种并发症的类型和风险的实时手术后或入院后患者监测装置。 远程病人监护系统（RPMS）执行多模态病人感测，其可以包括但不限于：EKG和心律失常，生物阻抗，皮肤电导，SpO 2和光电容积描记法（PPG） ，患者声音，血压（BP），温度，白细胞计数，加速度计，运动范围和其他患者状况。 基于这些信息和数据库，RPMS根据手术/手术/入院编制患者危险因素，并将信息传达给卫生保健提供者，并向患者反馈指导，以增加患者护理并减少并发症。
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