公开(公告)号：WO2011003019A9

公开(公告)日：2011-03-10

申请号：PCT/US2010040818

申请日：2010-07-01

Applicant: CORREX INC ,  BEANE RICHARD M ,  BROWN JOHN W ,  CRUNKLETON JAMES ALAN ,  GAMMIE JAMES S ,  LIEPERT ANTHONY G ,  SMITH JOSEPH L JR

Inventor： BEANE RICHARD M ,  BROWN JOHN W ,  CRUNKLETON JAMES ALAN ,  GAMMIE JAMES S ,  LIEPERT ANTHONY G ,  SMITH JOSEPH L JR

IPC: A61F2/06

CPC classification number: A61F2/2418 ,  A61B17/11 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/06 ,  A61F2/064 ,  A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2002/061 ,  A61F2002/065 ,  A61M25/09 ,  A61M25/10 ,  A61M2025/1052

Abstract: A connector for joining a first hollow structure to the side wall of a second hollow structure, the connector comprising a fluid-constraining tube having a fluid-constraining neck extending therefrom, wherein the tube comprises a lumen having a first opening and a second opening and the neck comprises a lumen having a first opening and a second opening, the neck being joined to the tube so that the neck is in fluid communication with the tube intermediate the length of the tube, such that fluid entepng the first opening of the tube can exit the second opening of the tube, and fluid entenng the first opening of the neck can exit the second opening of the tube at least the portions of the tube adjacent to the first opening of the tube and the second opening of the tube being biased radially outwardly so that they normally assume a radially-expanded configuration.

Abstract translation: 1.一种用于将第一中空结构连接到第二中空结构的侧壁的连接器，所述连接器包括流体约束管，所述流体约束管具有从其延伸的流体约束颈部，其中所述管包括具有第一开口和第二开口的管腔，以及 所述颈部包括具有第一开口和第二开口的内腔，所述颈部结合到所述管，使得所述颈部与所述管在所述管的长度中间流体连通，使得流体进入所述管罐的所述第一开口 离开管的第二开口，并且流体输入颈部的第一开口可离开管的第二开口，至少邻近管的第一开口的管的部分和管的第二开口径向偏置 向外，使得它们通常呈现径向扩展配置。

公开(公告)号：WO2009042816A2

公开(公告)日：2009-04-02

申请号：PCT/US2008/077760

申请日：2008-09-25

Applicant: CORREX, INC. ,  BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, Alan ,  GAMMIE, James, S. ,  SMITH, Joseph, L.

Inventor： BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, Alan ,  GAMMIE, James, S. ,  SMITH, Joseph, L.

IPC: A61B17/11

CPC classification number: A61B17/3423 ,  A61B17/0293 ,  A61B17/11 ,  A61B17/32 ,  A61B17/320016 ,  A61B17/32053 ,  A61B17/3468 ,  A61B2017/00252 ,  A61B2017/1107

Abstract: The invention provides an applicator for forming a hole in a wall of a hollow organ and for connecting a hemostatic connection assembly to the hollow organ, wherein, when the hole is formed in the wall of the hollow organ, a first fluid seal exists between the hemostatic connection assembly and the wall of the hollow organ and a second fluid seal exists between the hemostatic connection assembly and the applicator, thereby minimizing fluid loss from the hollow organ. The invention further provides a hemostatic connection assembly for connecting an inlet conduit to a hollow organ, the hemostatic connection assembly comprising a organ wall connection portion, a cuff portion, an extension portion, and a seal ring portion, wherein, during the process of connecting the inlet conduit to the hollow organ, a first fluid seal exists between the organ wall connection portion and the wall of the hollow organ, and a second fluid seal exists between the hemostatic connection assembly and the inlet conduit, thereby minimizing fluid loss from the hollow organ. A method is also disclosed in which the applicator and hemostatic connection assemblies of the invention are used to connect an inlet conduit to a hollow organ.

Abstract translation: 本发明提供了一种用于在中空器官的壁中形成孔并用于将止血连接组件连接到中空器官的施用器，其中当孔形成在中空器官的壁中时，第一流体密封件存在于 止血连接组件和中空器官的壁和第二流体密封件存在于止血连接组件和施用器之间，从而使来自中空器官的流体损失最小化。 本发明还提供了一种用于将入口导管连接到中空器官的止血连接组件，所述止血连接组件包括器官壁连接部分，箍部分，延伸部分和密封环部分，其中，在连接过程中 到中空器官的入口导管，在器官壁连接部分和中空器官的壁之间存在第一流体密封，并且在止血连接组件和入口导管之间存在第二流体密封，从而使从中空器件的流体损失最小化 器官。 还公开了一种方法，其中本发明的施用器和止血连接组件用于将入口导管连接到中空器官。

公开(公告)号：WO2007081418A1

公开(公告)日：2007-07-19

申请号：PCT/US2006/040230

申请日：2006-10-16

Applicant: CORREX, INC. ,  BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, Alan ,  GAMMIE, James, S. ,  SMITH, Joseph, L., Jr.

Inventor： BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, Alan ,  GAMMIE, James, S. ,  SMITH, Joseph, L., Jr.

IPC: A61B17/11

CPC classification number: A61B17/32053 ,  A61B17/0218 ,  A61B2017/00252 ,  A61B2017/00349 ,  A61B2017/0038 ,  A61B2017/00557 ,  A61B2017/0237 ,  A61B2017/1107 ,  A61B2017/1135

Abstract: The invention relates to an apparatus and method for forming a hole in a wall of a hollow organ. The applicator includes a hole forming element for forming a hole in the wall of the organ, a positioning means (300) for positioning the hole forming element, and a retractor element (500). In addition, the applicator includes a sequencing means (600) for coordinating the relative movement of the retractor element and the hole forming element in a sequential manner to thereby carry out a procedure for forming a hole in the wall of the hollow organ. The sequencing means may further include a safety latch element operatively coupled to the retracting means and the hole forming element. The safety latch of the invention prevents damage to the internal surface of the organ during the formation of the hole.

Abstract translation: 本发明涉及一种在中空器官的壁上形成孔的装置和方法。 敷贴器包括用于在器官壁上形成孔的孔形成元件，用于定位孔形成元件的定位装置（300）和牵开元件（500）。 另外，涂抹器包括用于以顺序方式协调牵开器元件和孔形成元件的相对运动的排序装置（600），从而执行在中空器官的壁中形成孔的过程。 排序装置还可以包括可操作地联接到缩回装置和孔形成元件的安全闩锁元件。 本发明的安全闩锁在孔的形成期间防止器官内表面的损伤。

公开(公告)号：WO2005094525A2

公开(公告)日：2005-10-13

申请号：PCT/US2005/009844

申请日：2005-03-23

Applicant: CORREX, INC. ,  BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, A. ,  GAMMIE, James, S. ,  SMITH, Joseph, L., Jr.

Inventor： BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, A. ,  GAMMIE, James, S. ,  SMITH, Joseph, L., Jr.

IPC: A61B17/00 ,  A61B17/02 ,  A61B17/11 ,  A61B17/32 ,  A61F2/06

CPC classification number: A61B17/0218 ,  A61B17/11 ,  A61B17/320016 ,  A61B17/32053 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00557 ,  A61B2017/0237 ,  A61B2017/1107 ,  A61B2018/00392 ,  A61F2/064

Abstract: An apparatus and method for connecting a first conduit to the heart without the need for cardiopulmonary bypass. The first conduit may then be attached to a second conduit that has a prosthetic device interposed. The second conduit may then be connected to the aorta. The prosthetic device may be a prosthetic valve or a pump, for example. The apparatus of the present invention includes an implantable connector with first conduit component, a retractor expansion component, a coring component, and a pushing component. The retractor expansion component is slide-ably coupled to the coring component. The retractor expansion component serves to seat against and separate the inside apical wall of the left ventricle so that the coring component may cut cleanly through the myocardium to form a tissue plug without leaving any hanging attachments to the inside walls. By remaining seated against the inside wall, the retractor expansion component follows the tissue plug into the coring component. The surgeon applies force and rotary motion to the pushing component sufficient to cut the tissue plug and implant the prosthetic component.

Abstract translation: 一种用于将第一导管连接到心脏而不需要体外循环的装置和方法。 然后可以将第一导管连接到插入有假体装置的第二导管。 然后可以将第二导管连接到主动脉。 假体装置例​​如可以是人工瓣膜或泵。 本发明的装置包括具有第一管道部件的可植入连接器，牵开器膨胀部件，取芯部件和推动部件。 牵开器膨胀部件滑动地联接到取芯部件。 牵开器膨胀部件用于抵靠和分离左心室的顶端壁，使得取芯部件可以通过心肌切割干净地形成组织塞，而不会将悬挂的附件留在内壁上。 通过保持抵靠内壁的位置，牵开器膨胀部件沿着组织插塞进入取芯部件。 外科医生将力和旋转运动施加到推动部件足以切割组织塞并植入假体部件。

公开(公告)号：WO0248832A9

公开(公告)日：2002-12-27

申请号：PCT/US0147946

申请日：2001-12-13

Applicant: US POSTAL SERVICE ,  BROWN JOHN W

Inventor： BROWN JOHN W

IPC: B07C3/00 ,  G06F

CPC classification number: B07C3/00 ,  Y10S209/90

Abstract: A method and system for providing delivery point sequencing consistent with the invention includes assigning the plurality of items dynamic sequence numbers as the plurality of items pass through a sequencing component a first time, the sequencing component component comprising a plurality of partitions. Next the method and system include sorting the plurality of items into the plurality of partitions of the sequencing component as the plurality of items pass through the sequencing component the first time, each partition having a corresponding batch of items. And finally the method and system include sorting the items of each batch by the dynamic sequence numbers as the plurality of items pass through the sequencing component a second time, each of the plurality of partitions sorting only items of its corresponding batch.

Abstract translation: 用于提供符合本发明的递送点排序的方法和系统包括当多个项目第一次通过排序组件时分配多个项目动态序列号，排序组件组件包括多个分区。 接下来，该方法和系统包括当多个项目第一次通过排序组件时将多个项目排序到排序组件的多个分区中，每个分区具有对应的项目批次。 最后，该方法和系统包括当多个项目第二次通过排序组件时，通过动态序列号对每个批次的项目进行排序，多个分区中的每一个仅仅排序其相应批次的项目。

公开(公告)号：WO2014058511A3

公开(公告)日：2014-06-19

申请号：PCT/US2013051961

申请日：2013-07-25

Applicant: BYE UAS INC ,  BYE GEORGE ,  BICKEL MATT ,  BROWN JOHN W ,  MENDENHALL TODD ,  GOLDBERG BRIAN S ,  FRANZ RYAN W

Inventor： BYE GEORGE ,  BICKEL MATT ,  BROWN JOHN W ,  MENDENHALL TODD ,  GOLDBERG BRIAN S ,  FRANZ RYAN W

IPC: H04N7/18 ,  H04N7/015

CPC classification number: H04N5/2251 ,  B64C2201/127 ,  B64D47/08 ,  F16M11/10 ,  F16M11/18 ,  F16M11/2014 ,  H04N5/232 ,  H04N5/23241 ,  H04N5/23248 ,  H04N5/23258 ,  H04N5/2328

Abstract: A sensor system comprising specific subassemblies provides high definition video in small unmanned aerial systems. The sensor system provides for efficient space and power utilization.

Abstract translation: 包含特定子组件的传感器系统可在小型无人航空系统中提供高清视频。 传感器系统提供有效的空间和功率利用。

公开(公告)号：WO2014058511A9

公开(公告)日：2014-04-17

申请号：PCT/US2013/051961

申请日：2013-07-25

Applicant: BYE UAS, INC. ,  BYE, George ,  BICKEL, Matt ,  BROWN, John, W. ,  MENDENHALL, Todd ,  GOLDBERG, Brian, S. ,  FRANZ, Ryan, W.

Inventor： BYE, George ,  BICKEL, Matt ,  BROWN, John, W. ,  MENDENHALL, Todd ,  GOLDBERG, Brian, S. ,  FRANZ, Ryan, W.

IPC: H04N7/18 ,  H04N7/015

Abstract: A sensor system comprising specific subassemblies provides high definition video in small unmanned aerial systems. The sensor system provides for efficient space and power utilization.

公开(公告)号：WO2011003019A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/040818

申请日：2010-07-01

Applicant: CORREX, INC. ,  BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, Alan ,  GAMMIE, James, S. ,  LIEPERT, Anthony, G. ,  SMITH, Joseph, L., Jr.

Inventor： BEANE, Richard, M. ,  BROWN, John, W. ,  CRUNKLETON, James, Alan ,  GAMMIE, James, S. ,  LIEPERT, Anthony, G. ,  SMITH, Joseph, L., Jr.

IPC: A61F2/04

CPC classification number: A61F2/2418 ,  A61B17/11 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/06 ,  A61F2/064 ,  A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2002/061 ,  A61F2002/065 ,  A61M25/09 ,  A61M25/10 ,  A61M2025/1052

Abstract: A connector for joining a first hollow structure to the side wall of a second hollow structure, the connector comprising a fluid-constraining tube having a fluid-constraining neck extending therefrom, wherein the tube comprises a lumen having a first opening and a second opening and the neck comprises a lumen having a first opening and a second opening, the neck being joined to the tube so that the neck is in fluid communication with the tube intermediate the length of the tube, such that fluid enteπng the first opening of the tube can exit the second opening of the tube, and fluid entenng the first opening of the neck can exit the second opening of the tube at least the portions of the tube adjacent to the first opening of the tube and the second opening of the tube being biased radially outwardly so that they normally assume a radially-expanded configuration.

Abstract translation: 一种用于将第一中空结构连接到第二中空结构的侧壁的连接器，所述连接器包括具有从其延伸的流体约束颈部的流体约束管，其中所述管包括具有第一开口和第二开口的内腔， 颈部包括具有第一开口和第二开口的内腔，颈部连接到管，使得颈部与管的长度在管中流体连通，使得流入管的第一开口的流体可以 离开管的第二开口，并且颈部的第一开口的流体可以离开管的第二开口，至少管的与管的第一开口相邻的部分，并且管的第二开口径向偏压 使它们通常呈现径向扩张的构型。

公开(公告)号：WO2005094525A3

公开(公告)日：2009-04-02

申请号：PCT/US2005009844

申请日：2005-03-23

Applicant: CORREX INC ,  BEANE RICHARD M ,  BROWN JOHN W ,  CRUNKLETON JAMES A ,  GAMMIE JAMES S ,  SMITH JOSEPH L JR

Inventor： BEANE RICHARD M ,  BROWN JOHN W ,  CRUNKLETON JAMES A ,  GAMMIE JAMES S ,  SMITH JOSEPH L JR

IPC: A61B17/00 ,  A61B17/02 ,  A61B17/11 ,  A61B17/32 ,  A61F2/06

CPC classification number: A61B17/0218 ,  A61B17/11 ,  A61B17/320016 ,  A61B17/32053 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00557 ,  A61B2017/0237 ,  A61B2017/1107 ,  A61B2018/00392 ,  A61F2/064

Abstract: An apparatus and method for connecting a first conduit to the heart without the need for cardiopulmonary bypass. The first conduit may then be attached to a second conduit that has a prosthetic device interposed. The second conduit may then be connected to the aorta. The prosthetic device may be a prosthetic valve or a pump, for example. The apparatus of the present invention includes an implantable connector with first conduit component, a retractor expansion component, a coring component, and a pushing component. The retractor expansion component is slide-ably coupled to the coring component. The retractor expansion component serves to seat against and separate the inside apical wall of the left ventricle so that the coring component may cut cleanly through the myocardium to form a tissue plug without leaving any hanging attachments to the inside walls. By remaining seated against the inside wall, the retractor expansion component follows the tissue plug into the coring component. The surgeon applies force and rotary motion to the pushing component sufficient to cut the tissue plug and implant the prosthetic component.

Abstract translation: 一种用于将第一导管连接到心脏而不需要体外循环的装置和方法。 然后可以将第一导管连接到插入有假体装置的第二导管。 然后可以将第二导管连接到主动脉。 假体装置例​​如可以是人工瓣膜或泵。 本发明的装置包括具有第一管道部件的可植入连接器，牵开器膨胀部件，取芯部件和推动部件。 牵开器膨胀部件滑动地联接到取芯部件。 牵开器膨胀部件用于抵靠和分离左心室的顶端壁，使得取芯部件可以通过心肌切割干净地形成组织塞，而不会将悬挂的附件留在内壁上。 通过保持抵靠内壁的位置，牵开器膨胀部件沿着组织插塞进入取芯部件。 外科医生将力和旋转运动施加到推动部件足以切割组织塞并植入假体部件。

公开(公告)号：WO2007117612A1

公开(公告)日：2007-10-18

申请号：PCT/US2007/008600

申请日：2007-04-06

Applicant: CORREX, INC. ,  BEANE, Richard M. ,  BROWN, John W. ,  CRUNKLETON, James Alan ,  GAMMIE, James S. ,  SMITH, JR., Joseph L.

Inventor： BEANE, Richard M. ,  BROWN, John W. ,  CRUNKLETON, James Alan ,  GAMMIE, James S. ,  SMITH, JR., Joseph L.

IPC: A61F2/06 ,  A61B17/11

CPC classification number: A61B17/11 ,  A61B2017/00243 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/064

Abstract: The present invention relates to an apparatus and method for securing a connector conduit to a hollow organ. The method comprises forming a hole in a wall of the organ; inserting a connector conduit through the hole in the wall of the organ until a flange element comes into contact with the wall of the organ, the flange element being positioned on the connector conduit; and engaging a retention means with the wall of the organ to prevent movement of the connector conduit relative to the wall of the organ, the retention means being positioned on the connector conduit. Exemplary retaining means include a plurality of retaining pins positioned circumferentially around the connector conduit, a plurality of prongs positioned circumferentially around the connector conduit, a balloon positioned on the connector conduit, a torsion spring positioned on the connector conduit, a spiral spring positioned on the connector conduit, or combinations thereof.

Abstract translation: 本发明涉及一种用于将连接器管道固定到中空器官的装置和方法。 该方法包括在器官的壁上形成孔; 将连接器导管穿过器官壁的孔直到法兰元件与器官的壁接触，凸缘元件位于连接器导管上; 以及将保持装置与所述器官的壁接合以防止所述连接器导管相对于所述器官的壁移动，所述保持装置位于所述连接器导管上。 示例性保持装置包括围绕连接器导管周向定位的多个保持销，围绕连接器导管周向定位的多个插脚，定位在连接器导管上的气囊，位于连接器导管上的扭簧，位于 连接器导管或其组合。