公开(公告)号：WO2012135595A2

公开(公告)日：2012-10-04

申请号：PCT/US2012/031402

申请日：2012-03-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  MEITZ, David W., ,  THAKKAR, Birmal V., ,  BURNS, David M., ,  OLSON, David B., ,  PAVELKA, Lee A.,

Inventor： MEITZ, David W., ,  THAKKAR, Birmal V., ,  BURNS, David M., ,  OLSON, David B., ,  PAVELKA, Lee A.,

IPC: C08J5/18 ,  C08L23/08 ,  C08L33/04 ,  C08K5/3492 ,  C08F220/18

CPC classification number: G02B1/04 ,  C08F220/18 ,  C08K5/3492 ,  C08L23/0869 ,  G02B5/124 ,  G02B5/208 ,  C08L23/08

Abstract: The present application generally relates to EAA films including at least one triazine-based ultraviolet absorber. The present application also generally relates to retroreflective sheeting including an EAA film including a triazine-based ultraviolet absorber. One embodiments of the present application relates to a film, comprising poly(ethylene-co-acrylic acid) and a triazine-based UVA. Another embodiment of the present application relates to retroreflective sheeting, comprising: a plurality of cube corner elements; and a body layer adjacent to the cube corner elements, the body layer including poly(ethylene-co-acrylic acid) and a triazine-based UVA.

Abstract translation: 本申请通常涉及包括至少一种三嗪类紫外线吸收剂的EAA膜。 本申请还通常涉及包括包含三嗪基紫外线吸收剂的EAA膜的回射片材。 本申请的一个实施方案涉及包含聚（乙烯 - 共 - 丙烯酸）和基于三嗪的UVA的膜。 本申请的另一实施例涉及回射片材，其包括：多个立体角元件; 以及与立体角元件相邻的主体层，主体层包括聚（乙烯 - 共 - 丙烯酸）和三嗪基UVA。

公开(公告)号：WO2006053275A3

公开(公告)日：2007-08-16

申请号：PCT/US2005041114

申请日：2005-11-09

Applicant: COPERNIC TECHNOLOGIES INC ,  BURNS DAVID M

Inventor： BURNS DAVID M

IPC: G06F7/00 ,  G06F17/30

CPC classification number: G06Q30/02

Abstract: Described herein are methods and systems for choosing digital advertisements to send to a user's computer (10) while protecting private information. When a user performs a search using a public site (12) , the user's search information is stored in a database. The system builds a profile for the user based on the public search information, which can be used to select advertisements for delivery to a Web site accessed by the user. The system can also select advertisements based on information gleamed from a user's private (desktop) searches. For example, the system can use the content or category in which a user is searching to choose advertisements.

Abstract translation: 这里描述了用于选择数字广告以在保护私人信息的同时发送给用户的计算机（10）的方法和系统。 当用户使用公共站点（12）执行搜索时，用户的搜索信息被存储在数据库中。 该系统基于公共搜索信息为用户建立简档，该公共搜索信息可以用于选择用于传递给用户访问的网站的广告。 该系统还可以基于用户私人（桌面）搜索中闪烁的信息来选择广告。 例如，系统可以使用用户正在搜索的内容或类别来选择广告。

公开(公告)号：WO2006053275A2

公开(公告)日：2006-05-18

申请号：PCT/US2005/041114

申请日：2005-11-09

Applicant: COPERNIC TECHNOLOGIES, INC. ,  BURNS, David, M.

Inventor： BURNS, David, M.

IPC: G06F17/30

CPC classification number: G06Q30/02

Abstract: Described herein are methods and systems for choosing digital advertisements to send to a user's computer while protecting private information. When a user performs a search using a public site, the user's search information is stored in a database. The system builds a profile for the user based on the public search information, which can be used to select advertisements for delivery to a Web site accessed by the user. The system can also select advertisements based on information gleamed from a user's private (desktop) searches. For example, the system can use the content or category in which a user is searching to choose advertisements.

Abstract translation: 这里描述了用于选择数字广告以在保护私人信息的同时发送给用户计算机的方法和系统。 当用户使用公共站点执行搜索时，用户的搜索信息被存储在数据库中。 该系统基于公共搜索信息为用户建立简档，该公共搜索信息可以用于选择用于传递给用户访问的网站的广告。 该系统还可以基于用户私人（桌面）搜索中闪烁的信息来选择广告。 例如，系统可以使用用户正在搜索的内容或类别来选择广告。

公开(公告)号：WO2006044357A2

公开(公告)日：2006-04-27

申请号：PCT/US2005/036493

申请日：2005-10-12

Applicant: COPERNIC TECHNOLOGIES, INC. ,  BURNS, David, M. ,  WOODWARD, Mark, L.

Inventor： BURNS, David, M. ,  WOODWARD, Mark, L.

IPC: G06F17/30

CPC classification number: G06F17/30867

Abstract: Described herein are methods and systems for choosing digital advertisements to send to a user's computer while protecting private information. When a user performs a search using a public site, the user's search information is stored in a database. The system builds a profile for the user based on the public search information, which can be used to select advertisements for delivery to the user's computer. The system can also select advertisements based on information gleamed from a user's private (desktop) searches. For example, the system can use the category in which a user is searching to chose advertisements.

Abstract translation: 这里描述了用于选择数字广告以在保护私人信息的同时发送给用户计算机的方法和系统。 当用户使用公共站点执行搜索时，用户的搜索信息被存储在数据库中。 该系统基于公共搜索信息为用户建立一个配置文件，该公共搜索信息可用于选择用于递送给用户计算机的广告。 该系统还可以基于用户私人（桌面）搜索中闪烁的信息来选择广告。 例如，系统可以使用用户正在搜索的类别来选择广告。

公开(公告)号：WO2005117882A8

公开(公告)日：2006-04-20

申请号：PCT/US2005013434

申请日：2005-04-19

Applicant: INCYTE CORP ,  BURNS DAVID M ,  YAO WENQING ,  HE CHUNHONG

Inventor： BURNS DAVID M ,  YAO WENQING ,  HE CHUNHONG

IPC: A61K31/452 ,  A61K31/4545 ,  A61K31/4709 ,  A61K31/496 ,  C07D211/96 ,  C07D401/14 ,  C07D405/12 ,  C07D405/14

CPC classification number: C07D211/96 ,  C07D401/14 ,  C07D405/12 ,  C07D405/14

Abstract: The present invention provides compounds of Formula (I ) or (II), salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions.

Abstract translation: 本发明提供了式（I）或（II）的化合物，其盐形式或其前药，其中变量在本文中定义为金属蛋白酶如基质金属蛋白酶（MMP）和ADAMs的调节剂。 本文所述的化合物或组合物可用于治疗与金属蛋白酶活性相关的疾病，包括例如关节炎，癌症，心血管病症，皮肤病症，炎症或过敏性病症。

公开(公告)号：WO2012135595A3

公开(公告)日：2013-03-14

申请号：PCT/US2012031402

申请日：2012-03-30

Applicant: 3M INNOVATIVE PROPERTIES CO ,  MEITZ DAVID W ,  THAKKAR BIRMAL V ,  BURNS DAVID M ,  OLSON DAVID B ,  PAVELKA LEE A

Inventor： MEITZ DAVID W ,  THAKKAR BIRMAL V ,  BURNS DAVID M ,  OLSON DAVID B ,  PAVELKA LEE A

IPC: C08J5/18 ,  C08F220/18 ,  C08K5/3492 ,  C08L23/08 ,  C08L33/04

CPC classification number: G02B1/04 ,  C08F220/18 ,  C08K5/3492 ,  C08L23/0869 ,  G02B5/124 ,  G02B5/208 ,  C08L23/08

Abstract: The present application generally relates to EAA films including at least one triazine-based ultraviolet absorber. The present application also generally relates to retroreflective sheeting including an EAA film including a triazine-based ultraviolet absorber. One embodiments of the present application relates to a film, comprising poly(ethylene-co-acrylic acid) and a triazine-based UVA. Another embodiment of the present application relates to retroreflective sheeting, comprising: a plurality of cube corner elements; and a body layer adjacent to the cube corner elements, the body layer including poly(ethylene-co-acrylic acid) and a triazine-based UVA.

Abstract translation: 本申请一般涉及包括至少一种三嗪类紫外线吸收剂的EAA膜。 本申请一般也涉及包括三嗪系紫外线吸收剂的EAA膜的回射片材。 本申请的一个实施方案涉及包含聚（乙烯 - 共 - 丙烯酸）和三嗪基UVA的膜。 本申请的另一实施例涉及回射片材，其包括：多个立体角元件; 以及与立体角元件相邻的主体层，主体层包括聚（乙烯 - 共 - 丙烯酸）和三嗪基UVA。

公开(公告)号：WO2020051169A1

公开(公告)日：2020-03-12

申请号：PCT/US2019/049419

申请日：2019-09-04

Applicant: INCYTE CORPORATION ,  DOUTY, Brent ,  BURNS, David M. ,  COMBS, Andrew P. ,  JIA, Zhongjiang ,  LEVY, Daniel ,  YUE, Eddy W.

Inventor： DOUTY, Brent ,  BURNS, David M. ,  COMBS, Andrew P. ,  JIA, Zhongjiang ,  LEVY, Daniel ,  YUE, Eddy W.

IPC: C07D487/04 ,  C07D471/02 ,  C07D471/04 ,  A61K31/395 ,  A61K31/435 ,  A61K31/4353 ,  A61K31/437 ,  A61K31/495 ,  A61K31/4985

Abstract: The present invention relates to salts and crystalline forms of 2-(3-(8-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl)-4-methylphenyl)-3,3,3-trifluoro-2-hydroxypropanamide, crystalline forms of 8-amino-N-(2-hydroxy-2-methylpropyl)-3-(2-methyl-5-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide, and crystalline forms of 8-amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-d3)-5-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide, which are PI3K inhibitors useful in the treatment of cancer and other diseases.

公开(公告)号：WO2009042413A1

公开(公告)日：2009-04-02

申请号：PCT/US2008/075964

申请日：2008-09-11

Applicant: MOTOROLA, INC. ,  LUI, Alfred Ying Fai ,  BURNS, David M. ,  TAN, Alan

Inventor： LUI, Alfred Ying Fai ,  BURNS, David M. ,  TAN, Alan

IPC: G11B27/034 ,  G11B27/10 ,  G11B27/11 ,  G11B27/34 ,  G06F17/24 ,  G06F17/30 ,  H04M1/725

CPC classification number: G11B27/034 ,  G06F17/241 ,  G06F17/30017 ,  G06F17/3082 ,  G11B27/10 ,  G11B27/105 ,  G11B27/11 ,  G11B27/34

Abstract: The present invention discloses a textual annotation system for video recordings. Such a system can include a video recording, an annotation interface, and an annotation manager. The annotation interface can be configured to accept and execute a set of user-selectable commands for creating, modifying, and transmitting a user-created annotation set. The user-created annotation set can contains multiple textual annotations with associated placement data. The annotation manager can be configured to display the user-created annotation set synchronously with the video recording such that the contents of the video recording are unaltered.

Abstract translation: 本发明公开了一种用于视频记录的文本注释系统。 这样的系统可以包括视频记录，注释界面和注释管理器。 注释接口可以配置为接受和执行一组用户可选择的命令，用于创建，修改和传输用户创建的注释集。 用户创建的注释集可以包含多个具有关联展示位置数据的文本注释。 注释管理器可以被配置为与视频记录同步地显示用户创建的注释集，使得视频记录的内容不变。

公开(公告)号：WO2007084314A3

公开(公告)日：2008-03-27

申请号：PCT/US2007000695

申请日：2007-01-11

Applicant: INCYTE CORP ,  YAO WENQING ,  BURNS DAVID M ,  CHEN LIHUA ,  ZHUO JINCONG ,  HE CHUNHONG

Inventor： YAO WENQING ,  BURNS DAVID M ,  CHEN LIHUA ,  ZHUO JINCONG ,  HE CHUNHONG

IPC: C07D207/16 ,  A61K31/40 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/00 ,  A61P27/00 ,  C07D403/04

CPC classification number: C07D403/04 ,  C07D207/16 ,  C07D209/96 ,  C07D471/10 ,  C07D487/10

Abstract: The present invention relates to inhibitors of 11-ß hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-ß hydroxyl steroid dehydrogenase type 1 such as obesity and diabetes.

Abstract translation: 本发明涉及1型11-羟基类固醇脱氢酶抑制剂及其药物组合物。 本发明的化合物可用于治疗与11-β羟基类固醇脱氢酶1（例如肥胖症和糖尿病）的表达或活性相关的各种疾病。

公开(公告)号：WO2006044357A3

公开(公告)日：2007-10-11

申请号：PCT/US2005036493

申请日：2005-10-12

Applicant: COPERNIC TECHNOLOGIES INC ,  BURNS DAVID M ,  WOODWARD MARK L

Inventor： BURNS DAVID M ,  WOODWARD MARK L

IPC: G06F17/00 ,  G06F7/00 ,  G07G1/14

CPC classification number: G06F17/30867

Abstract: Described herein are methods and systems for choosing digital advertisements to send to a user's computer while protecting private information. When a user performs a search using a public site, the user's search information is stored in a database. The system builds a profile for the user based on the public search information, which can be used to select advertisements for delivery to the user's computer. The system can also select advertisements based on information gleamed from a user's private (desktop) searches. For example, the system can use the category in which a user is searching to chose advertisements.

Abstract translation: 这里描述了用于选择数字广告以在保护私人信息的同时发送给用户计算机的方法和系统。 当用户使用公共站点执行搜索时，用户的搜索信息被存储在数据库中。 该系统基于公共搜索信息为用户建立一个配置文件，该公共搜索信息可用于选择用于递送给用户计算机的广告。 该系统还可以基于用户私人（桌面）搜索中闪烁的信息来选择广告。 例如，系统可以使用用户正在搜索的类别来选择广告。