公开(公告)号：WO9842310A3

公开(公告)日：1998-12-23

申请号：PCT/EP9801831

申请日：1998-03-20

申请人： BOOTS CO PLC ,  JONES HUW LYN ,  BUTLER MALCOLM RICHARD

发明人： JONES HUW LYN ,  BUTLER MALCOLM RICHARD

IPC分类号： A61K9/20 ,  A61K31/192 ,  A61K9/00

CPC分类号： A61K9/2054 ,  A61K9/2009 ,  A61K9/2018 ,  A61K9/2059 ,  A61K31/192

摘要： A fast-release homogeneous compressed tablet composition comprising: (i) 1-50 % by weight flurbiprofen or a pharmaceutically acceptable salt thereof; and (ii) 50-99 % by weight compressible carrier material comprising a disintegrant and a compressible component selected from a sugar component, a starch component and an alkaline earth metal component; characterised in that the compressible carrier material further comprises microcrystalline cellulose present in a ratio to said compressible component of 1:4 to 4:1 parts by weight; and further characterised in that the crushing strength of the tablet is in the range 5-15 Kgf and that the disintegration time is less than 10 minutes.

摘要翻译： 一种快速释放均质压制片剂组合物，其包含：（i）1-50重量％的氟比洛芬或其药学上可接受的盐; 和（ii）50-99重量％的可压缩载体材料，其包含崩解剂和选自糖组分，淀粉组分和碱土金属组分的可压缩组分; 其特征在于所述可压缩载体材料还包含与所述可压缩组分的比例为1：4至4：1重量份的微晶纤维素; 其特征还在于片剂的抗碎强度在5-15Kgf范围内，崩解时间小于10分钟。

公开(公告)号：WO2008059219A1

公开(公告)日：2008-05-22

申请号：PCT/GB2007/004314

申请日：2007-11-13

申请人： THE UNIVERSITY OF SHEFFIELD ,  JONES, Richard, A., L. ,  RYAN, Anthony, J. ,  STOREY, Helen ,  BUTLER, Malcolm ,  CROOK, Colin, James

发明人： JONES, Richard, A., L. ,  RYAN, Anthony, J. ,  STOREY, Helen ,  BUTLER, Malcolm ,  CROOK, Colin, James

IPC分类号： B01D1/00 ,  C02F1/44

CPC分类号： C02F1/002 ,  B01D61/025 ,  B01D61/08 ,  B01D2311/2626 ,  B01D2313/24 ,  B01D2313/40 ,  C02F1/285 ,  C02F1/44 ,  C02F1/445

摘要： A water purification apparatus comprising a semi-permeable membrane capable of being contacted with a water source; a superabsorbent polymer capable of absorbing water across said semi-permeable membrane; a pressure application surface capable of transmitting pressure to the gel; and a permeable membrane through which absorbed water is capable of being released from the gel upon application of pressure thereto from said pressure application surface, wherein said permeable membrane is isolated in use from the water source by an isolation means

摘要翻译： 一种水净化装置，包括能够与水源接触的半透膜; 能够吸收横跨所述半透膜的水的超吸收性聚合物; 能够将压力传递到凝胶的压力施加表面; 以及可渗透膜，通过该渗透膜，从所述压力施加表面施加压力时，吸收的水能够从凝胶释放，其中所述渗透膜在使用中通过隔离装置与水源隔离