公开(公告)号：WO2007116365A2

公开(公告)日：2007-10-18

申请号：PCT/IB2007051257

申请日：2007-04-09

Applicant: ECOLE POLYTECH ,  DEPEURSINGE CHRISTIAN ,  CHARRIERE FLORIAN ,  COLOMB TRISTAN ,  MARIAN MIHAELA ANCA ,  MARQUET PIERRE

Inventor： DEPEURSINGE CHRISTIAN ,  CHARRIERE FLORIAN ,  COLOMB TRISTAN ,  MARIAN MIHAELA ANCA ,  MARQUET PIERRE

IPC: G01M11/02 ,  G03H1/08

CPC classification number: G03H1/0005 ,  G03H1/0406 ,  G03H1/041 ,  G03H1/08 ,  G03H1/16 ,  G03H2001/0033 ,  G03H2001/0445 ,  G03H2222/31 ,  G03H2223/17 ,  G03H2226/13

Abstract: The invention concerns a method and an apparatus for measuring and computing the Amplitude Point Spread Function (APSF). The invention may be advantageously used in the field of Digital Holographic Microscopy (DHM).

Abstract translation: 本发明涉及用于测量和计算幅度点扩展函数（APSF）的方法和装置。 本发明可有利地用于数字全息显微镜（DHM）领域。

公开(公告)号：WO2007116365A3

公开(公告)日：2007-10-18

申请号：PCT/IB2007/051257

申请日：2007-04-09

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) ,  DEPEURSINGE, Christian ,  CHARRIERE, Florian ,  COLOMB, Tristan ,  MARIAN, Mihaela, Anca ,  MARQUET, Pierre

Inventor： DEPEURSINGE, Christian ,  CHARRIERE, Florian ,  COLOMB, Tristan ,  MARIAN, Mihaela, Anca ,  MARQUET, Pierre

IPC: G03H1/00 ,  G01M11/02

Abstract: The invention concerns a method of and an apparatus for the measurement of the Amplitude Point Spread Function (APSF), of an Optical Imaging System (OIS), wherein the APSF is defined as the complex field distribution of the beam delivered by the OIS and originating from a point source. The apparatus comprising a) an illumination source; b) a point object, PO1 irradiated by said illumination source; c) an object beam coming from said point object, collected by the Optical imaging System and transmitted! to a Wavefront Sensing Device, WSD; and, d) a computer with processing means adapted to acquire the data from said WSD and adapted to compute the Amplitude Point Spread Function and derived parameters associated with the OIS. In a generic embodiment, the WSD is realized by means of a Mach-Zehnder interferometer providing a digital hologram to the processing means. The invention may be advantageously used in the field of Digital Holographic Microscopy (DHM).

公开(公告)号：WO2006090320A1

公开(公告)日：2006-08-31

申请号：PCT/IB2006/050532

申请日：2006-02-17

Applicant: LYNCEE TEC S.A. ,  COLOMB, Tristan ,  CUCHE, Etienne ,  ASPERT, Nicolas ,  KUEHN, Jonas ,  MARQUET, Pierre ,  DEPEURSINGE, Christian ,  MONTFORT, Frédéric ,  CHARRIERE, Florian ,  MARIAN, Anca ,  BOURQUIN, Sébastien ,  EMERY, Yves ,  HERMINJARD, Silvain

Inventor： COLOMB, Tristan ,  CUCHE, Etienne ,  ASPERT, Nicolas ,  KUEHN, Jonas ,  MARQUET, Pierre ,  DEPEURSINGE, Christian ,  MONTFORT, Frédéric ,  CHARRIERE, Florian ,  MARIAN, Anca ,  BOURQUIN, Sébastien ,  EMERY, Yves ,  HERMINJARD, Silvain

IPC: G06T5/20 ,  G06T5/00 ,  G01J9/00 ,  G01J9/02

CPC classification number: G01J9/02 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/0883 ,  G06T5/00

Abstract: A new way of mixing instrumental and digital means is described for the general field of wave front sensing. The present invention describes the use, the definition and the utility of digital operators, called digital wave front operators (DWFO) or digital lenses (DL) , specifically designed for the digital processing of wave fronts defined in amplitude and phase. DMFO are of particular interest for correcting undesired wave front deformations induced by instrumental defects or experimental errors . DWFO may be defined using a mathematical model, e.g. a polynomial function, which involves coefficients. The present invention describes automated and semi-automated procedures for calibrating or adjusting the values of these coefficients. These procedures are based on the fitting of mathematical models on reference data extracted from specific regions of a wave front called reference areas, which are characterized by the fact that specimen contributions are a priori known in reference areas.

Abstract translation: 对于波前传感的一般领域，描述了一种混合仪器和数字手段的新方法。 本发明描述了数字操作器，称为数字波前操作器（DWFO）或数字透镜（DL）的用途，定义和用途，专门用于在幅度和相位上定义的波前的数字处理。 DMFO对于校正由仪器缺陷或实验误差引起的不期望的波前变形是特别有意义的。 DWFO可以使用数学模型来定义，例如， 多项式函数，涉及系数。 本发明描述了用于校准或调整这些系数的值的自动和半自动程序。 这些程序基于对从称为参考区域的波前特定区域提取的参考数据的拟合，其特征在于样本贡献在参考区域中已知已知。