公开(公告)号：WO2012135693A2

公开(公告)日：2012-10-04

申请号：PCT/US2012/031566

申请日：2012-03-30

Applicant: EDWARDS LIFESCIENCES CORPORATION ,  ROWE, Stanton, J. ,  WU, Ming, H. ,  SCHNEIDER, Ralph ,  CORSO, Philip, P., Jr.

Inventor： ROWE, Stanton, J. ,  WU, Ming, H. ,  SCHNEIDER, Ralph ,  CORSO, Philip, P., Jr.

IPC: A61M39/06 ,  A61F2/24 ,  A61M25/088 ,  A61M25/10

CPC classification number: A61B17/0057 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/0293 ,  A61B17/3478 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00601 ,  A61B2017/00606 ,  A61B2017/00623 ,  A61B2017/00628 ,  A61B2017/00637 ,  A61B2017/00668 ,  A61B2017/00867 ,  A61B2017/00991 ,  A61B2017/0237 ,  A61B2017/3425

Abstract: A device, system, and method for providing access to, and sealing of, a body organ includes an implant device. An implant device has a main body having an internal access lumen, with a plurality of prongs extending from a distal end of the main body. The main body can include two lumens, one slidable within the other, to form a single continuous lumen with an adjustable length. The main body has an expanded configuration with an expanded diameter, and an unexpanded configuration with an unexpanded diameter. The prongs have a generally straight configuration where they extend distally of the distal end of the main body, and a bent configuration where the prongs bend around so that their tips extend proximally of the distal end of the main body. The device may include a hemostatic barrier to prevent fluid leakage therethrough when the main body is in the unexpanded configuration.

Abstract translation: 用于提供身体器官的接近和密封的装置，系统和方法包括植入装置。 植入装置具有主体，其具有内部进入腔，多个尖端从主体的远端延伸。 主体可以包括两个腔，一个可在另一个内滑动，以形成具有可调节长度的单个连续内腔。 主体具有扩展的直径扩张构型和未膨胀直径的未膨胀构造。 尖头具有大致直的构造，其中它们远离主体的远端延伸，并且弯曲构造，其中尖头弯曲，使得其尖端在主体的远端的近端延伸。 当主体处于未膨胀构型时，该装置可以包括止血屏障以防止流体从其中泄漏。

公开(公告)号：WO2012012761A8

公开(公告)日：2013-04-04

申请号：PCT/US2011045072

申请日：2011-07-22

Applicant: EDWARDS LIFESCIENCES CORP ,  OLSON CHRISTOPHER ,  RABITO GLEN T ,  ARMER DUSTIN P ,  MA MINH ,  MARR DEVIN ,  HUANG MARK ,  OKABE HIROSHI ,  STEWART KEVIN ,  CURTIS ALISON S ,  CORSO PHILIP P JR

Inventor： OLSON CHRISTOPHER ,  RABITO GLEN T ,  ARMER DUSTIN P ,  MA MINH ,  MARR DEVIN ,  HUANG MARK ,  OKABE HIROSHI ,  STEWART KEVIN ,  CURTIS ALISON S ,  CORSO PHILIP P JR

IPC: A61F2/24 ,  A61B17/00 ,  A61F2/82 ,  A61M25/088

CPC classification number: A61F2/243 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2250/006

Abstract: Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support structure and an expandable prosthetic valve are advanced through the aortic arch of a patient using a delivery system. The support structure is delivered to a position on or adjacent to the surface of the outflow side of the aortic valve (the support structure defining a support- structure interior). The expandable prosthetic valve is delivered into the aortic valve and into the support-structure interior. The expandable prosthetic heart valve is expanded while the expandable prosthetic heart valve is in the support-structure interior and while the support structure is at the position on or adjacent to the surface of the outflow side of the aortic valve, thereby causing one or more native leaflets of the aortic valve to be frictionally secured between the support structure and the expanded prosthetic heart valve.

Abstract translation: 这里公开了用于将假性心脏瓣膜递送到缺陷阀的方法，装置和系统的代表性实施例。 在一个实施例中，例如，支撑结构和可扩张的假体瓣膜通过使用递送系统的患者的主动脉弓前进。 支撑结构被输送到主动脉瓣（限定支撑结构内部的支撑结构）的流出侧的表面上或邻近的位置。 可膨胀假体瓣膜被输送到主动脉瓣并进入支撑结构内部。 可扩张假体心脏瓣膜膨胀，而可扩张假体心脏瓣膜处于支撑结构内部，而支撑结构处于主动脉瓣的流出侧表面上或邻近主动脉瓣的流出侧的位置，从而导致一个或多个本机 主动脉瓣的小叶被摩擦地固定在支撑结构和扩张的假体心脏瓣膜之间。

公开(公告)号：WO2012135693A3

公开(公告)日：2013-01-03

申请号：PCT/US2012031566

申请日：2012-03-30

Applicant: EDWARDS LIFESCIENCES CORP ,  ROWE STANTON J ,  WU MING H ,  SCHNEIDER RALPH ,  CORSO PHILIP P JR

Inventor： ROWE STANTON J ,  WU MING H ,  SCHNEIDER RALPH ,  CORSO PHILIP P JR

IPC: A61M39/06 ,  A61F2/24 ,  A61F2/958 ,  A61M25/088 ,  A61M25/10

CPC classification number: A61B17/0057 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/0293 ,  A61B17/3478 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00601 ,  A61B2017/00606 ,  A61B2017/00623 ,  A61B2017/00628 ,  A61B2017/00637 ,  A61B2017/00668 ,  A61B2017/00867 ,  A61B2017/00991 ,  A61B2017/0237 ,  A61B2017/3425

Abstract: A device, system, and method for providing access to, and sealing of, a body organ includes an implant device. An implant device has a main body having an internal access lumen, with a plurality of prongs extending from a distal end of the main body. The main body can include two lumens, one slidable within the other, to form a single continuous lumen with an adjustable length. The main body has an expanded configuration with an expanded diameter, and an unexpanded configuration with an unexpanded diameter. The prongs have a generally straight configuration where they extend distally of the distal end of the main body, and a bent configuration where the prongs bend around so that their tips extend proximally of the distal end of the main body. The device may include a hemostatic barrier to prevent fluid leakage therethrough when the main body is in the unexpanded configuration.

Abstract translation: 用于提供身体器官的接近和密封的装置，系统和方法包括植入装置。 植入装置具有主体，其具有内部进入腔，多个尖端从主体的远端延伸。 主体可以包括两个腔，一个可在另一个内滑动，以形成具有可调节长度的单个连续内腔。 主体具有扩展的直径扩张构型和未膨胀直径的未膨胀构造。 尖头具有大致直的构造，其中它们远离主体的远端延伸，并且弯曲构造，其中尖头弯曲，使得其尖端在主体的远端的近端延伸。 当主体处于未膨胀构型时，该装置可以包括止血屏障以防止流体从其中泄漏。