-
1.发明申请1,4-DISUBSTITUTED PIPERAZINES USEFUL IN THE THERAPY OF THE ASTHMA AND OF THE INFLAMMATION OF THE RESPIRATORY TRACT 审中-公开用于哮喘治疗和呼吸道感染炎症治疗的1,4 - 取消的哌嗪
公开(公告)号：WO1994007856A1
公开(公告)日：1994-04-14
申请号：PCT/EP1993002264
申请日：1993-08-24
Applicant: BOEHRINGER MANNHEIM ITALIA S.P.A. , LONG, Giorgio , SPINELLI, Silvano , ROZZI, Antonella , D'ALO', Simonetta , GALLICO, Licia
Inventor： BOEHRINGER MANNHEIM ITALIA S.P.A.
IPC: C07D207/08
CPC classification number: C07D401/12 , C07D403/12
Abstract: Compounds of general formula (I), wherein Ra, Rb, B and D have the meanings reported in the disclosure; processes for the preparation thereof. The compounds of the invention have antiasthmatic and antiinflammatory activities on the respiratory tract.
Abstract translation: 通式（I）的化合物，其中Ra，Rb，B和D具有本公开中报道的含义; 其制备方法。 本发明的化合物在呼吸道上具有止喘和抗炎活性。
-
2.发明申请[3H,7H]THIAZOLE[3,4-a]PYRIDINES HAVING ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT 审中-公开[3H，7H]噻唑[3,4-a]吡啶在呼吸道诱导下具有抗炎和抗炎活性
公开(公告)号：WO1993011133A1
公开(公告)日：1993-06-10
申请号：PCT/EP1992002783
申请日：1992-12-02
Applicant: BOEHRINGER MANNHEIM ITALIA S.p.A. , LONG, Giorgio , DE CILLIS, Giampiero , ROZZI, Antonella , D'ALO', Simonetta , GALLICO, Licia
Inventor： BOEHRINGER MANNHEIM ITALIA S.p.A.
IPC: C07D513/04
CPC classification number: C07D513/04
Abstract: Compounds of formula (I), having antiasthmatic and antiinflammatory actions on the respiratory tract, processes for the preparation thereof and pharmaceutical compositions containing them.
Abstract translation: 在呼吸道上具有抗哮喘和抗炎作用的式（I）化合物，其制备方法和含有它们的药物组合物。
-
3.发明申请2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT 审中-公开具有抗真菌和抗炎活性的2-氨基-4-亚氨基三唑在呼吸道感染
公开(公告)号：WO1993000342A1
公开(公告)日：1993-01-07
申请号：PCT/EP1992001377
申请日：1992-06-17
Applicant: BOEHRINGER MANNHEIM ITALIA S.P.A. , DE CILLIS, Gian, Piero , LONG, Giorgio , D'ALO', Simonetta , ROZZI, Antonella , GALLICO, Licia
Inventor： BOEHRINGER MANNHEIM ITALIA S.P.A.
IPC: C07D417/12
CPC classification number: C07D417/12 , C07D277/48
Abstract: 2-Amino-4-aryl-thiazole derivatives have interesting pharmacological properties, particularly antiasthmatic and anti-inflammatory activities on the respiratory tract and they can be used to prepare pharmaceutical compositions useful for the treatment of bronchial hyper-reactivity.
-
4.发明申请DERIVATIVES OF CARBOXY GEM-BISPHOSPHONATES WITH ANTITUMOR ACTIVITY, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开具有抗肿瘤活性的羧基GEM-二磷酸酯的衍生物，制备它们的方法和含有它们的药物组合物
公开(公告)号：WO1997049711A1
公开(公告)日：1997-12-31
申请号：PCT/EP1997003190
申请日：1997-06-12
Applicant: BOEHRINGER MANNHEIM ITALIA S.P.A. , LIVI, Valeria , D'ALO', Simonetta , SPINELLI, Silvano , CONTI, Marco
Inventor： BOEHRINGER MANNHEIM ITALIA S.P.A.
IPC: C07F09/38
CPC classification number: C07F9/4046 , C07F9/3869 , C07F9/564
Abstract: The present invention relates to conjugates of carboxy gem-bisphosphonic acids with alkylating agents. Such derivatives are endowed with remarkable antitumor activity and with specific activity on bone resorption. The present invention also relates to a process for preparing them and to pharmaceutical compositions containing them.
Abstract translation: 本发明涉及羧基双 - 二膦酸与烷基化剂的结合物。 这样的衍生物具有显着的抗肿瘤活性和对骨吸收的比活性。 本发明还涉及其制备方法和含有它们的药物组合物。
-
-
-
Search Results
4
records
(took 0.007 seconds)
