SYSTEM IMMUNE ACTIVATION METHOD USING NON CpG NUCLEIC ACIDS
    1.
    发明申请
    SYSTEM IMMUNE ACTIVATION METHOD USING NON CpG NUCLEIC ACIDS 审中-公开
    使用非CpG核酸的系统免疫激活方法

    公开(公告)号:WO2005079511A2

    公开(公告)日:2005-09-01

    申请号:PCT/US2005/005336

    申请日:2005-02-17

    IPC分类号: A61K9/127

    CPC分类号: A61K9/1272

    摘要: This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, or an infectious disease. Also disclosed are therapeutic compositions useful in such method.

    摘要翻译: 本发明涉及一种全身性免疫激活的方法,该方法在哺乳动物中有效引发系统性,非抗原特异性免疫应答和强抗原特异性免疫应答。 该方法对于保护哺乳动物免受包括癌症,与过敏性炎症相关的疾病或感染性疾病的疾病特别有效。 还公开了可用于这种方法的治疗组合物。

    COMPOSITIONS OF PATTERN RECOGNITION RECEPTOR-LIGAND: LIPID COMPLEXES AND METHODS OF USE THEREOF
    3.
    发明申请
    COMPOSITIONS OF PATTERN RECOGNITION RECEPTOR-LIGAND: LIPID COMPLEXES AND METHODS OF USE THEREOF 审中-公开
    模式识别受体 - 配体的组合物:脂质复合物及其使用方法

    公开(公告)号:WO2008057696A9

    公开(公告)日:2008-07-17

    申请号:PCT/US2007080850

    申请日:2007-10-09

    IPC分类号: A61K39/00

    摘要: This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, an infectious disease, or a condition associated with a deleterious activity of a self-antigen. Also disclosed are therapeutic compositions useful in such a method.

    摘要翻译: 本发明涉及在哺乳动物中有效引发系统性,非抗原特异性免疫应答和强抗原特异性免疫应答的疫苗和免疫激活方法。 该方法对于保护哺乳动物免受包括癌症,与变应性炎症相关的疾病,传染病或与自身抗原的有害活性相关的病症的疾病特别有效。 还公开了用于这种方法的治疗组合物。

    COMPOSITIONS OF PATTERN RECOGNITION RECEPTOR-LIGAND: LIPID COMPLEXES AND METHODS OF USE THEREOF
    8.
    发明申请
    COMPOSITIONS OF PATTERN RECOGNITION RECEPTOR-LIGAND: LIPID COMPLEXES AND METHODS OF USE THEREOF 审中-公开
    图案识别受体配体的组合物:脂质复合物及其使用方法

    公开(公告)号:WO2008057696A3

    公开(公告)日:2008-12-24

    申请号:PCT/US2007080850

    申请日:2007-10-09

    IPC分类号: A61K39/39

    摘要: This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, an infectious disease, or a condition associated with a deleterious activity of a self-antigen. Also disclosed are therapeutic compositions useful in such a method.

    摘要翻译: 本发明涉及疫苗和免疫激活方法,其有效地引发哺乳动物的全身性,非抗原特异性免疫应答和强抗原特异性免疫应答。 该方法对于保护哺乳动物免受包括癌症,与过敏性炎症相关的疾病,感染性疾病或与自身抗原的有害活性有关的病症的疾病特别有效。 还公开了可用于这种方法的治疗组合物。