公开(公告)号：WO1997000265A1

公开(公告)日：1997-01-03

申请号：PCT/US1996010327

申请日：1996-06-13

Applicant: DOWELANCO ,  DEAMICIS, Carl, Vincent ,  ANZEVENO, Peter, Biagio ,  MARTYNOW, Jacek, G. ,  MCLAREN, Kevin, L. ,  GREEN, Frederick, Richard, III ,  SPARKS, Thomas, C. ,  KIRST, Herbert, A. ,  CREEMER, Lawrence, Camillo ,  WORDEN, Thomas, V. ,  SCHOONOVER, Joe, Raymond, Jr. ,  GIFFORD, James, Michael ,  HATTON, Christopher, J. ,  HEGDE, Vidyadhar, B. ,  CROUSE, Gary, D. ,  THOREEN, Brian, R. ,  RICKS, Michael, J.

Inventor： DOWELANCO

IPC: C07H17/08

CPC classification number: C07H17/08 ,  A01N43/22 ,  A01N43/28 ,  A01N43/36 ,  A01N43/38 ,  A01N43/40 ,  A01N43/44 ,  A01N43/50 ,  A01N43/54 ,  A01N43/62 ,  A01N43/84 ,  A01N43/90 ,  A01N47/02 ,  A01N47/06 ,  A01N47/12 ,  A01N47/18 ,  A01N47/36 ,  A01N51/00 ,  A01N55/00 ,  A01N55/02 ,  A01N57/16 ,  A01N57/24 ,  A01N57/32 ,  C07D313/00

Abstract: The compounds of the present invention are prepared directly or indirectly by modifying the compounds that are naturally produced from Saccharopolyspora spinosa. The compounds of the invention have been shown to have activity against insects and mites. The compounds are prepared by modifying the rhamnose sugar, modification of the forosamine sugar, or starting with pseudoaglycone and then replacement with a nonsugar derivative or different sugar, modification of the 5, 6, 5-tricyclic and 12-membered macrocyclic lactone part of the compounds naturally produced or of the pseudoaglycone of the natural compounds.

Abstract translation: 本发明化合物直接或间接地通过修饰由多孢子孢多糖天然产生的化合物而制备。 已经证明本发明的化合物具有抗昆虫和螨的活性。 该化合物通过改变鼠李糖，修饰异山梨糖糖或从假曲马多开始制备，然后用非糖衍生物或不同的糖替代，修饰5,6-五环和12-元大环内酯部分 天然产生的化合物或天然化合物的假糖苷配基的化合物。