公开(公告)号：WO2003050261A3

公开(公告)日：2003-06-19

申请号：PCT/US2002/039478

申请日：2002-12-10

Applicant: BRISTOL-MYERS SQUIBB COMPANY ,  ATWAL, Karnail S, ,  GROVER, Gary J, ,  DING, Charles Z, ,  STEIN, Philip D, ,  LLOYD, John ,  AHMAD, Saleem ,  HAMANN, Lawrence G, ,  GREEN, David ,  FERRARA, Francis N,

Inventor： ATWAL, Karnail S, ,  GROVER, Gary J, ,  DING, Charles Z, ,  STEIN, Philip D, ,  LLOYD, John ,  AHMAD, Saleem ,  HAMANN, Lawrence G, ,  GREEN, David ,  FERRARA, Francis N,

IPC: A61P9/00

Abstract: Compounds having formula (I), and pharmaceutically acceptable salts thereof, are useful for modulating mitochondrial F 1 F 0 ATPase activity and treating ischemic conditions including myocardial infarction, congestive heart failure, and cardiac arrhythmias.

公开(公告)号：WO03050261A2

公开(公告)日：2003-06-19

申请号：PCT/US0239478

申请日：2002-12-10

Applicant: SQUIBB BRISTOL MYERS CO ,  ATWAL KARNAIL S ,  GROVER GARY J ,  DING CHARLES Z ,  STEIN PHILIP D ,  LLOYD JOHN ,  AHMAD SALEEM ,  HAMANN LAWRENCE G ,  GREEN DAVID ,  FERRARA FRANCIS N

Inventor： ATWAL KARNAIL S ,  GROVER GARY J ,  DING CHARLES Z ,  STEIN PHILIP D ,  LLOYD JOHN ,  AHMAD SALEEM ,  HAMANN LAWRENCE G ,  GREEN DAVID ,  FERRARA FRANCIS N

IPC: A61P9/00 ,  C07D231/12 ,  C07D233/54 ,  C07D235/06 ,  C07D235/10 ,  C07D235/14 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D521/00 ,  C12N

CPC classification number: C07D233/54 ,  C07D231/12 ,  C07D233/56 ,  C07D235/06 ,  C07D235/14 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12

Abstract: Compounds having formula (I), and pharmaceutically acceptable salts thereof, are useful for modulating mitochondrial F>10

Abstract translation: 具有式（I）的化合物及其药学上可接受的盐可用于调节线粒体F> 10