公开(公告)号：WO2004071529A2

公开(公告)日：2004-08-26

申请号：PCT/IB2004/000366

申请日：2004-02-03

Applicant: PFIZER PRODUCTS INC. ,  COHEN, Bruce, David ,  BEDIAN, Vahe ,  WANG, Huifen, Faye ,  OBROCEA, Mihail ,  GOMEZ-NAVARRO, Jesus ,  CUSMANO, John, Daniel ,  GUYOT, Deborah, Jean ,  PAGE, Kelly, Lynn

Inventor： COHEN, Bruce, David ,  BEDIAN, Vahe ,  WANG, Huifen, Faye ,  OBROCEA, Mihail ,  GOMEZ-NAVARRO, Jesus ,  CUSMANO, John, Daniel ,  GUYOT, Deborah, Jean ,  PAGE, Kelly, Lynn

IPC: A61K39/395

CPC classification number: C07K16/2863 ,  A61K39/39541 ,  A61K2039/505 ,  C07K16/2896 ,  C07K2317/21 ,  C07K2317/56 ,  Y02P20/582 ,  A61K2300/00

Abstract: The present invention relates to a therapeutic method comprising administering anti­IGF-IR antibodies, particularly human anti-IGF-IR antibodies to a subject for the treatment of certain disorders preferably in conjunction with administration of another therapeutic agent. The invention further relates to pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment.

Abstract translation: 本发明涉及一种治疗方法，其包括对受试者施用抗-IGF-IR抗体，特别是人抗IGF-1R抗体，用于治疗某些病症，优选与其它治疗剂的施用相结合。 本发明还涉及包含这些抗体的药物组合物和使用抗体及其组合物进行治疗的方法。

公开(公告)号：WO2004071529A3

公开(公告)日：2005-05-06

申请号：PCT/IB2004000366

申请日：2004-02-03

Applicant: PFIZER PROD INC ,  COHEN BRUCE DAVID ,  BEDIAN VAHE ,  WANG HUIFEN FAYE ,  OBROCEA MIHAIL ,  GOMEZ-NAVARRO JESUS ,  CUSMANO JOHN DANIEL ,  GUYOT DEBORAH JEAN ,  PAGE KELLY LYNN

Inventor： COHEN BRUCE DAVID ,  BEDIAN VAHE ,  WANG HUIFEN FAYE ,  OBROCEA MIHAIL ,  GOMEZ-NAVARRO JESUS ,  CUSMANO JOHN DANIEL ,  GUYOT DEBORAH JEAN ,  PAGE KELLY LYNN

IPC: A61K39/395 ,  A61P5/00 ,  A61P9/10 ,  A61P25/28 ,  A61P35/00 ,  A61P37/00 ,  C07K16/28

CPC classification number: C07K16/2863 ,  A61K39/39541 ,  A61K2039/505 ,  C07K16/2896 ,  C07K2317/21 ,  C07K2317/56 ,  Y02P20/582 ,  A61K2300/00

Abstract: The present invention relates to a therapeutic method comprising administering anti­IGF-IR antibodies, particularly human anti-IGF-IR antibodies to a subject for the treatment of certain disorders preferably in conjunction with administration of another therapeutic agent. The invention further relates to pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment.

Abstract translation: 本发明涉及一种治疗方法，其包括对受试者施用抗-IGF-IR抗体，特别是人抗IGF-1R抗体，用于治疗某些病症，优选与其它治疗剂的施用相结合。 本发明还涉及包含这些抗体的药物组合物和使用抗体及其组合物进行治疗的方法。