公开(公告)号：WO2005112964A1

公开(公告)日：2005-12-01

申请号：PCT/US2005/017541

申请日：2005-05-19

Applicant: NATURAL SOURCE INTERNATIONAL ,  HALL, John, C. ,  BELJANSKI, Sylvie

Inventor： HALL, John, C. ,  BELJANSKI, Sylvie

IPC: A61K35/78

CPC classification number: A61K36/24 ,  A61K31/475 ,  A61K2300/00

Abstract: A method and composition for preventing prostate cancer and/or reducing PSA levels and/or alleviating the symptoms of BPH (Benign Prostatic Hyperplasia) or PIN (prostatic intraepithelial neoplasia) by administration of an effective amount of a mixture of flavopereirine and alstonine. A method and composition for treating low-grade prostate cancer and preventing the onset of metastatic disease and/or reducing the doubling time of PSA levels in men with positive biopsies showing relatively low Gleason scores and morphologies characteristic of non-invasive, slow-progressing prostate cancer. The flavopereirine and alstonine can be in the form of natural extracts derived from Pao Pereira and Rauwolfia Vomitoria , respectively. Alternatively, these two active compounds can be administered in purified form. The composition can be in included in a kit along with instructions for use in a treatment regimen.

Abstract translation: 通过施用有效量的黄曲霉素和阿尔斯汀的混合物，预防前列腺癌和/或降低PSA水平和/或减轻BPH（良性前列腺增生症）或PIN（前列腺上皮内瘤变）的症状的方法和组合物。 用于治疗低级前列腺癌并预防转移性疾病发作和/或减少具有阳性活组织检查的男性PSA水平倍增时间的方法和组合物显示出相对较低的格列森评分和非侵入性，缓慢进展的前列腺特征的形态 癌症。 黄曲霉素和阿司匹林可以分别是由派佩雷拉（Pao Pereira）和萝维（Rauwolfia Vomitoria）衍生的天然提取物。 或者，这两种活性化合物可以以纯化形式施用。 组合物可以包含在试剂盒中以及用于治疗方案的说明书中。

公开(公告)号：WO2007076156A3

公开(公告)日：2007-09-07

申请号：PCT/US2006049401

申请日：2006-12-26

Applicant: WEBB WHEEL RPODUCTS INC ,  LEVERING PAUL D ,  ZILLS JEREMY L ,  CORNETT BYRON E ,  YANT TIMOTHY M ,  HALL JOHN C

Inventor： LEVERING PAUL D ,  ZILLS JEREMY L ,  CORNETT BYRON E ,  YANT TIMOTHY M ,  HALL JOHN C

IPC: F16D65/827

CPC classification number: F16D65/827 ,  F16D65/10

Abstract: One embodiment of a brake drum includes a cylindrical main body portion (12), a brake drum mounting flange portion (18), a brake drum transition portion (24), the brake drum transition portion extending between the cylindrical main body portion and the mounting flange portion, the transition portion having a plurality of vent openings (28), and one air scoop secured (34) at each of the vent openings, whereby rotation of the brake drum and air scoop induces air movement within a brake drum cavity defined by the main body portion. Each air scoop defines a louver opening (62) which faces the angular direction of drum rotation, an air channel in fluid communication with the louver opening and the brake drum cavity, and a deflection surface (64) located in the air channel. The deflection surface is positioned to re-direct air movement entering the louver opening at an angular direction, to a generally radial and inboard direction.

Abstract translation: 制动鼓的一个实施例包括圆柱形主体部分（12），制动鼓安装凸缘部分（18），制动鼓过渡部分（24），制动鼓过渡部分在圆柱形主体部分和安装件 凸缘部分，过渡部分具有多个通气口（28），以及一个空气勺在每个通气口处固定（34），由此制动鼓和空气勺的旋转引起在由 主体部分。 每个空气勺具有面向滚筒旋转方向的百叶窗开口（62），与百叶窗开口和制动鼓空腔流体连通的空气通道以及位于空气通道中的偏转表面（64）。 偏转表面被定位成重新引导进入窗板开口的空气移动在一个角度方向上，大致径向和内侧方向。

公开(公告)号：WO2007076156A8

公开(公告)日：2008-11-06

申请号：PCT/US2006049401

申请日：2006-12-26

Applicant: WEBB WHEEL PRODUCTS INC ,  ZILLS JEREMY L ,  CORNETT BYRON E ,  LEVERING PAUL D ,  YANT TIMOTHY M ,  HALL JOHN C

Inventor： ZILLS JEREMY L ,  CORNETT BYRON E ,  LEVERING PAUL D ,  YANT TIMOTHY M ,  HALL JOHN C

IPC: F16D65/827

CPC classification number: F16D65/827 ,  F16D65/10

Abstract: One embodiment of a brake drum includes a cylindrical main body portion (12), a brake drum mounting flange portion (18), a brake drum transition portion (24), the brake drum transition portion extending between the cylindrical main body portion and the mounting flange portion, the transition portion having a plurality of vent openings (28), and one air scoop secured (34) at each of the vent openings, whereby rotation of the brake drum and air scoop induces air movement within a brake drum cavity defined by the main body portion. Each air scoop defines a louver opening (62) which faces the angular direction of drum rotation, an air channel in fluid communication with the louver opening and the brake drum cavity, and a deflection surface (64) located in the air channel. The deflection surface is positioned to re-direct air movement entering the louver opening at an angular direction, to a generally radial and inboard direction.

Abstract translation: 制动鼓的一个实施例包括圆柱形主体部分（12），制动鼓安装凸缘部分（18），制动鼓过渡部分（24），制动鼓过渡部分在圆柱形主体部分和安装件 凸缘部分，过渡部分具有多个通气开口（28），以及一个空气勺在每个通气口处固定（34），由此制动鼓和空气勺的旋转引起在由 主体部分。 每个空气勺具有面向滚筒旋转角度方向的百叶窗开口（62），与百叶窗开口和制动鼓空腔流体连通的空气通道以及位于空气通道中的偏转表面（64）。 偏转表面被定位成将空气移动重新引导到沿着方向的大致径向和内侧的方向进入百叶窗开口。

公开(公告)号：WO2007076156A2

公开(公告)日：2007-07-05

申请号：PCT/US2006/049401

申请日：2006-12-26

Applicant: WEBB WHEEL RPODUCTS INC. ,  LEVERING, Paul, D. ,  ZILLS, Jeremy, L. ,  CORNETT, Byron, E. ,  YANT, Timothy, M. ,  HALL, John, C.

Inventor： LEVERING, Paul, D. ,  ZILLS, Jeremy, L. ,  CORNETT, Byron, E. ,  YANT, Timothy, M. ,  HALL, John, C.

IPC: F16D65/827

CPC classification number: F16D65/827 ,  F16D65/10

Abstract: One embodiment of a brake drum includes a cylindrical main body portion, a brake drum mounting flange portion, a brake drum transition portion, the brake drum transition portion extending between the cylindrical main body portion and the mounting flange portion, the transition portion having a plurality of vent openings, and one air scoop secured at each of the vent openings, whereby rotation of the brake drum and air scoop induces air movement within a brake drum cavity defined by the main body portion. Each air scoop defines a louver opening which faces the angular direction of drum rotation, an air channel in fluid communication with the louver opening and the brake drum cavity, and a deflection surface located in the air channel. The deflection surface is positioned to re-direct air movement entering the louver opening at an angular direction, to a generally radial and inboard direction

Abstract translation: 制动鼓的一个实施例包括圆柱形主体部分，制动鼓安装凸缘部分，制动鼓过渡部分，在圆柱形主体部分和安装凸缘部分之间延伸的制动鼓过渡部分，过渡部分具有多个 的通风口，以及一个固定在每个通风口处的气铲，由此制动鼓和空气勺的旋转引起在由主体部分限定的制动鼓腔内的空气运动。 每个空气勺具有面向滚筒旋转角度方向的百叶窗开口，与百叶窗开口和制动鼓空腔流体连通的空气通道以及位于空气通道中的偏转表面。 偏转表面被定位成将空气流动沿着角度方向重新引导到大致径向和内侧方向

公开(公告)号：WO2007019200A1

公开(公告)日：2007-02-15

申请号：PCT/US2006/030172

申请日：2006-08-03

Applicant: WEBB WHEEL PRODUCTS, INC. ,  LEVERING, Paul, D. ,  ZILLS, Jeremy, L. ,  HALL, John, C.

Inventor： LEVERING, Paul, D. ,  ZILLS, Jeremy, L. ,  HALL, John, C.

IPC: F16D65/10

CPC classification number: B21D53/34 ,  F16D65/10 ,  F16D2065/132 ,  F16D2069/0458 ,  F16D2069/0491 ,  F16D2200/0013 ,  Y10T29/49988

Abstract: A vehicle composite brake drum (10) is provided and includes a brake drum shell (12), and a brake drum liner (22), the brake drum liner (22) is formed of compacted graphite iron. A method of manufacturing the vehicle composite brake drum includes forming a brake drum shell and then forming a brake drum liner of compacted graphite iron.

Abstract translation: 提供了一种车辆复合制动鼓（10），其包括制动鼓壳（12）和制动鼓衬套（22），所述制动鼓衬套（22）由压实的石墨铁制成。 一种制造车辆用复合制动鼓的方法包括：制作制动鼓壳，然后形成压实石墨铁的制动鼓衬套。