CATALYST AND A PROCESS FOR PREPARATION OF ALDEHYDES IN THE PRESENCE OF SAID CATALYST
    4.
    发明申请
    CATALYST AND A PROCESS FOR PREPARATION OF ALDEHYDES IN THE PRESENCE OF SAID CATALYST 审中-公开
    催化剂和方法,该催化剂的存在下生产醛

    公开(公告)号:WO1997049490A1

    公开(公告)日:1997-12-31

    申请号:PCT/EP1997003169

    申请日:1997-06-18

    IPC分类号: B01J31/16

    摘要: The invention relates to a catalyst containing rhodium and a compound of the general formula (I), in which R , R and R are identical or different and independently of each other are hydrogen, an alkyl group or alkoxy group with 1 to 4 carbon atoms, an alkenyl group with 2 to 4 carbon atoms, or R and R including the carbon atoms connected therewith in each case form a ring with 6 carbon atoms, m and n independently of each other are 0 or 1, and (m+n) is equal to 1 or 2, and R is an unsubstituted phenyl radical or naphthyl radical or a phenyl radical or naphthyl radical substituted by an alkyl group with 1 to 4 carbon atoms, an amino group or dialkyl amino group with a total of 2 to 8 carbon atoms. The invention also relates to a process for preparation of aldehydes by reaction of an olefinic compound having 2 to 20 carbon atoms with carbon monoxide and hydrogen in the presence of said catalyst.

    摘要翻译: 本发明涉及一种催化剂,其包含铑和通式(I)的化合物,其中R <1>,R <2>和R <3>是相同的或不同的,并且各自独立地是氢,烷基或具有1烷氧基 站立或4个碳原子,碳原子数2〜4的链烯基,R <1>和R <2>,包括分别连接的碳原子形成具有6个碳原子,m和环n独立地为0或1,(M + N )等于1或2,并且R是未取代的或由具有1至4个碳原子,氨基或取代的苯基或萘基二烷基氨基的碳原子数2〜8的烷基。 本发明还涉及一种用于通过具有一氧化碳和氢气在该催化剂的存在2至20个碳原子的烯属化合物进行反应制备醛的方法。

    RING-FUSED DIHYDROPYRANES, PROCESS FOR THE PREPARATION AND USE THEREOF
    5.
    发明申请
    RING-FUSED DIHYDROPYRANES, PROCESS FOR THE PREPARATION AND USE THEREOF 审中-公开
    RING ANNE内衬二氢吡喃,方法生产及其用途

    公开(公告)号:WO1997048691A1

    公开(公告)日:1997-12-24

    申请号:PCT/EP1997003146

    申请日:1997-06-18

    IPC分类号: C07D311/74

    CPC分类号: C07D311/04

    摘要: The invention relates to compounds of the formula (I), in which the radicals R , R , R and A have the meaning given in the description. The invention also relates to a process for the preparation of the compounds of the formula (I) by solid phase synthesis, and use of said compounds as drugs.

    摘要翻译: 本发明涉及式(I)的化合物,其中基团R <1>,R <2>,R <3>和A具有在说明书中所列出的含义。 本发明还涉及用于制备式(I)通过固相合成,所述化合物和它们作为药物的用途。

    ANTIFUNGAL PEPTIDES FROM SCLERODERMA TEXENSE
    9.
    发明申请
    ANTIFUNGAL PEPTIDES FROM SCLERODERMA TEXENSE 审中-公开
    抗真菌肽硬皮病texense

    公开(公告)号:WO1997036921A1

    公开(公告)日:1997-10-09

    申请号:PCT/EP1997001507

    申请日:1997-03-25

    IPC分类号: C07K07/02

    CPC分类号: C07K7/02 A61K38/00

    摘要: The invention relates to novel peptides, i.e. texenomycines, from Scleroderma texense, a process for their production and their use as medicaments, especially as antimycotics. The texenomycines of this invention are distinguished in particular by the amino acid sequence (I) FS-Pro-Aib-Aib-Aib-Aib-Ala-Ala-Aib-ssAla-Leu-Aib-ssAla-Ala-Aib-ssAla-Ala-Aib-Aib-Aib-Ala-Arg-ol, in which FS is an ox-fatty acid radical, Aib is aminoisobutyric acid and Arg-ol is argininol.

    摘要翻译: 本发明涉及新的肽,即texenomycins,硬皮病的texense,它们的制备以及它们作为药物作为抗真菌剂的用途,特别是过程。 (I)FS-PRO-AIB-AIB-AIB-AIB酰-Ala-Ala-AIB-β丙氨酸 - 亮氨酸-AIB-β丙氨酸 - 丙氨酸 - 丙氨酸的βAib-根据本发明所述的texenomycins是特别杰出的由氨基酸序列 的ala-AIB-AIB-AIB-丙氨酸 - 精氨酸醇的方法,其中FS表示桥的脂肪酸基团,Aib取代氨基异丁酸和Arg醇=精氨。

    PROCESS FOR PREPARING HETEROCYCLIC CARBENES
    10.
    发明申请
    PROCESS FOR PREPARING HETEROCYCLIC CARBENES 审中-公开
    用于生产杂环卡宾

    公开(公告)号:WO1997034875A1

    公开(公告)日:1997-09-25

    申请号:PCT/EP1997001296

    申请日:1997-03-14

    IPC分类号: C07D233/10

    摘要: The invention concerns a process for preparing heterocyclic carbenes of general formula (I) in which R1, R2, R3 and R4 are identical or different and mean saturated or unsaturated, straight-chain, branched or cyclic, unsubstituted or substituted Ci-Ci alkyl, C2-C5 alkylidene, C2-C5 alkylidine, C7-C19 aralkyl or C6-C14 alkyl groups, R3 and R4 can also stand for hydrogen or form jointly anellated, substituted or unsubstituted groups with between 3 and 7 carbon atoms and X stands for carbon or nitrogen, R3 being dropped if X is nitrogen. The process is carried out by reacting azolium salts with a deprotonizing reagent in pure liquid ammonia or in pure organic amine or a mixture of liquid ammonia or an organic amine and an organic polar-aprotic solvent. This process enables a plurality of in particular temperature-sensitive carbenes to be produced under mild reaction conditions at temperatures of between -75 and 0°C.