Abstract:
Provided herein are tuberculatin analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.
Abstract:
An assembly to inactivate microbes in air flowing there through comprising an indirect air flow pathway, wherein the indirect air flow pathway comprises micro structures, micro cilia or meshes; wherein in the indirect air flow pathway a plurality microbial deactivation apparatuses are disposed. The plurality microbial deactivation apparatuses comprise at least one UV radiation apparatus (130), at least one physical nanometal oxide or nanometal apparatus (140), at least one negative ion apparatus (120), at least one temperature raising apparatus, at least one chemical oxidizer apparatus (150) and at least one organic antimicrobial apparatus (160). The assembly is effective in deactivation and removal of airborne particles, microbes, nanoparticles, gaseous and toxins.
Abstract:
Provided is a platform technology to deliver RNA therapeutics into cells. It provides a system for delivery of RNA molecules for biomedical purposes. The modular protein-based system described allows for customization of protein modules to achieve specificity in cell-targeting, thus having the ability to be optimized for treating different diseases. Examples of types of diseases that could adopt this technology for treatment include cancer, neurodegenerative diseases and viral infection.
Abstract:
The present invention relates to a group of derivatives synthesized based on the ent -kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. In particular, the chemical entities of such synthetic diterpene compounds in the manufacture of a medicament is for the treatment of tumors or cancers.
Abstract:
The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional-PDT and imaging-gadolinium complex (Gd-N) with a molecular formula(I), which can target cancer, cells specifically. The present invention provides a PDT drug that can specifically localize on the anionic cell membrane of cancer cells in which its laser-excited photoemission signal can be monitored without triggering the phototoxic generation of reactive oxygen species-singlet oxygen-prior to due excitation. The present invention also provides the use of Gd-N as a tumor selective PDT photosensitizer modality.
Abstract:
A method of gait measurement using tri-axial accelerometer/gyro in mobile devices for monitoring and improving the physical movement of a moving subject, comprising: using a tri-axial accelerometer to formulate: a signature based on measurements of walking, heaving and lateral movements of said subject; and a quantitative indicator indicating the power level dispensed by said subject to keep balance during motion.
Abstract:
Patentiflorin A analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.
Abstract:
This invention is about a novel image registration. This rigid registration is based on multiple surfaces arranged in a 3D relationship in the Cartesian coordinate system through a fiducial marker. In comparison to surface-based registration, this registration process provides more accurate registration or requires a smaller fiducial marker for the same level of registration accuracy. Moreover, this fiducial marker enables measuring coordinates in the physical domain; therefore the registration error can be measured by comparing coordinates of specific points in both physical and virtual domains. This has a potential application in comparing the imaging physical-to-image (PI) or printing image-to-physical (IP) modalities, for example, to compare the accuracies of the 3D model created by computed tomography and optical scanners. Other potential application also includes assisting a surgical navigation in a dental implant placement. The proposed fiducial marker therefore has potential development in the application of virtual reality.
Abstract:
New anticancer and anti-obesity agents based on the cyclic peptide compounds are disclosed, and its preparation and application method for treating cancer and obesity diseases are also disclosed.
Abstract:
Method and apparatus of an eye gaze tracking system, using a generic camera under normal environment,detecting a user's iris and eye corner position associated with at least one eye iris center and at least one eye corner of the user to determine an eye vector associated with the user's gaze direction, processing the eye vector for application of a head pose estimation model arranged to model a head pose of the user so as to devise one or more final gaze points of the user. The system features low cost, simple operation and tolerates large illumination changes.