公开(公告)号：WO2009131423A3

公开(公告)日：2009-12-23

申请号：PCT/KR2009002173

申请日：2009-04-24

Applicant: UNIV KYUNG HEE UNIV IND COOP GROUP ,  MEDIKAN INC ,  CHUNG IN SIK ,  KIM KYUNG IL ,  LEE JONG MIN ,  LEE HYUN HO ,  SHON DONG HWA ,  KIM WON YONG ,  LEE HEEYOUNG ,  CHUNG HO YONG ,  CHUNG HA YOUNG ,  HWANG BO JEON ,  YOO KI HYUN ,  KIM JONG BUM

Inventor： CHUNG IN SIK ,  KIM KYUNG IL ,  LEE JONG MIN ,  LEE HYUN HO ,  SHON DONG HWA ,  KIM WON YONG ,  LEE HEEYOUNG ,  CHUNG HO YONG ,  CHUNG HA YOUNG ,  HWANG BO JEON ,  YOO KI HYUN

IPC: C12N15/33 ,  C12N15/63

CPC classification number: C12N15/8258

Abstract: The present invention relates to a novel hepatitis A virus antigen gene and transformed plants with the gene, more particularly to a novel hepatitis A virus antigen gene synthesized by optimization of a genetic code, a recombinant vector containing the gene and plants transformed with the recombinant vector. According to the invention, the use of a synthesized antigen gene of hepatitis A virus makes it possible to prepare recombinant hepatitis A virus vaccine materials at a high efficiency, and transformed plants expressing a hepatitis A virus antigen are useful as functional food materials and orally administrated vaccine materials.

Abstract translation: 本发明涉及一种新型甲型肝炎病毒抗原基因和具有该基因的转化植物，更具体地涉及通过优化遗传密码合成的新型甲型肝炎病毒抗原基因，含有该基因的重组载体和用该重组载体转化的植物 。 根据本发明，甲型肝炎病毒合成抗原基因的使用使得能够以高效率制备重组甲型肝炎病毒疫苗材料，表达甲型肝炎病毒抗原的转化植物可用作功能性食品材料并经口服 疫苗材料。