专利检索 ap:"JL, Wenzhi" 第 1 页

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发明申请
COVALENT INHIBITORS OF CREATINE KINASE (CK) AND USES THEREOF FOR TREATING AND PREVENTING CANCER 审中-公开

公开(公告)号：WO2022087433A1

公开(公告)日：2022-04-28

申请号：PCT/US2021/056280

申请日：2021-10-22

申请人： DANA-FARBER CANCER INSTITUTE, INC. , GRAY, Nathanael, S. , CHOUCHANI, Edward , ZHANG, Tinghu , DARABEDIAN, Narek , JL, Wenzhi , CHE, Jianwei

发明人： GRAY, Nathanael, S. , CHOUCHANI, Edward , ZHANG, Tinghu , DARABEDIAN, Narek , JL, Wenzhi , CHE, Jianwei

IPC分类号： A61P35/00 , C07D265/36 , C07D413/04 , A61K31/538

摘要： The present disclosure relates to compounds of formula I that are capable of inhibiting creatine kinase. The present disclosure also relates to methods of treating cancer, such as hematological malignancies.