公开(公告)号：WO2011002694A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/040119

申请日：2010-06-26

Applicant: ABBOTT DIABETES CARE INC. ,  HELLER, Adam ,  FELDMAN, Benjamin, Jay ,  KARINKA, Shridhara, Alva ,  WANG, Yi ,  GALASSO, John, R.

Inventor： HELLER, Adam ,  FELDMAN, Benjamin, Jay ,  KARINKA, Shridhara, Alva ,  WANG, Yi ,  GALASSO, John, R.

IPC: A61B5/1468

CPC classification number: A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7445 ,  A61B2562/0295

Abstract: In aspects of the present disclosure, an auto turn on blood glucose monitoring unit including a calibration unit integrated with one or more components of an analyte monitoring system is provided. Also disclosed are methods, systems, devices and kits for providing the same.

Abstract translation: 在本公开的方面中，提供了包括与分析物监测系统的一个或多个部件集成的校准单元的自动转动血糖监测单元。 还公开了用于提供其的方法，系统，装置和套件。

公开(公告)号：WO2006033791A1

公开(公告)日：2006-03-30

申请号：PCT/US2005/030974

申请日：2005-08-31

Applicant: ABBOTT LABORATORIES ,  WANG, Yi ,  WATKIN, Jared, Lee ,  MACE, Chad, Harold ,  ZOCCHI, Michael, R. ,  KARINKA, Shridhara, Alva ,  TESS, Mark, E.

Inventor： WANG, Yi ,  WATKIN, Jared, Lee ,  MACE, Chad, Harold ,  ZOCCHI, Michael, R. ,  KARINKA, Shridhara, Alva ,  TESS, Mark, E.

IPC: A61B5/00 ,  G01N33/487

CPC classification number: G01N27/27 ,  A61B5/1486 ,  A61B2562/0295 ,  G01N27/3272 ,  G01N33/4875

Abstract: An article suitable for conducting one or more assays with an apparatus, e.g., a meter, for determining the presence or concentration of an analyte in a sample of biological fluid. The article contains a plurality of biosensors arranged in such a manner that each of the biosensors can be utilized before the article must be removed from the apparatus.

Abstract translation: 适于用仪器（例如仪表）进行一个或多个测定的用于确定生物流体样品中分析物的存在或浓度的物品。 所述制品包含多个生物传感器，所述生物传感器以这样的方式布置，即在所述制品必须从所述装置中取出之前，可以使用每个所述生物传感器。

公开(公告)号：WO2011002693A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/040118

申请日：2010-06-26

Applicant: ABBOTT DIABETES CARE INC. ,  HELLER, Adam ,  FELDMAN, Benjamin, Jay ,  KARINKA, Shridhara, Alva ,  WANG, Yi ,  GALASSO, John, R.

Inventor： HELLER, Adam ,  FELDMAN, Benjamin, Jay ,  KARINKA, Shridhara, Alva ,  WANG, Yi ,  GALASSO, John, R.

IPC: A61B5/1468

CPC classification number: G01N27/3274 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/7242 ,  A61B5/7445 ,  C12Q1/006 ,  G01N33/66 ,  G06F19/00

Abstract: In aspects of the present disclosure, a multi compatible or universal blood glucose monitoring unit including a calibration unit is integrated with one or more components of an analyte monitoring system to provide compatibility with in vitro test strip that require calibration code and test strips that do not require calibration code. Also disclosed are methods, systems, devices and kits for providing the same.

Abstract translation: 在本公开的方面，包括校准单元的多个兼容或通用的血糖监测单元与分析物监测系统的一个或多个组件集成，以提供与体外测试条的兼容性，其需要校准代码和测试条 需要校准代码。 还公开了用于提供其的方法，系统，装置和套件。

公开(公告)号：WO2011002692A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/040117

申请日：2010-06-26

Applicant: ABBOTT DIABETES CARE INC. ,  HELLER, Adam ,  FELDMAN, Benjamin, Jay ,  KARINKA, Shridhara, Alva ,  WANG, Yi ,  GALASSO, John, R.

Inventor： HELLER, Adam ,  FELDMAN, Benjamin, Jay ,  KARINKA, Shridhara, Alva ,  WANG, Yi ,  GALASSO, John, R.

IPC: G01N27/26

CPC classification number: A61B5/1495 ,  A61B5/0031 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1477 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7445 ,  A61B5/7455 ,  A61B5/746 ,  A61B17/3468 ,  A61B2017/3407 ,  A61B2017/3409 ,  A61B2560/0209 ,  A61B2560/0475 ,  A61B2562/0271 ,  A61B2562/0295 ,  A61B2562/085 ,  A61B2562/125 ,  G01N27/3272 ,  G01N27/3273

Abstract: In aspects of the present disclosure, a no coding blood glucose monitoring unit including a calibration unit is integrated with one or more components of an analyte monitoring system to provide compatibility with in vitro test strip that do not require a calibration code is provided. Also disclosed are methods, systems, devices and kits for providing the same.

Abstract translation: 在本公开的方面，包括校准单元的无编码血糖监测单元与分析物监测系统的一个或多个组分集成，以提供与不需要校准代码的体外测试条的兼容性。 还公开了用于提供其的方法，系统，装置和套件。

公开(公告)号：WO2008134587A1

公开(公告)日：2008-11-06

申请号：PCT/US2008/061680

申请日：2008-04-25

Applicant: ABBOTT DIABETES CARE, INC. ,  WANG, Yi ,  KARINKA, Shridhara, Alva ,  GALASSO, John, R.

Inventor： WANG, Yi ,  KARINKA, Shridhara, Alva ,  GALASSO, John, R.

IPC: G01N33/487 ,  C12Q1/00

CPC classification number: C12Q1/006 ,  G01N27/3272

Abstract: A test strip including a reagent end for receiving a body fluid sample and an insertion end which is received at a test strip receptacle slot of a measuring device, the insertion end including one or more on-strip indicators for indicating to a measuring device that the test strip has been inserted into the device so that the device will power-up in preparation to perform a test, and the one or more on-strip indicators having a distinct pattern indicating whether calibration is automatic or whether the user needs to input calibration information to the said device, and corresponding methods are disclosed.

Abstract translation: 一种测试条，包括用于接收体液样品的试剂端和容纳在测量装置的测试条插座槽处的插入端，所述插入端包括一个或多个带状指示器，用于向测量装置指示， 测试条被插入设备中，使得设备将准备启动以进行测试，并且一个或多个带状指示器具有指示校准是自动的还是用户是否需要输入校准信息的不同模式 到所述装置，并且公开了相应的方法。

公开(公告)号：WO2012149410A2

公开(公告)日：2012-11-01

申请号：PCT/US2012/035580

申请日：2012-04-27

Applicant: ABBOTT DIABETES CARE INC. ,  BHOGAL, John ,  KARINKA, Shridhara Alva ,  HENNING, Timothy P. ,  CUNNINGHAM, David ,  HOSS, Udo ,  NAEGELI, Andrew H. ,  LATOUR, John

Inventor： BHOGAL, John ,  KARINKA, Shridhara Alva ,  HENNING, Timothy P. ,  CUNNINGHAM, David ,  HOSS, Udo ,  NAEGELI, Andrew H. ,  LATOUR, John

IPC: G01N30/96 ,  A61B5/00 ,  G01N33/00

CPC classification number: A61B10/0045 ,  A61B5/14503 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1495 ,  A61B2010/008 ,  G01N30/96

Abstract: Provided are methods of measuring analyte concentrations in interstitial fluid samples, methods of determining accuracy of subcutaneously implantable analyte sensors, methods of manufacturing and determining calibration factors for subcutaneously implantable analyte sensors, as well as subcutaneously implantable analyte sensors manufactured according to the described methods and having a high level of accuracy. Methods of determining the concentration of an analyte in a bodily sample, and methods of extracting interstitial fluid are also provided.

Abstract translation: 提供了测量间质液样品中分析物浓度的方法，确定皮下可植入分析物传感器的准确性的方法，制备和确定皮下可植入分析物传感器的校准因子的方法，以及根据所述方法制造的皮下可植入的分析物传感器，并具有 高精度。 还提供了确定身体样品中分析物浓度的方法和提取组织液的方法。

公开(公告)号：WO2008134561A1

公开(公告)日：2008-11-06

申请号：PCT/US2008/061642

申请日：2008-04-25

Applicant: ABBOTT DIABETES CARE INC. ,  KARINKA, Shridhara, Alva ,  WANG, Yi

Inventor： KARINKA, Shridhara, Alva ,  WANG, Yi

IPC: G01N33/487

CPC classification number: G01N33/48771

Abstract: A meter and sensors, for use in combination, where no calibration code has to be entered by the user or is read by the meter. The meter is configured with a predetermined slope and y-intercept built into the meter. If the slope and y-intercept of the sensor are within a predetermined area or grid, or otherwise close to the slope and y-intercept of the meter, the batch of sensors is acceptable for use with that meter for providing accurate analyte concentration results.

Abstract translation: 用于组合使用的仪表和传感器，其中不需要由用户输入校准代码或由仪表读取。 仪表配置有内置在仪表中的预定斜率和y截距。 如果传感器的斜率和y截距在预定的区域或网格内，或者以其他方式接近仪表的斜率和y截距，则该批传感器可接受用于该仪表以提供准确的分析物浓度结果。

公开(公告)号：WO2012149410A3

公开(公告)日：2014-04-17

申请号：PCT/US2012035580

申请日：2012-04-27

Applicant: ABBOTT DIABETES CARE INC ,  BHOGAL JOHN ,  KARINKA SHRIDHARA ALVA ,  HENNING TIMOTHY P ,  CUNNINGHAM DAVID ,  HOSS UDO ,  NAEGELI ANDREW H ,  LATOUR JOHN

Inventor： BHOGAL JOHN ,  KARINKA SHRIDHARA ALVA ,  HENNING TIMOTHY P ,  CUNNINGHAM DAVID ,  HOSS UDO ,  NAEGELI ANDREW H ,  LATOUR JOHN

IPC: A61B10/02

CPC classification number: A61B10/0045 ,  A61B5/14503 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1495 ,  A61B2010/008 ,  G01N30/96

Abstract: Provided are methods of measuring analyte concentrations in interstitial fluid samples, methods of determining accuracy of subcutaneously implantable analyte sensors, methods of manufacturing and determining calibration factors for subcutaneously implantable analyte sensors, as well as subcutaneously implantable analyte sensors manufactured according to the described methods and having a high level of accuracy. Methods of determining the concentration of an analyte in a bodily sample, and methods of extracting interstitial fluid are also provided.

Abstract translation: 提供了测量间质液样品中分析物浓度的方法，确定皮下可植入分析物传感器的准确性的方法，制备和确定皮下可植入分析物传感器的校准因子的方法，以及根据所述方法制造的皮下可植入分析物传感器，并具有 高精度。 还提供了确定身体样品中分析物浓度的方法和提取组织液的方法。

公开(公告)号：WO2011025693A1

公开(公告)日：2011-03-03

申请号：PCT/US2010/045755

申请日：2010-08-17

Applicant: ABBOTT DIABETES CARE INC. ,  WANG, Yi ,  KARINKA, Shridhara Alva ,  FELDMAN, Benjamin J.

Inventor： WANG, Yi ,  KARINKA, Shridhara Alva ,  FELDMAN, Benjamin J.

IPC: G01N33/48 ,  G01N33/52

CPC classification number: G01N27/3272 ,  B32B37/12 ,  B32B37/14 ,  B32B37/18 ,  B32B38/0004 ,  B32B2535/00 ,  G01N27/327 ,  Y10T156/1052

Abstract: The present disclosure provides small volume analyte sensors having large sample fill ports, supported analyte sensors, analyte sensors having supported tip protrusions and methods of making and using same.

Abstract translation: 本公开提供具有大样品填充端口的小体积分析物传感器，支持的分析物传感器，具有支撑的尖端突起的分析物传感器及其制造和使用方法。

公开(公告)号：WO2009129108A1

公开(公告)日：2009-10-22

申请号：PCT/US2009/039952

申请日：2009-04-08

Applicant: ABBOTT DIABETES CARE INC. ,  FORROW, Nigel, John ,  KARINKA, Shridhara, Alva

Inventor： FORROW, Nigel, John ,  KARINKA, Shridhara, Alva

IPC: C12Q1/00

CPC classification number: C12Q1/001 ,  C12Q1/004 ,  C12Q1/006

Abstract: The disclosure provides for reagent compositions for biosensors comprising release polymers, methods of making such biosensors and films of reagent compositions comprising release polymers. The reagent compositions comprise a release polymer and an effective analyte detecting amount of an enzyme an enzyme cofactor and a redox compound capable of acting in a biosensor as (i) a redox mediator associated with a working electrode (ii) a redox couple associated with a reference electrode or (iii) the redox mediator associated with the working electrode and the redox couple for the reference electrode.

Abstract translation: 本公开提供了用于包含释放聚合物的生物传感器的试剂组合物，制备这种生物传感器的方法和包含释放聚合物的试剂组合物的膜。 试剂组合物包含释放聚合物和有效分析物检测量酶，酶辅助因子和能够在生物传感器中起作用的氧化还原化合物，因为（i）与工作电极相关联的氧化还原介体（ii）与 参比电极或（iii）与工作电极相关的氧化还原介体和用于参比电极的氧化还原对。