公开(公告)号：WO2021222667A1

公开(公告)日：2021-11-04

申请号：PCT/US2021/030020

申请日：2021-04-29

Applicant: ABBOTT LABORATORIES ,  ARAI, Yoshiyuki ,  KOMORI, Tomotaka

Inventor： YOSHIMURA, Toru

IPC: B01L3/00 ,  G01N35/00 ,  B01L2200/0621 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/0829 ,  B01L2300/0896 ,  B01L2400/043 ,  B01L3/502715 ,  B01L3/502746 ,  B01L3/502761

Abstract: Sample analysis systems and methods using assay surfaces, assay processing units (APUs), assay processing systems (APSs), and laboratory systems are disclosed. An assay surface includes a sample processing component comprising a plurality of regions, including at least one wash region and at least one storage region configured to hold a plurality of solid supports moveable through the regions under a magnetic force, and a detection component configured to receive the solid supports. An APU includes an assay surface receiving component, a magnetic element configured to generate a moveable magnetic field, and one or more processors configured to move the magnetic field. An APS includes one or more assay surfaces and an APU. A laboratory system includes one or more APSs and a controller for parallel processing. Sample processing and detection methods are disclosed with a reduced sample volume and/or shortened processing time and/or higher sensitivity.

公开(公告)号：WO2023081300A2

公开(公告)日：2023-05-11

申请号：PCT/US2022/048856

申请日：2022-11-03

Applicant: ABBOTT LABORATORIES ,  YOSHIMURA, Toru ,  ARAI, Yoshiyuki ,  KOMORI, Tomotaka ,  CHIBA, Ryotaro ,  HUFF, Jeffrey

Inventor： YOSHIMURA, Toru ,  ARAI, Yoshiyuki ,  KOMORI, Tomotaka ,  CHIBA, Ryotaro ,  HUFF, Jeffrey

IPC: B01L3/00

Abstract: Sample analysis systems and methods using assay surfaces, assay processing units (APUs), assay processing systems (APSs), and laboratory systems are disclosed. An assay surface includes a sample processing component comprising a plurality of regions, including at least one wash region and at least one storage region configured to hold a plurality of solid supports moveable through the regions under a magnetic force, and a detection component configured to receive the solid supports. An APU includes an assay surface receiving component, a magnetic element configured to generate a moveable magnetic field, and one or more processors configured to move the magnetic field. An APS includes one or more assay surfaces and an APU. A laboratory system includes one or more APSs and a controller for parallel processing. Sample processing and detection methods are disclosed with a reduced sample volume and/or shortened processing time and/or higher sensitivity.