摘要:
The disclosed methods use a multi-phase system to separate samples according to the density of an analyte of interest. The method uses a multi-phase system that comprises two or more phase-separated solutions and a phase component such as a surfactant or polymer. The density of the analyte of interest differs from the densities of the rest of the sample. The density of the analyte of interest is substantially the same as one or more phases. Thus, when the sample is introduced to the multi-phase system, the analyte of interest migrates to the phase having the same density as the analyte of interest, passing through one or more phases sequentially.
摘要:
A method of analyzing or separating dry analytes is described, comprising: a) providing a mixture comprising: a dry sample comprising one or more dry analytes; a first and second phase components selected from the group consisting of a polymer, a surfactant, and combinations thereof, wherein at least one of the first and second phase components comprises a polymer; one or more solvents; b) allowing the mixture to phase-separate into a multi-phase system comprising: two or more phases including at least a first phase comprising the first phase component, a second phase comprising the second phase component, wherein the first and second phases are in contact with and phase-separated from each other; and each of the two or more phases is phase-separated from other phases and has an upper boundary and a lower boundary; and the one or more dry analytes located at locations characteristic of their density.
摘要:
The present disclosure presents systems and methods for maintaining identification of network devices sending or traversing a network packet en route to an intermediary device deployed between a source and a destination network device. An intermediary may receive an acknowledgement packet comprising an option field identified by an option number for a transport layer connection established via intermediary. The acknowledgement packet may comprise overlay network data that identifies IP addresses of the originating network device and host network devices intercepting and forwarding the network packet to the intermediary. The intermediary device may determine the option number for the option field from which to obtain the overlay network data identifying IP addresses. The intermediary device may receive a second request of the client to access the server via the transport layer connection and insert IP addresses from the overlay network data into an application layer protocol header of the second request forwarded to the server.
摘要:
The present invention provides an improved process for the preparation of candesartan and pharmaceutically acceptable salts and esters thereof for use in the treatment of hypertension and related diseases. Specifically, it refers to the deprotection of tetrazolyl -protecting group of candesartan or its derivative in the presence of iodine in one or more alcoholic solvents.
摘要:
The invention provides methods for preventing loss and augmenting regeneration of skeletal muscle by decreasing the activity of the TWEAK/Fn14 system.
摘要:
The present invention provides an improved process for the preparation of candesartan and pharmaceutically acceptable salts and esters thereof for use in the treatment of hypertension and related diseases. Specifically, it refers to the deprotection of tetrazolyl -protecting group of candesartan or its derivative in the presence of iodine in one or more alcoholic solvents.
摘要:
A macroporous polymer matrix for administrating one or more active ingredient to a subject in need thereof is provided herein. The polymer matrix comprises a polymer cross-linked by polyethylene glycol diacrylate wherein the polymer is polyvinyl pyrrolidone or a combination of polyvinyl pyrrolidone and polyvinyl alcohol.
摘要:
Disclosed are complexes of an antipneumocystic compound and an antimalarial compound, processes for their preparation, pharmaceutical compositions and methods of using said complexes or compositions for the treatment and/or prophylaxis of parasitic infections.
摘要:
The present invention discloses an electronic horn for a vehicle having a housing sub-assembly; a diaphragm sub-assembly; wherein a chip on board circuit is riveted to a terminal block outside the housing and the chip on board circuit has clipping means for eliminating surge voltages.
摘要:
A query cache stores queries and corresponding results of the queries, the results of the queries being derived from a primary store. A differential store stores a pointer to data of the primary store which has changed and which affects the result of the queries stored in the query store. A new query may be satisfied by accessing the corresponding query in the query store and determining, by reference to the differential store, whether data relating to the query in the primary store has changed since the query store was compiled and, completing the new query, by accessing the corresponding data in the primary store, if applicable. Data in the differential store may be arranged and partitioned according to labels. The partitioning may be varied according to predetermined rules.