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公开(公告)号:WO2022168727A1
公开(公告)日:2022-08-11
申请号:PCT/JP2022/003051
申请日:2022-01-27
Applicant: テルモ株式会社
Inventor: 五十嵐政嗣
Abstract: サンプリング方法は、細胞培養デバイス(200)からサンプリング流路(30)にサンプルを流通させて第2センサ(28)及びガス濃度センサ(62)でサンプル中の所定成分の濃度を測定するサンプリング工程と、サンプリング工程の後で、サンプリング流路(30)に洗浄液を流通させて第2センサ(28)及びガス濃度センサ(62)に洗浄液を流通させる洗浄工程と、洗浄工程の後で、ガス濃度センサ(62)の内部に残存している洗浄液を空気に置換する空気導入工程と、を含む。
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公开(公告)号:WO2022052423A1
公开(公告)日:2022-03-17
申请号:PCT/CN2021/077403
申请日:2021-02-23
Applicant: 倍仪昇智能科技(苏州)有限公司
Abstract: 本申请提供一种微生物检测前处理系统,其包括样品均质单元、梯度稀释单元、培养皿输入单元、处理转移单元和培养皿输出单元,该样品均质单元将样品容器中的样品定量稀释后均质,通过液体转移装置将样品容器中的样品溶液转移至该梯度稀释单元进行梯度稀释,该培养皿输入单元将培养皿输入至该处理转移单元,通过液体转移装置将梯度稀释后的样品溶液注入培养皿进行前处理,并转移至培养皿输出单元。本申请还提供一种微生物检测前处理方法。本申请为微生物检测的前处理提供自动化解决方案,提高处理效率,为微生物检测实验提供更精准的前期准备。
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公开(公告)号:WO2021250274A1
公开(公告)日:2021-12-16
申请号:PCT/EP2021/065932
申请日:2021-06-14
Inventor: ALCAMI PERTEJO, Antonio , RASTROJO LASTRAS, Alberto
IPC: C12Q1/70 , C12Q1/04 , C12Q1/24 , C12Q1/6888 , C12M1/12 , G01N33/497 , G01N1/22 , C12Q1/6806 , C12M37/00 , G01N1/2205 , G01N1/2273 , G01N2001/2223
Abstract: The present invention refers to a device comprising polytetrafluorethylene (PTFE) filters and the use of the same for collecting, detecting and identifying organisms present in air ecosystems. The invention also provides a method suitable for the capture, detection and identification of whole airborne biological particles, including viruses and other important air pathogens, which involves the use of the device. This method allows toperform organism, preferably viral, metagenomics to sequence all DNA and RNA organisms captured in the filters. This methodology may be used to detect, for instance, SARS-CoV2 particles in air samples.
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公开(公告)号:WO2021229564A1
公开(公告)日:2021-11-18
申请号:PCT/IL2021/050528
申请日:2021-05-10
Applicant: NOVAMED LTD.
Inventor: KATZ, Emil , PORATH, Gadi
Abstract: The present invention pertains to a sampling apparatus comprising a sample container for containing a liquid sample, the sample container optionally includes a container lid; and a dip element for retrieving a liquid sample for testing from the sample container, wherein the sample container comprises container graduations and container indicia; the dip element comprises dip element graduations and dip element indicia, the dip element indicia and graduations spatially correspond in reverse order to the container indicia and graduations of the sample container, to thereby aid in determining the proper depth of dipping the dip element into the liquid sample within the sample container when retrieving a sample for testing.
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公开(公告)号:WO2021190340A1
公开(公告)日:2021-09-30
申请号:PCT/CN2021/080829
申请日:2021-03-15
Applicant: 康博医创股份有限公司
IPC: C12Q1/02 , C12Q1/24 , A61M1/3496 , B01D2239/0407 , B01D2239/0478 , B01D39/16 , C12Q1/04 , G01N33/56911
Abstract: 本发明提供一种用于富集和检测生物样品中微生物的方法及装置,使得生物样品可通过高分子聚合物改质的基材进行过滤,改质的基材具有高度专一性的有核细胞捕捉或分离能力,并且其中的微生物可通过或流过高分子聚合物改质的基材进入到滤液中,从而在有核细胞减除过程中富集生物样品中的微生物(包括细菌、霉浆菌、真菌、病毒与孢子等),进而降低因有核细胞(如白细胞)所造成的病源检验干扰。
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6.
公开(公告)号:WO2021130339A1
公开(公告)日:2021-07-01
申请号:PCT/EP2020/087821
申请日:2020-12-23
Applicant: RESISTELL AG
Inventor: DELARZE, Eric , LURASCHI, Amanda , SWIATKOWSKI, Michal , WIELGOSZEWSKI, Grzegorz , SIEGERT, Michael
Abstract: A kit-of-parts for attaching a preferably biological object and/or a non-biological object, e.g. a bacterial cell, on a substrate (1, 1'), e.g. a cantilever for use in atomic force microscopy (AFM) comprises (i) at least a first solution comprising at least one first compound, wherein the first compound is at least one of a gelling agent, a gellable agent, and a thickening agent, e.g. agar, Nation, chitosan or polyacrylamide, and (ii) at least a first substrate (1, 1') comprising a surface (2, 2'), wherein at least a first part (3, 3') of the surface (2, 2') of the substrate (1, 1 ') is preferably functionalized, e.g. using glutaraldehyde. The first solution is suitable for forming at least a first dispersion of the at least one biological object and/or non-biological object. The first dispersion and the preferably functionalized surface (3, 3') of the substrate (1, T) are suitable for attaching the object on the surface (3, 3') of the substrate (1, T).
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公开(公告)号:WO2021077456A1
公开(公告)日:2021-04-29
申请号:PCT/CN2019/114518
申请日:2019-10-31
Applicant: 中山大学
Abstract: 本发明提供一种用于微生物酶活测试的过滤装置及方法,该装置包括用于提供待过滤液体的供液机构、用于收集滤液的收集机构,供液机构包括上连接台,收集机构包括收集容器,收集容器上设有用于放置滤膜的下连接台,上连接台、下连接台可拆卸连接,上连接台、下连接台上贯穿设有至少一个过滤通道,供液机构中的待过滤液体穿过过滤通道以及滤膜,进入收集机构的集液腔,滤膜上富集截留物。本发明的装置通过过滤的方式富集细胞,所需过滤的细胞液用量显著减少,单次过滤样品的数量显著增多,进而使得后续酶活测试时所需的底物显著减少,该装置及方法实现高通量过滤,操作简单,造价低廉,便于推广应用。
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8.
公开(公告)号:WO2021046496A1
公开(公告)日:2021-03-11
申请号:PCT/US2020/049608
申请日:2020-09-06
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor: GRIFFING, Lawrence , KUMAR, Krishna
Abstract: In an embodiment, the present disclosure pertains to a method of inhibiting seed germination or modifying seedling growth. Generally, the method includes encapsulating or solubilizing sterols in an encapsulating agent and exposing a plant to the encapsulated or solubilized sterol in either a liquid or powdered- water-soluble form. In an additional embodiment, the present disclosure pertains to a composition that includes a sterol in an encapsulating agent in either a liquid or powdered- water- soluble form.
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9.
公开(公告)号:WO2021046343A1
公开(公告)日:2021-03-11
申请号:PCT/US2020/049394
申请日:2020-09-04
Applicant: TELEFLEX MEDICAL INCORPORATED
Inventor: ULRICH, Robert , WAGNER, Victoria E. , MCDANIEL, Lauren
IPC: C12Q1/04 , C12Q1/24 , G01N33/543
Abstract: A lysis solution for lysing microorganisms in a biological sample includes 2 mM to 16 mM of a Quanidinium thiocyanate/guanidine thiocyanate, 20 µM to 160 µM of a Tris HCL, pH 8.5, 6 µM to 48 µM of a Magnesium chloride, 35 µM to 280 µM of a Potassium chloride, and 0.1% v/v to 1.0% v/v of an octylphenoxypolyethoxyethanol.
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公开(公告)号:WO2020260583A1
公开(公告)日:2020-12-30
申请号:PCT/EP2020/068027
申请日:2020-06-26
Applicant: UNIVERSITEIT GENT
Inventor: NAUWYNCK, Hans , THEUNS, Sebastiaan , ARNOUTS, Sven
Abstract: The present invention is directed to a sampling device for the collection and isolation of a biological specimen from a sample or from a location. The sampling device comprises a swab tip and a support body wherein the support body has a hollow conformation with a first end and a second end and wherein said first end is in fluid connection with the internal surface of the swab tip. Typical for the present sampling device is that the swab tip comprises a filter material with a pore size that decreases from the external surface of the swab tip to the internal surface of the swab tip. The invention further also discloses the use of said sampling device and a method for the collection and isolation of a biological specimen.
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