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公开(公告)号：WO2004063719A2
公开(公告)日：2004-07-29
申请号：PCT/US2004/000774
申请日：2004-01-13
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN , LUBMAN, David, M. , CHINNAIYAN, Arul, M. , SREEKUMAR, Arun , LAXMAN, Bharathi , YAN, Fang
IPC分类号： G01N
CPC分类号： C07K1/047 , C07K14/4748 , C07K17/02 , G01N30/02 , G01N33/6818 , B01D15/325
摘要： The present invention relates to automated methods, systems, and apparatuses protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
摘要翻译： 本发明涉及自动化方法，系统和装置蛋白质分离和分析。 特别地，本发明提供了用于蛋白质样品的分离，鉴定和表征的自动化系统。 因此，本发明提供了用于分离和分析含有多种蛋白质（例如细胞）的样品的改进方法。
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公开(公告)号：WO2004063719A3
公开(公告)日：2004-09-16
申请号：PCT/US2004000774
申请日：2004-01-13
申请人： UNIV MICHIGAN , LUBMAN DAVID M , CHINNAIYAN ARUL M , SREEKUMAR ARUN , LAXMAN BHARATHI , YAN FANG
发明人： LUBMAN DAVID M , CHINNAIYAN ARUL M , SREEKUMAR ARUN , LAXMAN BHARATHI , YAN FANG
CPC分类号： C07K1/047 , C07K14/4748 , C07K17/02 , G01N30/02 , G01N33/6818 , B01D15/325
摘要： The present invention relates to automated methods, systems, and apparatuses protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
摘要翻译： 本发明涉及自动化方法，系统和装置蛋白质分离和分析。 特别地，本发明提供了用于蛋白质样品的分离，鉴定和表征的自动化系统。 因此，本发明提供了用于分离和分析含有多种蛋白质（例如细胞）的样品的改进方法。
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公开(公告)号：WO2006012646A3
公开(公告)日：2007-03-01
申请号：PCT/US2005027223
申请日：2005-07-29
IPC分类号： G01N33/53 , C12N15/09 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/48 , G01N33/50 , G01N33/566 , G01N33/574
CPC分类号： G01N33/57434 , C07K16/3069 , C07K16/40 , C12Q1/533 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , Y10S435/96 , Y10S436/813
摘要： The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. The present invention also provides novel markers useful for the diagnosis, characterization, and treatment of prostrate cancers. In particular, the present invention provides methods and compositions for the use of a-methylacyl-CoA racemase (AMACR) as a marker for prostrate cancer detection and prognosis.
摘要翻译： 本发明涉及用于癌症诊断的组合物和方法，包括但不限于癌症标志物。 特别地，本发明提供与前列腺癌相关的基因表达谱。 本发明还提供了可用于诊断，表征和治疗前列腺癌的新型标志物。 特别地，本发明提供了使用α-甲酰基-CoA消旋酶（AMACR）作为前列腺癌检测和预后的标记物的方法和组合物。
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公开(公告)号：WO2006012646A2
公开(公告)日：2006-02-02
申请号：PCT/US2005/027223
申请日：2005-07-29
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN , RUBIN, Mark, A. , CHINNAIYAN, Arul, M. , LAXMAN, Bharathi , SREEKUMAR, Arun
IPC分类号： G01N33/574 , C12Q1/48 , C07K16/40
CPC分类号： G01N33/57434 , C07K16/3069 , C07K16/40 , C12Q1/533 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , Y10S435/96 , Y10S436/813
摘要： The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. The present invention also provides novel markers useful for the diagnosis, characterization, and treatment of prostrate cancers. In particular, the present invention provides methods and compositions for the use of α-methylacyl-CoA racemase (AMACR) as a marker for prostrate cancer detection and prognosis.
摘要翻译： 本发明涉及用于癌症诊断的组合物和方法，包括但不限于癌症标志物。 特别地，本发明提供与前列腺癌相关的基因表达谱。 本发明还提供了可用于诊断，表征和治疗前列腺癌的新型标志物。 特别地，本发明提供了使用α-甲酰基-CoA消旋酶（AMACR）作为前列腺癌检测和预后的标记物的方法和组合物。
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