公开(公告)号：WO2006071095A1

公开(公告)日：2006-07-06

申请号：PCT/KR2005/004664

申请日：2005-12-30

申请人： SK CHEMICALS, CO., LTD. ,  LEADGENEX INC. ,  INDUSTRY ACADEMIC COOPERATION FOUNDATION OF KYUNGHEE UNIVERSITY ,  LEE, Nam Kyu ,  LEE, Jun Won ,  LEE, Sukho ,  IM, Guang-Jin ,  HAN, Hye Young ,  KIM, Tae Kon ,  KIM, Yong Hyuk ,  KWAK, Wie-Jong ,  KIM, Sang Woong ,  HA, Joohun ,  KIM, Eon Kyum ,  LEE, Jung Kyu ,  YOO, Choong Yeul ,  LEE, Dae Yeon

发明人： LEE, Nam Kyu ,  LEE, Jun Won ,  LEE, Sukho ,  IM, Guang-Jin ,  HAN, Hye Young ,  KIM, Tae Kon ,  KIM, Yong Hyuk ,  KWAK, Wie-Jong ,  KIM, Sang Woong ,  HA, Joohun ,  KIM, Eon Kyum ,  LEE, Jung Kyu ,  YOO, Choong Yeul ,  LEE, Dae Yeon

IPC分类号： C07D239/94 ,  A61K31/517 ,  A61P3/04 ,  A61P3/10

CPC分类号： C07D413/12 ,  C07D239/88 ,  C07D239/93 ,  C07D239/94 ,  C07D401/12 ,  C07D403/04 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12

摘要： The present invention relates to novel quinazoline derivatives effective in lowering blood glucose level and body weight, and a medicine for treatment and/ or prevention of diabetes and/ or obesity, which comprises the compound as an active ingredient.

摘要翻译： 本发明涉及有效降低血糖水平和体重的新型喹唑啉衍生物，以及用于治疗和/或预防糖尿病和/或肥胖症的药物，其包含该化合物作为活性成分。

公开(公告)号：WO2006070984A1

公开(公告)日：2006-07-06

申请号：PCT/KR2005/001833

申请日：2005-06-15

申请人： SK CHEMICALS, CO., LTD. ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  GONG, Young-Dae ,  SEO, Jin-Soo ,  JEON, Moon-Kook ,  KWAK, Wie-Jong ,  CHO, Yong-Baik ,  LEE, Nam Kyu ,  LEE, Eun Ju ,  LEE, Jung Bum ,  LEE, Jun Won ,  LEE, Sukho ,  DONG, Mi-Sook ,  KIM, Jeong-Ran

发明人： GONG, Young-Dae ,  SEO, Jin-Soo ,  JEON, Moon-Kook ,  KWAK, Wie-Jong ,  CHO, Yong-Baik ,  LEE, Nam Kyu ,  LEE, Eun Ju ,  LEE, Jung Bum ,  LEE, Jun Won ,  LEE, Sukho ,  DONG, Mi-Sook ,  KIM, Jeong-Ran

IPC分类号： A61K31/353 ,  C07D311/04 ,  A61P1/16

CPC分类号： C07D311/70

摘要： The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-β receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof

摘要翻译： 本发明涉及一种对TGF-β受体具有优异活性的新型苯并吡喃衍生物，可有效用作肝脏疾病的预防和治疗药物，以及若干纤维样天然酶，如肝纤维化，肝硬化，肺纤维化，皮肤硬化，肾小球 纤维化等; 及其药物用途