SIMILAR DATA SET IDENTIFICATION
    1.
    发明申请

    公开(公告)号:WO2022016363A1

    公开(公告)日:2022-01-27

    申请号:PCT/CN2020/103233

    申请日:2020-07-21

    Abstract: The present disclosure is related to a method, an electronic device, and a system for identifying similar data sets from a plurality of data sets. The method comprises: converting the plurality of data sets into a plurality of data sequences, respectively, each of the data sequences being a sequence of one or more data objects; determining a feature vector for each of the data objects such that each of the plurality of data sets corresponds to a sequence of one or more feature vectors; and clustering the plurality of data sets into one or more data clusters based on similarities between their corresponding sequences of feature vectors, each of the data clusters being a cluster of similar data sets.

    METHODS OF IDENTIFYING A PATIENT POPULATION
    3.
    发明申请
    METHODS OF IDENTIFYING A PATIENT POPULATION 审中-公开
    识别患者人口的方法

    公开(公告)号:WO2012116260A1

    公开(公告)日:2012-08-30

    申请号:PCT/US2012/026460

    申请日:2012-02-24

    CPC classification number: G01N33/573 G01N2333/96486 G01N2800/52

    Abstract: Provided herein is a method for identifying a patient as a candidate for treatment with an aggrecanase inhibitor. Also provided is a method of evaluating the effectiveness of an aggrecanase inhibitor. In one aspect the present invention is directed to a method for identifying a patient as a candidate for treatment with an aggrecanase inhibitor comprising: isolating a biological sample from a patient; and detecting in the sample the presence or absence of at least one aggrecan degradation product; wherein the presence of at least one aggrecan degradation product in the biological sample indicates that the patient is a good candidate for treatment.

    Abstract translation: 本文提供了用于鉴定患者作为用聚集蛋白聚糖蛋白聚糖酶抑制剂治疗的候选者的方法。 还提供了评估聚集蛋白聚糖蛋白聚糖酶抑制剂的有效性的方法。 一方面,本发明涉及用于鉴定患者作为用聚集蛋白聚糖蛋白聚糖蛋白酶抑制剂治疗的候选物的方法,其包括:从患者分离生物样品; 并在样品中检测是否存在至少一种聚集蛋白聚糖降解产物; 其中生物样品中存在至少一种聚集蛋白聚糖降解产物表明患者是治疗的良好候选者。

    CHEMICAL PLANARIZATION OF COPPER WAFER POLISHING
    4.
    发明申请
    CHEMICAL PLANARIZATION OF COPPER WAFER POLISHING 审中-公开
    铜波抛光的化学平面化

    公开(公告)号:WO2011152966A3

    公开(公告)日:2012-03-29

    申请号:PCT/US2011036019

    申请日:2011-05-11

    CPC classification number: H01L21/3212 B24B37/044 C09G1/04 H01L21/7684

    Abstract: Embodiments described herein relate to removing material from a substrate. More particularly, the embodiments described herein relate to polishing or planarzing a substrate by a chemical mechanical polishing process. In one embodiment, a method of chemical mechanical polishing (CMP) of a substrate is provided. The method comprises exposing a substrate having a conductive material layer formed thereon to a polishing solution comprising phosphoric acid, one or more chelating agents, one or more corrosion inhibitors, and one or more oxidizers, forming a passivation layer on the conductive material layer, providing relative motion between the substrate and a polishing pad and removing at least a portion of the passivation layer to expose a portion of the underlying conductive material layer, and removing a portion of the exposed conductive material layer.

    Abstract translation: 本文所述的实施例涉及从衬底去除材料。 更具体地,本文所述的实施例涉及通过化学机械抛光工艺抛光或平面化衬底。 在一个实施例中,提供了基板的化学机械抛光(CMP)的方法。 该方法包括将其上形成有导电材料层的基底暴露于包含磷酸,一种或多种螯合剂,一种或多种腐蚀抑制剂和一种或多种氧化剂的抛光溶液,在导电材料层上形成钝化层,提供 衬底和抛光垫之间的相对运动,并移除钝化层的至少一部分以暴露下面的导电材料层的一部分,以及去除暴露的导电材料层的一部分。

    A METHOD OF FABRICATING STRUCTURED PARTICLES COMPOSED OF SILICON OR A SILICON-BASED MATERIAL AND THEIR USE IN LITHIUM RECHARGEABLE BATTERIES
    5.
    发明申请
    A METHOD OF FABRICATING STRUCTURED PARTICLES COMPOSED OF SILICON OR A SILICON-BASED MATERIAL AND THEIR USE IN LITHIUM RECHARGEABLE BATTERIES 审中-公开
    制备由硅或基于硅的材料组成的结构化颗粒的方法及其在锂可充电电池中的使用方法

    公开(公告)号:WO2011124893A2

    公开(公告)日:2011-10-13

    申请号:PCT/GB2011/000546

    申请日:2011-04-08

    CPC classification number: C23F1/16 C09K13/08 H01L21/30604 H01M4/0492 H01M4/38

    Abstract: The present invention provides a method for treating silicon to form pillars, especially for use as the active anode material in Li-ion batteries. The process is simple to operate on a commercial scale since it uses a solution containing only a small number of ingredients whose concentration needs to be controlled and it can be cheaper to operate than previous processes. The solution comprises: 0.01 to 5M HF 0.002 to 0.2M of metal ions capable of nucleating on and foirning a porous layer comprising regions of elemental metal on the silicon surface; 0.001 to 0.7M of an oxidant selected from the group O 2 , 0 3 , H 2 O 2 , the acid, ammonium or alkali metal salt of NO 3 - , S 2 O 8 2- , NO 2 - , B 4 O 7 2- and C1O 4 - or a mixture thereof.. The treated silicon is suitably removed from the solution.

    Abstract translation: 本发明提供一种处理硅以形成柱状物的方法,特别是用作锂离子电池中的活性阳极材料。 该方法在商业规模上操作简单,因为它使用仅含少量成分的溶液,其浓度需要被控制,并且可以比以前的方法操作更便宜。 该溶液包括:0.01至5M HF 0.002至0.2M的能够在硅表面上包含元素金属区域的多孔层上成核并形成的金属离子; 0.001〜0.7M的选自O 2,O 3,H 2 O 2,NO 3 - ,S 2-8 2-,NO 2 - ,B 4 O 7 2-和C 1-4 - 的酸,铵或碱金属盐的氧化剂或其混合物。 从溶液中适当地除去硅。

    A METHOD OF FABRICATING STRUCTURED PARTICLES COMPOSED OF SILICON OR A SILICON-BASED MATERIAL
    6.
    发明申请
    A METHOD OF FABRICATING STRUCTURED PARTICLES COMPOSED OF SILICON OR A SILICON-BASED MATERIAL 审中-公开
    制备由硅或基于硅的材料组成的结构化颗粒的方法

    公开(公告)号:WO2010040986A1

    公开(公告)日:2010-04-15

    申请号:PCT/GB2009/002351

    申请日:2009-10-02

    CPC classification number: H01M4/134 C09K13/08 H01M4/049 H01M10/052 Y02E60/122

    Abstract: The present invention provides a process for etching silicon to form pillars, which may be used as an anode material in a Li-ion battery; the process involves depositing silver onto silicon as part of the etching procedure. An etched silicon particle is shown in Figure 1. The silver present after the silicon has been etched can be removed by treatment with nitric acid. This removed silver can be recycled, thereby reducing the costs of the overall process. In one embodiment, the process comprises: - treating silicon, e.g. granules or bulk material, with an etching solution comprising HF, Ag+ ions and nitrate ions, thereby etching the silicon to form silicon having etched pillars on its surface; the silicon includes a surface deposit of silver, - separating the etched silicon from the spent etching solution, - dissolving the silver from the etched silicon using nitric acid to form a solution containing Ag+ ions and nitrate ions, - mixing the solution containing Ag+ ions and nitrate ions with further HF to form a further etching solution, and - using the further etching solution to treat further silicon.

    Abstract translation: 本发明提供了一种用于蚀刻硅以形成柱的方法,其可以用作锂离子电池中的阳极材料; 该方法包括将银沉积在硅上作为蚀刻步骤的一部分。 蚀刻的硅颗粒如图1所示。硅蚀刻后存在的银可以用硝酸处理除去。 这种去除的银可以被回收,从而降低整个过程的成本。 在一个实施方案中,该方法包括: - 处理硅,例如 颗粒或块状材料,其中包含HF,Ag +离子和硝酸根离子的蚀刻溶液,从而蚀刻硅以在其表面上形成具有蚀刻柱的硅; 硅包括银的表面沉积物, - 将蚀刻的硅与废蚀刻溶液分离, - 使用硝酸溶解来自蚀刻硅的银,以形成含有Ag +离子和硝酸根离子的溶液, - 将含有Ag +离子和 硝酸根离子与另外的HF形成另外的蚀刻溶液,并且 - 使用另外的蚀刻溶液来处理另外的硅。

    A METHOD OF FABRICATING STRUCTURED PARTICLES COMPOSED OF SILICON OR A SILICON-BASED MATERIAL AND THEIR USE IN LITHIUM RECHARGEABLE BATTERIES
    7.
    发明申请
    A METHOD OF FABRICATING STRUCTURED PARTICLES COMPOSED OF SILICON OR A SILICON-BASED MATERIAL AND THEIR USE IN LITHIUM RECHARGEABLE BATTERIES 审中-公开
    制备由硅或基于硅的材料组成的结构化颗粒的方法及其在锂可充电电池中的使用方法

    公开(公告)号:WO2010040985A1

    公开(公告)日:2010-04-15

    申请号:PCT/GB2009/002348

    申请日:2009-10-02

    Abstract: The present invention provides a process for etching silicon to form pillarsy, especially for use as the active anode material in Li-ion batteries, the process is simple to operate on a commercial scale since it uses an etching bath containing only a small number of ingredients whose concentration needs to be controlled and it can be cheaper to operate than previous processes. The etching solution comprising: 5 to 10M, e.g. 6 to 8M HF 0.01 to 0.1M Ag + ions 0.02 to 0.2M NO 3 - ions, and optionally SiF 6 2- ions alkali metal or ammonium ions, and incidental additions and impurities Further NO 3 - ions, e.g. in the form of an alkali metal or ammonium nitrate salt, are added during the etching process to maintain the concentration of nitrate ions within the above range.

    Abstract translation: 本发明提供了一种用于蚀刻硅以形成柱状的方法,特别是用作锂离子电池中的活性阳极材料,该工艺在商业规模上操作简单,因为它使用仅含有少量成分的蚀刻浴 其集中度需要被控制,并且可以比以前的过程更便宜。 该蚀刻溶液包括:5至10M,例如 6至8M HF 0.01至0.1M Ag +离子0.02至0.2M NO 3 - 离子,以及任选的SiF 6 2-离子碱金属或铵离子,以及偶然添加和杂质。 在蚀刻过程中加入碱金属或硝酸铵盐的形式,以保持硝酸根离子的浓度在上述范围内。

    METHODS AND COMPOSITIONS COMPRISING CRYSTALLINE NANOPARTICLES OF HYDROPHOBIC COMPOUNDS
    8.
    发明申请
    METHODS AND COMPOSITIONS COMPRISING CRYSTALLINE NANOPARTICLES OF HYDROPHOBIC COMPOUNDS 审中-公开
    包含疏水化合物的晶体纳米颗粒的方法和组合物

    公开(公告)号:WO2010009075A1

    公开(公告)日:2010-01-21

    申请号:PCT/US2009/050463

    申请日:2009-07-14

    CPC classification number: A61K9/145 A61K9/19 A61K31/00 A61K31/337 A61K31/4745

    Abstract: Provided herein are methods for producing crystalline nanoparticles of hydrophobic drugs, having adsorbed on the surface thereof surface stabilizers and stable dispersions comprising the same. Also provided herein are crystalline nanoparticles comprising crystalline hydrophobic compounds having adsorbed on the surface thereof surface stabilizers and stable dispersions comprising the same. The crystalline nanoparticles have a relatively low percentage of surface stabilizers by weight. Further, methods for treating a disease or unwanted condition, such as a cancer, in a subject by administering the crystalline nanoparticles of hydrophobic drugs or dispersions thereof are provided.

    Abstract translation: 本文提供了用于生产疏水性药物的结晶纳米颗粒的方法,其吸附在其表面上的表面稳定剂和包含其的稳定分散体。 本文还提供了包含在其表面上吸附有表面稳定剂的结晶疏水化合物和包含其的稳定分散体的结晶纳米颗粒。 结晶纳米颗粒的重量百分比相对较低的表面稳定剂。 此外,提供了通过施用疏水性药物或其分散体的结晶纳米颗粒来治疗受试者中疾病或不需要的疾病如癌症的方法。

    PRESERVING SECONDARY PEPTIDE STRUCTURE
    9.
    发明申请
    PRESERVING SECONDARY PEPTIDE STRUCTURE 审中-公开
    保留次级结构

    公开(公告)号:WO2009009552A3

    公开(公告)日:2009-03-12

    申请号:PCT/US2008069456

    申请日:2008-07-09

    CPC classification number: A61K47/34 A61K9/19 A61K47/26

    Abstract: A method of preserving the a-helix secondary structure of N-Acetyl-D-Asp-D-Trp-D-Phe-D-Lys-D-Ala-D-Phe-D-Tyr-D-Asp-D-Lys-D-Val-D-Ala-D-Glu-D-Lys-D-Phe-D-Lys-D-Glu-D-Ala-D-Phe-Amide or N-Acetyl-L-Asp-L-Trp-L-Phe-L-Lys-L-Ala-L-Phe-L-Tyr-L-Asp-L-Lys-L-Val-L-Ala-L-Glu-L-Lys-L-Phe-L-Lys-L-Glu-L-Ala-L-Phe-Amide and compositions comprising such peptides are disclosed.

    Abstract translation: 一种维持N-乙酰基-D-Asp-D-Trp-D-Phe-D-Lys-D-Ala-D-Phe-D-Tyr-D-Asp-D-Lys的α-螺旋二级结构的方法 -D-Val-D-Ala-D-Glu-D-Lys-D-Phe-D-Lys-D-Glu-D-Ala-D-Phe-酰胺或N-乙酰基-L-Asp-L-Trp -L-PHE-L-的Lys-L-ALA-L-的Phe-L-Tyr-L-ASP-L-的Lys-L-VAL-L-ALA-L-GLU-L-的Lys-L-PHE-L -Lys-L-Glu-L-Ala-L-Phe-Amide和包含这些肽的组合物。

    GRAPHITE-BASED PHOTOVOLTAIC CELLS
    10.
    发明申请

    公开(公告)号:WO2008112639A3

    公开(公告)日:2008-09-18

    申请号:PCT/US2008/056420

    申请日:2008-03-10

    Abstract: The present invention uses lithographically patterned graphite stacks as the basic building elements of an efficient and economical photovoltaic cell. The basic design of the graphite-based photovoltaic cells includes a plurality of spatially separated graphite stacks, each comprising a plurality of vertically stacked, semiconducting graphene sheets (carbon nanoribbons) bridging electrically conductive contacts, and forming a Schottky contact with one of said electrically conductive contacts.

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