公开(公告)号：WO2011041937A1

公开(公告)日：2011-04-14

申请号：PCT/CN2010/001550

申请日：2010-10-08

Applicant: DSM IP Assets, B.V. ,  Liu, Jiankang ,  Wang-Schmidt, Ying ,  Wertz, Karin ,  Feng, Zhihui

Inventor： Liu, Jiankang ,  Wang-Schmidt, Ying ,  Wertz, Karin ,  Feng, Zhihui

IPC: A61K31/05 ,  A61P21/02

CPC classification number: A61K31/05 ,  A23L2/52 ,  A23L33/105 ,  A61K36/63

Abstract: The use of hydroxytyrosol or an olive juice extract containing hydroxytyrosol for improving muscle differentiation and thus improving or maintaining the body's adaptation to exercise is disclosed. The pharmaceutical and nutraceutical compositions comprising hydroxytyrosol useful for conditions characterized by altered muscle differentiation especially under inflammatory conditions, such as delayed onset muscle soreness subsequent to strenuous exercise or sarcopenia are provided.

Abstract translation: 公开了使用羟基酪醇或含有羟基酪醇的橄榄汁提取物来改善肌肉分化，从而改善或维持身体适应运动。 提供了包含羟基酪醇的药物和营养组合物，其用于特征在于肌炎分化改变的病症，特别是在炎症状态下，例如剧烈运动或肌肉减少症后延迟发作的肌肉酸痛。

公开(公告)号：WO2009144093A1

公开(公告)日：2009-12-03

申请号：PCT/EP2009/054585

申请日：2009-04-17

Applicant: DSM IP Assets B.V. ,  LIU, Jiankang ,  RAEDERSTORFF, Daniel ,  WANG-SCHMIDT, Ying ,  WERTZ, Karin

Inventor： LIU, Jiankang ,  RAEDERSTORFF, Daniel ,  WANG-SCHMIDT, Ying ,  WERTZ, Karin

IPC: A61K31/05 ,  A61K36/63 ,  A61P1/16 ,  A61P7/00 ,  A61P9/00 ,  A61P21/00 ,  A23L1/00

CPC classification number: A61K31/05 ,  A61K36/63

Abstract: Hydroxytyrosol or olive juice containing hydroxytyrosol can be used to maintain or increase mitochondrial biogenesis in cardiac muscle, skeletal muscles, and liver tissue.

Abstract translation: 含有羟基酪醇的羟基酪醇或橄榄汁可用于维持或增加心肌，骨骼肌和肝组织中的线粒体生物发生。

公开(公告)号：WO2009144093A8

公开(公告)日：2011-01-06

申请号：PCT/EP2009054585

申请日：2009-04-17

Applicant: DSM IP ASSETS BV ,  LIU JIANKANG ,  RAEDERSTORFF DANIEL ,  WANG-SCHMIDT YING ,  WERTZ KARIN

Inventor： LIU JIANKANG ,  RAEDERSTORFF DANIEL ,  WANG-SCHMIDT YING ,  WERTZ KARIN

IPC: A61K31/05 ,  A23L1/00 ,  A61K36/63 ,  A61P1/16 ,  A61P7/00 ,  A61P9/00 ,  A61P21/00

CPC classification number: A61K31/05 ,  A61K36/63

Abstract: Hydroxytyrosol or olive juice containing hydroxytyrosol can be used to maintain or increase mitochondrial biogenesis in cardiac muscle, skeletal muscles, and liver tissue.

Abstract translation: 含有羟基酪醇的羟基酪醇或橄榄汁可用于维持或增加心肌，骨骼肌和肝组织中的线粒体生物发生。

公开(公告)号：WO2008128552A1

公开(公告)日：2008-10-30

申请号：PCT/EP2007/003405

申请日：2007-04-18

Applicant: DSM IP ASSETS B.V. ,  LIU, Jiankang ,  SCHALCH, Wolfgang ,  WANG-SCHMIDT, Ying ,  WERTZ, Karin

Inventor： LIU, Jiankang ,  SCHALCH, Wolfgang ,  WANG-SCHMIDT, Ying ,  WERTZ, Karin

IPC: A61K31/05

CPC classification number: A61K31/05 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/30 ,  A23V2250/2132

Abstract: The present invention is directed to the use of (a composition comprising) hydroxytyrosol for treating or preventing age-related macular degeneration in humans, for maintaining the eye health in animals (preferably in humans), especially in elderly animals (preferably elderly humans), for improving the vision of animals (preferably of humans), for maintaining the high resolution vision in animals (preferably in humans) and/or for maintaining the visual acuity in animals (preferably in humans), as well as for maintaining the visual performance in animals (preferably in humans) and/or the visual function in animals (preferably in humans).

Abstract translation: 本发明涉及用于治疗或预防人类年龄相关性黄斑变性的（含有羟基酪氨酸的组合物）用于维持动物（优选人）中的眼睛健康的用途，特别是在老年动物（优选老年人）中， 为了维持动物（优选人类）中的高分辨率视觉和/或维持动物（优选人类）中的视力，以及维持动物（优选人类）的视力，以及维持动物 动物（优选人）和/或动物（优选人类）中的视觉功能。