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公开(公告)号：WO2007146965A2
公开(公告)日：2007-12-21
申请号：PCT/US2007071049
申请日：2007-06-12
Applicant: ANACOR PHARMACEUTICALS INC , SANDERS VIRGINIA , MAPLES KIRK R , PLATTNER JACOB J , BELLINGER-KAWAHARA CAROLYN
Inventor： SANDERS VIRGINIA , MAPLES KIRK R , PLATTNER JACOB J , BELLINGER-KAWAHARA CAROLYN
Abstract: Compounds, compositions and methods are provided which are useful in the treatment of periodontal disease.
Abstract translation: 提供了可用于治疗牙周病的化合物，组合物和方法。
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公开(公告)号：WO2007095638A3
公开(公告)日：2007-08-23
申请号：PCT/US2007/062350
申请日：2007-02-16
Applicant: ANACOR PHARMACEUTICALS, INC. , BAKER, Stephen, J. , SANDERS, Virginia , AKAMA, Tsutomu , BELLINGER-KAWAHARA, Carolyn , FREUND, Yvonne , MAPLES, Kirk, R. , PLATTNER, Jacob, J. , ZHANG, Yong-Kang , ZHOU, Huchen , HERNANDEZ, Vincent, S.
Inventor： BAKER, Stephen, J. , SANDERS, Virginia , AKAMA, Tsutomu , BELLINGER-KAWAHARA, Carolyn , FREUND, Yvonne , MAPLES, Kirk, R. , PLATTNER, Jacob, J. , ZHANG, Yong-Kang , ZHOU, Huchen , HERNANDEZ, Vincent, S.
Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
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公开(公告)号：WO2006089067A2
公开(公告)日：2006-08-24
申请号：PCT/US2006/005542
申请日：2006-02-16
Applicant: ANACOR PHARMACEUTICALS, INC. , BAKER, Stephen, J. , AKAMA, Tsutomu , BELLINGER-KAWAHARA, Carolyn , HERNANDEZ, Vincent, S. , HOLD, Karin, M. , LEYDEN, James, J. , MAPLES, Kirk, R. , PLATTNER, Jacob, J. , SANDERS, Virginia , ZHANG, Yong-Kang
Inventor： BAKER, Stephen, J. , AKAMA, Tsutomu , BELLINGER-KAWAHARA, Carolyn , HERNANDEZ, Vincent, S. , HOLD, Karin, M. , LEYDEN, James, J. , MAPLES, Kirk, R. , PLATTNER, Jacob, J. , SANDERS, Virginia , ZHANG, Yong-Kang
CPC classification number: C07F5/025 , A61K9/0012 , A61K31/69 , C07F5/02 , C07F5/027
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Abstract translation: 本发明涉及可用于治疗真菌感染的化合物，更具体地涉及甲真菌病和/或皮肤真菌感染的局部治疗。 本发明涉及对真菌具有活性的化合物，并且具有允许化合物与患者接触时达到感染真菌的皮肤，指甲，头发，爪或蹄特定部位的性质。 特别地，本发明化合物具有促进钉板穿透的物理化学性质。
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公开(公告)号：WO2006085932A2
公开(公告)日：2006-08-17
申请号：PCT/US2005020978
申请日：2005-06-14
Applicant: ANACOR PHARMACEUTICALS INC , BELLINGER-KAWAHARA CAROLYN , MAPLES KIRK R , PLATTNER JACOB J
Inventor： BELLINGER-KAWAHARA CAROLYN , MAPLES KIRK R , PLATTNER JACOB J
CPC classification number: A61K31/69
Abstract: Compostions and methods of use of boronic acid complexes, especially hydroxyquinoline, imidazole and picolinic acid derivatives, as anti-viral agents as well as therapeutic agents for the treatment of diseases caused by viruses are described.
Abstract translation: 描述了使用硼酸络合物，特别是羟基喹啉，咪唑和吡啶甲酸衍生物作为抗病毒剂的组合物和方法以及用于治疗由病毒引起的疾病的治疗剂。
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公开(公告)号：WO2006007384B1
公开(公告)日：2006-08-17
申请号：PCT/US2005021214
申请日：2005-06-14
Applicant: ANACOR PHARMACEUTICALS INC , LEE VING , BENKOVIC STEPHEN J , BAKER STEPHEN J , MAPLES KIRK R , AKAMA TSUTOMU , ZHANG YONG-KANG , SINGH RAJESHWAR , SAURO VITTORIO A , PANDIT CHETAN , SU ZHUOYI , YANG ZHIXIANG
Inventor： LEE VING , BENKOVIC STEPHEN J , BAKER STEPHEN J , MAPLES KIRK R , AKAMA TSUTOMU , ZHANG YONG-KANG , SINGH RAJESHWAR , SAURO VITTORIO A , PANDIT CHETAN , SU ZHUOYI , YANG ZHIXIANG
CPC classification number: C07F5/025
Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
Abstract translation: 公开了掺入硼酸配合物的抗生素的结构和制备方法，特别是羟基喹啉，咪唑和吡啶甲酸衍生物，以及这些抗生素的组合物以及使用该抗生素和组合物作为杀菌剂和杀真菌剂以及治疗剂用于治疗 由细菌和真菌引起的疾病。
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Patent Agency Ranking
公开(公告)号：WO2006007384A3
公开(公告)日：2006-04-06
申请号：PCT/US2005021214
申请日：2005-06-14
Applicant: ANACOR PHARMACEUTICALS INC , LEE VING , BENKOVIC STEPHEN J , BAKER STEPHEN J , MAPLES KIRK R , AKAMA TSUTOMU , ZHANG YONG-KANG , SINGH RAJESHWAR , SAURO VITTORIO A , PANDIT CHETAN , SU ZHUOYI , YANG ZHIXIANG
Inventor： LEE VING , BENKOVIC STEPHEN J , BAKER STEPHEN J , MAPLES KIRK R , AKAMA TSUTOMU , ZHANG YONG-KANG , SINGH RAJESHWAR , SAURO VITTORIO A , PANDIT CHETAN , SU ZHUOYI , YANG ZHIXIANG
CPC classification number: C07F5/025
Abstract: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
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7.发明申请
公开(公告)号：WO2007131072A3
公开(公告)日：2008-07-03
申请号：PCT/US2007068079
申请日：2007-05-02
Applicant: ANACOR PHARMACEUTICALS INC , LEE VING , PLATTNER JACOB J , BENKOVIC STEPHEN J , BAKER STEPHEN J , MAPLES KIRK R , BELLINGER-KAWAHARA CAROLYN , AKAMA TSUTOMU , ZHANG YONG-KANG , SINGH RAJESHWAR , SAURO VITTORIO A
Inventor： LEE VING , PLATTNER JACOB J , BENKOVIC STEPHEN J , BAKER STEPHEN J , MAPLES KIRK R , BELLINGER-KAWAHARA CAROLYN , AKAMA TSUTOMU , ZHANG YONG-KANG , SINGH RAJESHWAR , SAURO VITTORIO A
IPC: C07D305/00
CPC classification number: C07F5/025
Abstract: Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
Abstract translation: 公开了用于治疗由真菌，酵母，细菌或病毒引起的疾病的治疗剂的硼衍生物，包括苯并恶唑，苯并唑并苯并噻唑的组合物和方法，以及合成所述试剂及其组合物的方法。
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公开(公告)号：WO2006089067A3
公开(公告)日：2007-07-19
申请号：PCT/US2006005542
申请日：2006-02-16
Applicant: ANACOR PHARMACEUTICALS INC , BAKER STEPHEN J , AKAMA TSUTOMU , BELLINGER-KAWAHARA CAROLYN , HERNANDEZ VINCENT S , HOLD KARIN M , LEYDEN JAMES J , MAPLES KIRK R , PLATTNER JACOB J , SANDERS VIRGINIA , ZHANG YONG-KANG
Inventor： BAKER STEPHEN J , AKAMA TSUTOMU , BELLINGER-KAWAHARA CAROLYN , HERNANDEZ VINCENT S , HOLD KARIN M , LEYDEN JAMES J , MAPLES KIRK R , PLATTNER JACOB J , SANDERS VIRGINIA , ZHANG YONG-KANG
IPC: A61K31/343 , C07D307/77
CPC classification number: C07F5/025 , A61K9/0012 , A61K31/69 , C07F5/02 , C07F5/027
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Abstract translation: 本发明涉及可用于治疗真菌感染的化合物，更具体地涉及甲真菌病和/或皮肤真菌感染的局部治疗。 本发明涉及对真菌具有活性的化合物，并且具有允许化合物与患者接触时达到感染真菌的皮肤，指甲，毛发，爪或蹄特定部位的性质。 特别地，本发明化合物具有促进钉板穿透的物理化学性质。
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9.发明申请
公开(公告)号：WO2005123094A3
公开(公告)日：2005-12-29
申请号：PCT/US2005/021165
申请日：2005-06-14
Applicant: ANACOR PHARMACEUTICALS, INC. , PERRY, David , MAPLES, Kirk, R. , BELLINGER-KAWAHARA, Carolyn
Inventor： PERRY, David , MAPLES, Kirk, R. , BELLINGER-KAWAHARA, Carolyn
IPC: A61K31/69
Abstract: Methods of treating and/or preventing surface infections, such as acne, in an animal, such as a human being, using antibiotics incorporating borinic acid complexes, especially picolinic acid derivatives, are disclosed, along with compositions of these antibiotics.
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公开(公告)号：WO1998003496A1
公开(公告)日：1998-01-29
申请号：PCT/US1997011960
申请日：1997-07-14
Applicant: CENTAUR PHARMACEUTICALS, INC. , KELLEHER, Judith, A. , MAPLES, Kirk, R. , WATERBURY, Lowell, David , WILCOX, Allan, L. , XU, Hong , ZHANG, Yong-Kang
Inventor： CENTAUR PHARMACEUTICALS, INC.
IPC: C07D307/64
CPC classification number: A61K31/341 , C07D307/64
Abstract: Disclosed are furan nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compounds are useful as analytical reagents for detecting free radicals and as therapeutics for treating a wide variety of medical dysfunctions and diseases.
Abstract translation: 公开了呋喃硝酮化合物和含有这些化合物的药物组合物。 所公开的化合物可用作检测自由基的分析试剂和用作治疗各种各样的医学功能障碍和疾病的治疗剂。
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