公开(公告)号：WO1997031620A2

公开(公告)日：1997-09-04

申请号：PCT/US1997003169

申请日：1997-02-28

Applicant: JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. ,  LIU, Jue-Chen ,  WANG, Jonas, C., T. ,  YUSUF, Mohammed ,  YAMAMOTO, Norihiro ,  KAZAMA, Satoshi ,  STAHL, Christopher, R. ,  MATHER, Kamran ,  HOLLAND, Jean, P. ,  ALELES, Margaret, A. ,  HAMADA, Sachio ,  COLE, Curtis, A. ,  WISNIEWSKI, Stephen, J.

Inventor： JOHNSON & JOHNSON CONSUMER PRODUCTS, INC.

IPC: A61K07/48

CPC classification number: A61K8/06 ,  A61K8/062 ,  A61K8/671 ,  A61K2800/51 ,  A61K2800/522 ,  A61K2800/75 ,  A61K2800/88 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  Y10S514/844 ,  Y10S514/847 ,  Y10S514/887 ,  Y10S514/938 ,  Y10S514/941

Abstract: Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability, comprising a stabilizing system selected from the group consisting of: a) at least one oil-soluble antioxydant; b) a chelating agent and at least one oil-soluble antioxydant; c) a chelating agent; and d) a chelating agent and an antioxydant present in each of the oil and water phases of said emulsion.

Abstract translation: 包含含有类视黄醇并具有良好物理和化学稳定性的水包油乳液基质的皮肤护理组合物，其包含选自以下的稳定体系：a）至少一种油溶性抗氧化剂; b）螯合剂和至少一种油溶性抗氧化剂; c）螯合剂; 和d）存在于所述乳液的每个油相和水相中的螯合剂和抗氧化剂。

公开(公告)号：WO9731620A3

公开(公告)日：1998-01-08

申请号：PCT/US9703169

申请日：1997-02-28

Applicant: JOHNSON & JOHNSON CONSUMER ,  LIU JUE CHEN ,  WANG JONAS C T ,  YUSUF MOHAMMED ,  YAMAMOTO NORIHIRO ,  KAZAMA SATOSHI ,  STAHL CHRISTOPHER R ,  MATHER KAMRAN ,  HOLLAND JEAN P ,  ALELES MARGARET A ,  HAMADA SACHIO ,  COLE CURTIS A ,  WISNIEWSKI STEPHEN J

Inventor： LIU JUE-CHEN ,  WANG JONAS C T ,  YUSUF MOHAMMED ,  YAMAMOTO NORIHIRO ,  KAZAMA SATOSHI ,  STAHL CHRISTOPHER R ,  MATHER KAMRAN ,  HOLLAND JEAN P ,  ALELES MARGARET A ,  HAMADA SACHIO ,  COLE CURTIS A ,  WISNIEWSKI STEPHEN J

IPC: A45D34/00 ,  A61K20060101 ,  A61K8/00 ,  A61K8/06 ,  A61K8/30 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/60 ,  A61K8/67 ,  A61K8/92 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  B32B15/08 ,  B65D65/40 ,  A61K7/48

CPC classification number: A61K8/06 ,  A61K8/062 ,  A61K8/671 ,  A61K2800/51 ,  A61K2800/522 ,  A61K2800/75 ,  A61K2800/88 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  Y10S514/844 ,  Y10S514/847 ,  Y10S514/887 ,  Y10S514/938 ,  Y10S514/941

Abstract: Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability, comprising a stabilizing system selected from the group consisting of: a) at least one oil-soluble antioxydant; b) a chelating agent and at least one oil-soluble antioxydant; c) a chelating agent; and d) a chelating agent and an antioxydant present in each of the oil and water phases of said emulsion.

公开(公告)号：WO1996039119A1

公开(公告)日：1996-12-12

申请号：PCT/US1996009545

申请日：1996-06-05

Applicant: NEUTROGENA CORPORATION ,  MATHER, Kamran ,  STAHL, Christopher, Ryan

Inventor： NEUTROGENA CORPORATION

IPC: A61K07/48

CPC classification number: A61K8/362 ,  A61K8/345 ,  A61K8/8158 ,  A61Q19/00 ,  Y10S514/859

Abstract: A completely solubilized topical composition of azelaic acid in a glycol base which is stable at normal temperatures and pressures and which is useful as a commercial substitute for dispersed azelaic acid preparations.

Abstract translation: 乙二醇碱中完全溶解的壬二酸的局部组合物，其在常温常压下是稳定的，可用作分散的壬二酸制剂的商业替代物。