USE OF ZERUMBONE FOR A COSMETIC TREATMENT
    6.
    发明申请

    公开(公告)号:WO2022268643A1

    公开(公告)日:2022-12-29

    申请号:PCT/EP2022/066480

    申请日:2022-06-16

    申请人: SEDERMA

    摘要: According to the invention, zerumbone, derivative and/or analog thereof, or of a plant extract containing it, is used for a treatment of hyperpigmented areas on the skin (to prevent them from appearing and/or to treat them once they are present so that they fade and/or disappear), through the phosphorylation of Akt, ERK-1 and ERK-2 metabolic pathways, and the reduction of PGE2 production, influencing the tyrosinase and melanin production, therefore its transfer from the melanosome to the keratinocytes. The zerumbone or the plant extract containing it is from the Zingiberaceae family and the extraction is carried out using a supercritical fluid.

    AN ELASTOMERIC ARTICLE
    8.
    发明申请

    公开(公告)号:WO2022216148A1

    公开(公告)日:2022-10-13

    申请号:PCT/MY2021/050047

    申请日:2021-06-16

    摘要: The present invention relates to an elastomeric article (10) and a method of making thereof. The elastomeric article (10) comprising a substrate body (11) defining an inner surface (12) proximal to skin of a user and an outer surface (13) distal to the skin of the user, the substrate body (11) comprises an elastomer; an intermediate coating (15) overlying at least a portion of the inner surface (12), the intermediate coating (15) comprises a therapeutic agent; and an inner coating (14) overlying at least a portion of the intermediate coating (15), wherein the inner coating (14) comprises an extract of soapnuts for preserving the therapeutic agent.