公开(公告)号：WO1995019141A2

公开(公告)日：1995-07-20

申请号：PCT/US1995000452

申请日：1995-01-12

Applicant: McGUIRE, David, A.

IPC: A61B17/16

CPC classification number: A61F2/0805 ,  A61B17/1637 ,  A61B17/1659 ,  A61B17/1675 ,  A61B17/1714 ,  A61B17/1764 ,  A61B17/1796

Abstract: A bone-cutting guide having a base with a cylindrical tunnel for guiding a cutting instrument therethrough. The guide is anchored to the bone in at least three locations. A positioning arm having a distal end anchors the guide within a joint. An anchoring pin is insertable through the base alongside the cylindrical tunnel to stabilize the guide against the bone being drilled. An embodiment of the invention includes two anchoring pins on either side of the cylindrical tunnel through the base. The positioning arm can be stabilized within a joint due the stabilizing spikes extending from the distal end of the arm. A curve is provided in the positioning arm between two spikes to provide an opening through which a reamer guided through the cylindrical tunnel may be operated.

Abstract translation: 一种骨切割引导件，具有带圆柱形通道的基座，用于引导切割器械通过。 指南至少在三个位置固定在骨骼上。 具有远端的定位臂将引导件固定在接头内。 锚定销可以沿着圆柱形隧道穿过基座，以将引导件抵靠被钻的骨头稳定。 本发明的一个实施例包括通过基座的圆柱形隧道两侧的两个锚定销。 由于从臂的远端延伸的稳定尖峰，定位臂可以在接头内稳定。 在两个钉之间的定位臂中提供曲线，以提供一个开口，通过圆柱形通道引导的铰刀可通过该开口操作。

公开(公告)号：WO2012139020A1

公开(公告)日：2012-10-11

申请号：PCT/US2012/032554

申请日：2012-04-06

Applicant: STOKES BIO LIMITED ,  AGUANNO, Mauro ,  BARRETT, Brian ,  CHAWKE, Brian ,  CURRAN, Kieran ,  CURTIN, Damian ,  DALTON, Tara ,  DAVIES, Mark ,  HOU, Xiaona ,  KINAHAN, David ,  KING, Damien ,  KORENKE, Mark ,  MCCARTHY, Conor ,  MCGUIRE, David ,  SAYERS, Michael ,  SIRR, Noel ,  TALBOT, Ryan

Inventor： AGUANNO, Mauro ,  BARRETT, Brian ,  CHAWKE, Brian ,  CURRAN, Kieran ,  CURTIN, Damian ,  DALTON, Tara ,  DAVIES, Mark ,  HOU, Xiaona ,  KINAHAN, David ,  KING, Damien ,  KORENKE, Mark ,  MCCARTHY, Conor ,  MCGUIRE, David ,  SAYERS, Michael ,  SIRR, Noel ,  TALBOT, Ryan

IPC: B01L3/00 ,  B01F13/00 ,  B01F15/00

CPC classification number: C12Q1/686 ,  B01F13/0005 ,  B01F13/0071 ,  B01F15/00214 ,  B01L3/502715 ,  B01L3/502784 ,  B01L7/52 ,  B01L7/525 ,  B01L2200/143 ,  B01L2300/06 ,  B01L2300/0654 ,  B01L2300/0867 ,  G01N21/6428 ,  G01N35/00623 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2035/00465 ,  G01N2201/062

Abstract: Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.

Abstract translation: 本文提供了一种生物检测系统和使用方法，其中生物检测系统包括用于组合至少两个液滴的至少一个混合器或液体桥和用于检测是否适当混合或组合两个组分液滴的误差校正系统 已经发生

公开(公告)号：WO2004058076A3

公开(公告)日：2004-07-15

申请号：PCT/US2003/040381

申请日：2003-12-18

Applicant: SMITH & NEPHEW, INC. ,  MCGUIRE, David, A. ,  TORRIE, Paul (Alec)

Inventor： MCGUIRE, David, A. ,  TORRIE, Paul (Alec)

IPC: A61B17/32

Abstract: A surgical punch including an upper jaw and lower jaw that are coupled at their proximal ends. The jaws have cutting edges at their distal end configured to cut in a direction from the distal ends of the jaws towards the proximal ends of the jaws. The center of rotation of the cutting trajectory can be located above the initial cutting point of the lower jaw. The upper jaw can include a reversed slope leading edge. The jaws can be slidably coupled to each other. The coupling member can include a pin and slot to couple the movable jaw to an actuating rod.

公开(公告)号：WO9519141A3

公开(公告)日：1995-08-31

申请号：PCT/US9500452

申请日：1995-01-12

Applicant: MCGUIRE DAVID A

Inventor： MCGUIRE DAVID A

IPC: A61B17/16 ,  A61B17/17 ,  A61F2/08

CPC classification number: A61F2/0805 ,  A61B17/1637 ,  A61B17/1659 ,  A61B17/1675 ,  A61B17/1714 ,  A61B17/1764 ,  A61B17/1796

Abstract: A bone-cutting guide having a base with a cylindrical tunnel for guiding a cutting instrument therethrough. The guide is anchored to the bone in at least three locations. A positioning arm having a distal end anchors the guide within a joint. An anchoring pin is insertable through the base alongside the cylindrical tunnel to stabilize the guide against the bone being drilled. An embodiment of the invention includes two anchoring pins on either side of the cylindrical tunnel through the base. The positioning arm can be stabilized within a joint due the stabilizing spikes extending from the distal end of the arm. A curve is provided in the positioning arm between two spikes to provide an opening through which a reamer guided through the cylindrical tunnel may be operated.

公开(公告)号：WO2012139041A1

公开(公告)日：2012-10-11

申请号：PCT/US2012/032590

申请日：2012-04-06

Applicant: STOKES BIO LIMITED ,  CHAWKE, Brian ,  CURRAN, Kieran ,  MCGUIRE, David ,  SAYERS, Michael ,  SIRR, Noel

Inventor： CHAWKE, Brian ,  CURRAN, Kieran ,  MCGUIRE, David ,  SAYERS, Michael ,  SIRR, Noel

IPC: B01L3/00 ,  G01N1/28

CPC classification number: B01L3/50273 ,  B01F13/0071 ,  B01F13/0076 ,  B01J19/087 ,  B01L3/502715 ,  B01L3/502784 ,  B01L3/52 ,  B01L3/56 ,  B01L2200/0673 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0415 ,  B05B5/035 ,  C12Q1/686 ,  G01N1/38 ,  G01N2001/4038

Abstract: Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic sysems. The charging is performed by producing an ion field(50) between an ionizing electrode(20) and an opposed ground electrode(30). A fluid-containing vessel(40) is positioned between the opposedelectrodes and the ion field charges the fluid(41) in the vessel.

Abstract translation: 公开了用于充液的装置，系统和方法。 流体充液改善了微流体系统中流体的混合。 通过在电离电极（20）和相对的接地电极（30）之间产生离子场（50）来进行充电。 含有流体的容器（40）位于相对的电极之间，离子场对容器中的流体（41）充电。

公开(公告)号：WO0042538A3

公开(公告)日：2001-02-01

申请号：PCT/GB0000092

申请日：2000-01-14

Applicant: HOCHFIELD BARRY ,  MCGUIRE DAVID T ,  BRADDOCK DAVID

Inventor： HOCHFIELD BARRY ,  MCGUIRE DAVID T ,  BRADDOCK DAVID

IPC: G06Q30/00 ,  G06F17/60

CPC classification number: G06Q30/06

Abstract: A system for reallocating seats at a venue when ticket holders do not appear. The system (10) identifies a total number of pre-paid tickets (16) issued for an event, determines a number of stand-by tickets (24) from a statistical probability of pre-paid ticket holders (20) failing to arrive for the event, records sale of the stand-by tickets (24) to impromptu purchasers (26) who are directed to a stand-by lounge, records the arrival (30) at the event of each pre-paid ticket holder (20) and repeatedly determines (22) a likelihood of continued non-arrival of remaining pre-paid ticket holders (20) based on a history, if any, of their previous attendance of similar events and at a pre-determined time interval prior to commencement of the event re-allocates at least some of the impromptu purchasers (26) to the space ("seats"), of the non-arrived pre-paid ticket holders (20) who have been determined as least likely to appear while providing a TV relayed version of the event to the remaining impromptu purchasers remaining in the stand-by lounge.

Abstract translation: 一个系统，用于在不存在售票持有者时在场地重新分配座位。 系统（10）识别为事件发放的预付票（16）的总数，从预付票持有者（20）未能到达的统计概率确定待机票数（24） 记录销售待命车票（24）到即期购买者（26），他们被送往待命休息室，记录每个预付票持有人（20）的到达（30）和 反复确定（22）剩余的预付票持有人（20）继续未到达的可能性，基于他们以前参加类似事件的历史（如果有的话），并且在开始之前的预定时间间隔 事件将至少一些临时购买者（26）重新分配给未到达的预付票持有人（20）的空间（“座位”），这些已被确定为最少可能出现的提供电视转播的预付票 剩余即将到来的购买者留在待机休息室的活动版本。

公开(公告)号：WO2004058076A2

公开(公告)日：2004-07-15

申请号：PCT/US0340381

申请日：2003-12-18

Applicant: SMITH & NEPHEW INC ,  MCGUIRE DAVID A ,  TORRIE PAUL ALEC

Inventor： MCGUIRE DAVID A ,  TORRIE PAUL ALEC

IPC: A61B17/28 ,  A61B17/32 ,  A61B17/00

CPC classification number: A61B17/1608 ,  A61B17/282 ,  A61B17/320016 ,  A61B2017/2934 ,  A61B2017/2936 ,  A61B2017/2944

Abstract: A surgical punch including an upper jaw and lower jaw that are coupled at their proximal ends. The jaws have cutting edges at their distal end configured to cut in a direction from the distal ends of the jaws towards the proximal ends of the jaws. The center of rotation of the cutting trajectory can be located above the initial cutting point of the lower jaw. The upper jaw can include a reversed slope leading edge. The jaws can be slidably coupled to each other. The coupling member can include a pin and slot to couple the movable jaw to an actuating rod.

Abstract translation: 手术冲头包括在其近端联接的上颌和下颌。 钳口在其远端处具有切割边缘，该切割边缘构造成沿从钳口的远端朝向钳口的近端的方向切割。 切割轨迹的旋转中心可以位于下颚的初始切割点的上方。 上颚可以包括反斜坡前缘。 钳口可以可滑动地彼此连接。 联接构件可以包括销和槽以将活动夹爪联接到致动杆。

公开(公告)号：WO1998019610A1

公开(公告)日：1998-05-14

申请号：PCT/US1997020072

申请日：1997-11-05

Applicant: MCGUIRE, David, A.

IPC: A61B17/32

CPC classification number: A61B17/320016 ,  A61B17/00008 ,  A61B2017/00969 ,  A61B2090/08021

Abstract: A device for harvesting a tendon for cruciate ligament surgery includes an elongated outer member and an inner member disposed within the outer member, such that the outer and inner members are reciprocally movable relative to one another. The outer member has, at its distal end, a cutting edge for cutting connective tissues about the periphery of the tendon. The inner member is provided with a distal end and pathway into which the tendon is received during the harvesting procedure. The device further includes an actuator for moving the outer member and inner member between a non-actuated positoin, wherein the distal end of the outer member and the distal end of the inner member are at least in substantially even alignment, and an actuated position, wherein the distal end of the outer member is advanced beyond the distal end of the inner member, so as to expose the cutting edge for separating connective tissues about the periphery of the tendon.

Abstract translation: 用于收获十字韧带手术的腱的装置包括细长的外部构件和设置在外部构件内部的内部构件，使得外部构件和内部构件可相对于彼此往复运动。 外部构件在其远端处具有用于切割围绕腱周边的结缔组织的切割边缘。 内部构件设置有在收割过程中腱被接收到其中的远端和通路。 该装置还包括用于在非致动的定位位置之间移动外部构件和内部构件的致动器，其中外部构件的远端和内部构件的远端至少基本上均匀对准，以及致动位置， 其中所述外部构件的远端超出所述内部构件的远端，以便暴露所述切割边缘以围绕所述腱的周边分离结缔组织。