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    COATINGS FOR CAPILLARIES CAPABLE OF CAPTURING ANALYTES
    2.
    发明申请
    COATINGS FOR CAPILLARIES CAPABLE OF CAPTURING ANALYTES 审中-公开
    可用于捕获分析的毛细管涂层

    公开(公告)号：WO2008013801A3

    公开(公告)日：2008-06-26

    申请号：PCT/US2007016626

    申请日：2007-07-23

    Applicant: CELL BIOSCIENCES INC ,  BORDUNOV ANDREI V ,  VOSS KARL O ,  CLIZBE LANE A ,  O'NEILL ROGER A

    Inventor： BORDUNOV ANDREI V ,  VOSS KARL O ,  CLIZBE LANE A ,  O'NEILL ROGER A

    IPC: C12M1/34

    CPC classification number: G01N27/44717 ,  C08F220/56 ,  G01N27/44791 ,  C08F220/54

    Abstract: In general, the present invention provides microfluidic devices comprised of polymer coatings with triggerable analyte capture moieties. In some embodiments, a microfluidic device is provided, useful in electrophoresis, and is comprised of at least one separation channel with a surface, such as but not necessarily an inner surface, and having a polymer coating introduced onto the surface. The polymer coating is comprised of moieties capable of being triggered to immobilize analytes to the surface.

    Abstract translation: 通常，本发明提供由聚合物涂层和可触发的分析物捕获部分组成的微流体装置。 在一些实施方案中，提供了微流体装置，其可用于电泳，并且包含至少一个带有表面的分离通道，例如但不一定是内表面，并具有引入表面上的聚合物涂层。 聚合物涂层由能够被触发以将分析物固定到表面的部分组成。

    COATINGS FOR CAPILLARIES CAPABLE OF CAPTURING ANALYTES
    3.
    发明申请
    COATINGS FOR CAPILLARIES CAPABLE OF CAPTURING ANALYTES 审中-公开
    用于捕捉分析物的毛毡涂层

    公开(公告)号：WO2008013801A2

    公开(公告)日：2008-01-31

    申请号：PCT/US2007/016626

    申请日：2007-07-23

    Applicant: CELL BIOSCIENCES, INC. ,  BORDUNOV, Andrei, V. ,  VOSS, Karl, O. ,  CLIZBE, Lane, A. ,  O'NEILL, Roger, A.

    Inventor： BORDUNOV, Andrei, V. ,  VOSS, Karl, O. ,  CLIZBE, Lane, A. ,  O'NEILL, Roger, A.

    IPC: C07K1/26 ,  G01N27/00

    CPC classification number: G01N27/44717 ,  C08F220/56 ,  G01N27/44791 ,  C08F220/54

    Abstract: In general, the present invention provides microfluidic devices comprised of polymer coatings with triggerable analyte capture moieties. In some embodiments, a microfluidic device is provided, useful in electrophoresis, and is comprised of at least one separation channel with a surface, such as but not necessarily an inner surface, and having a polymer coating introduced onto the surface. The polymer coating is comprised of moieties capable of being triggered to immobilize analytes to the surface.

    Abstract translation: 通常，本发明提供由具有可触发分析物捕获部分的聚合物涂层组成的微流体装置。 在一些实施方案中，提供了可用于电泳的微流体装置，并且包括至少一个具有表面的分离通道，例如但不一定是内表面，并且具有引入到表面上的聚合物涂层。 聚合物涂层由能被触发以将分析物固定在表面上的部分组成。

    AUTOMATED MICRO-VOLUME ASSAY SYSTEM
    4.
    发明申请
    AUTOMATED MICRO-VOLUME ASSAY SYSTEM 审中-公开
    自动微量测定系统

    公开(公告)号：WO2006110725A8

    公开(公告)日：2007-08-16

    申请号：PCT/US2006013447

    申请日：2006-04-10

    Applicant: CELL BIOSCIENCES INC ,  ROACH DAVID J ,  YANG TOM W ,  O'NEILL ROGER A ,  LODER JR ROBERT T ,  VANDER HORN PETER B

    Inventor： ROACH DAVID J ,  YANG TOM W ,  O'NEILL ROGER A ,  LODER JR ROBERT T ,  VANDER HORN PETER B

    IPC: A47J36/02

    CPC classification number: F16L41/00 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/1034 ,  G01N2035/1039 ,  G01N2035/1051 ,  G01N2035/1062 ,  Y10T137/0318 ,  Y10T137/85938 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/2575

    Abstract: An automated assay system is described with stations for placement of materials to be used in an assay of materials inside capillaries and an automated gripper for manipulating capillaries. The system includes a separation and immobilization station where reactions inside the capillaries take place and a detector station where photoemissions from the capillary reactions are detected. The photoemissions from the capillaries may be displayed as line graphs or in columns of a pseudo-gel image resembling the familiar Western gel blot. An automated control system has a user interface by which an operator can select a run protocol and define the locations of samples and reagents to be used in the protocol run. Following the setup the control system will cause the automated system to execute the protocol, then display the results in a selected display format.

    Abstract translation: 描述了一种自动测定系统，其中用于放置在毛细管内部的材料测定中使用的材料的工位和用于操纵毛细管的自动化夹具。 该系统包括一个分离和固定站，毛细管内发生反应，检测站检测来自毛细管反应的光电发射。 来自毛细血管的光发射可以显示为类似于熟悉的Western凝胶印迹的假凝胶图像的线图或列。 自动化控制系统具有用户界面，操作员可通过该界面选择运行方案并定义在方案运行中使用的样品和试剂的位置。 设置完成后，控制系统将使自动化系统执行协议，然后以选定的显示格式显示结果。

    PROTECTION OF HARVESTED CROPS FROM PATHOGENS BY TREATMENT WITH ENZYMES
    5.
    发明申请
    PROTECTION OF HARVESTED CROPS FROM PATHOGENS BY TREATMENT WITH ENZYMES 审中-公开
    通过用酶处理保护受病原体的病原体

    公开(公告)号：WO1991006312A1

    公开(公告)日：1991-05-16

    申请号：PCT/US1990006085

    申请日：1990-10-26

    Applicant: GENENCOR INTERNATIONAL INC. ,  ALBERSHEIM, Peter ,  BEN-YEHOSHUA, Shimshon ,  O'NEILL, Roger, A. ,  POULOSE, Ayrookaran, J.

    Inventor： GENENCOR INTERNATIONAL INC.

    IPC: A61K37/54

    CPC classification number: A23B9/28 ,  A01N63/00 ,  A23B7/155 ,  A01N61/00 ,  A01N25/30 ,  A01N2300/00

    Abstract: A method is disclosed for protecting a harvested crop from pathogens comprising applying to the harvested crop and to any pathogen present thereon a compound capable of generating an active oligomer elicitor in the crop or the pathogen. The compound is applied with a penetrating agent which aids in the entry of the compound into the cuticle layer of the harvested crop or the pathogen. The elicitor is generated in the crop or the pathogen in an amount effective to elicit production in the crop of an anti-pathogenic agent. When the elicitor is generated in a pathogen present on the harvested crop, the elicitor is generated in sufficient amount to transfer into the crop, which transfer may be aided by the presence of said penetrating agent, in order to produce the desired phytoalexins in the harvested crop. Also disclosed is a composition comprising the above compound and a penetrating agent for the compound as well as a harvested crop treated with the above composition.

    Abstract translation: 公开了一种用于保护收获的作物免受病原体的方法，包括施用于收获的作物和存在于其上的任何能够在作物或病原体中产生活性寡聚体诱发剂的化合物的病原体。 该化合物被施用有助于化合物进入收获的作物或病原体的角质层的渗透剂。 激发剂在作物或病原体中以有效引起作物中抗生素剂产生的量产生。 当引诱剂在收获的作物上存在的病原体中产生时，产生足够量的诱发子以转移到作物中，所述转移可以通过所述渗透剂的存在来辅助，以便在收获的作物中产生所需的植物抗坏血酸 作物。 还公开了包含上述化合物和化合物的渗透剂以及用上述组合物处理的收获的作物的组合物。

    PROTECTION OF GROWING CROPS FROM PATHOGENS BY TREATMENT WITH ENZYMES
    7.
    发明申请
    PROTECTION OF GROWING CROPS FROM PATHOGENS BY TREATMENT WITH ENZYMES 审中-公开
    通过用酶处理保护来自病原体的作物

    公开(公告)号：WO1991006313A1

    公开(公告)日：1991-05-16

    申请号：PCT/US1990006086

    申请日：1990-10-26

    Applicant: GENENCOR INTERNATIONAL INC. ,  KOLATTUKUDY, Pappachan, E. ,  O'NEILL, Roger, A. ,  POULOSE, Ayrookaran, J.

    Inventor： GENENCOR INTERNATIONAL INC.

    IPC: A61K37/54

    CPC classification number: A01N63/00 ,  A01N61/00 ,  A01N25/30 ,  A01N2300/00

    Abstract: A method is disclosed for protecting a growing crop from pathogens comprising applying to the growing crop and to any pathogen present thereon a compound capable of generating an active oligomer elicitor in the crop or the pathogen. The compound is applied with a penetrating agent which aids in the entry of the compound into the cuticle layer of the growing crop or the pathogen. The elicitor is generated in the crop or the pathogen in an amount effective to elicit production in the crop of an anti-pathogenic agent. When the elicitor is generated in a pathogen present on the harvested crop, the elicitor is generated in sufficient amount to transfer into the crop, which transfer may be aided by the presence of said penetrating agent, in order to produce the desired phytoalexins in the harvested crop. Also disclosed is a composition comprising the above compound and a penetrating agent for the compound as well as a growing crop treated with the above composition.

    Abstract translation: 公开了一种用于保护生长的作物免受病原体的方法，其包括施用于生长的作物和存在于其上的任何病原体上能够在作物或病原体中产生活性寡聚体诱发剂的化合物。 该化合物施用有助于化合物进入生长作物或病原体的角质层的渗透剂。 激发剂在作物或病原体中以有效引起作物中抗生素剂产生的量产生。 当引诱剂在收获的作物上存在的病原体中产生时，产生足够量的诱发子以转移到作物中，所述转移可以通过所述渗透剂的存在来辅助，以便在收获的作物中产生所需的植物抗坏血酸 作物。 还公开了包含上述化合物和用于该化合物的渗透剂以及用上述组合物处理的生长作物的组合物。

    AUTOMATED MICRO-VOLUME ASSAY SYSTEM
    9.
    发明申请
    AUTOMATED MICRO-VOLUME ASSAY SYSTEM 审中-公开
    自动微量测定系统

    公开(公告)号：WO2006110725A3

    公开(公告)日：2007-11-22

    申请号：PCT/US2006013447

    申请日：2006-04-10

    Applicant: CELL BIOSCIENCES INC ,  ROACH DAVID J ,  YANG TOM W ,  O'NEILL ROGER A ,  LODER JR ROBERT T ,  VANDER HORN PETER B

    Inventor： ROACH DAVID J ,  YANG TOM W ,  O'NEILL ROGER A ,  LODER JR ROBERT T ,  VANDER HORN PETER B

    IPC: G01N35/00

    CPC classification number: F16L41/00 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/1034 ,  G01N2035/1039 ,  G01N2035/1051 ,  G01N2035/1062 ,  Y10T137/0318 ,  Y10T137/85938 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/2575

    Abstract: An automated assay system is described with stations for placement of materials to be used in an assay of materials inside capillaries and an automated gripper for manipulating capillaries. The system includes a separation and immobilization station where reactions inside the capillaries take place and a detector station where photoemissions from the capillary reactions are detected. The photoemissions from the capillaries may be displayed as line graphs or in columns of a pseudo-gel image resembling the familiar Western gel blot. An automated control system has a user interface by which an operator can select a run protocol and define the locations of samples and reagents to be used in the protocol run. Following the setup the control system will cause the automated system to execute the protocol, then display the results in a selected display format.

    Abstract translation: 描述了用于放置用于毛细管内部的材料测定的材料的站的自动测定系统和用于操纵毛细管的自动化夹具。 该系统包括分离和固定站，其中毛细管内部发生反应，并且检测到来自毛细血管反应的光摄取的检测器站。 来自毛细血管的光摄取可以显示为线图或类似于熟悉的Western凝胶印迹的假凝胶图像的列。 自动化控制系统具有用户界面，通过该界面，操作员可以选择运行协议并定义要在协议运行中使用的样本和试剂的位置。 在设置之后，控制系统将使自动化系统执行协议，然后以选定的显示格式显示结果。

    AUTOMATED MICRO-VOLUME ASSAY SYSTEM
    10.
    发明申请
    AUTOMATED MICRO-VOLUME ASSAY SYSTEM 审中-公开
    自动微量测定系统

    公开(公告)号：WO2006110725A2

    公开(公告)日：2006-10-19

    申请号：PCT/US2006/013447

    申请日：2006-04-10

    Applicant: CELL BIOSCIENCES, INC. ,  ROACH, David J ,  YANG, Tom W ,  O'NEILL, Roger A ,  LODER, JR., Robert T ,  VANDER HORN, Peter B

    Inventor： ROACH, David J ,  YANG, Tom W ,  O'NEILL, Roger A ,  LODER, JR., Robert T ,  VANDER HORN, Peter B

    IPC: A47J36/02

    CPC classification number: F16L41/00 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/1034 ,  G01N2035/1039 ,  G01N2035/1051 ,  G01N2035/1062 ,  Y10T137/0318 ,  Y10T137/85938 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/2575

    Abstract: An automated assay system is described with stations for placement of materials to be used in an assay of materials inside capillaries and an automated gripper for manipulating capillaries. The system includes a separation and immobilization station where reactions inside the capillaries take place and a detector station where photoemissions from the capillary reactions are detected. The photoemissions from the capillaries may be displayed as line graphs or in columns of a pseudo-gel image resembling the familiar Western gel blot. An automated control system has a user interface by which an operator can select a run protocol and define the locations of samples and reagents to be used in the protocol run. Following the setup the control system will cause the automated system to execute the protocol, then display the results in a selected display format.

    Abstract translation: 描述了用于放置用于毛细管内部的材料测定的材料的站的自动测定系统和用于操纵毛细管的自动化夹具。 该系统包括分离和固定站，其中毛细管内部发生反应，并且检测到来自毛细血管反应的光摄取的检测器站。 来自毛细血管的光摄取可以显示为线图或类似于熟悉的Western凝胶印迹的假凝胶图像的列。 自动化控制系统具有用户界面，通过该界面，操作员可以选择运行协议并定义要在协议运行中使用的样本和试剂的位置。 在设置之后，控制系统将使自动化系统执行协议，然后以选定的显示格式显示结果。

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