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1.发明申请GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES 审中-公开谷氨酰胺衍生物，其用途及其制备方法及制备谷氨酰胺衍生物的方法
公开(公告)号：WO2014168522A4
公开(公告)日：2015-01-22
申请号：PCT/RU2014000264
申请日：2014-04-10
IPC分类号： C07D401/06 , A61K31/34 , A61K31/381 , A61K31/415 , A61K31/421 , A61K31/427 , A61K31/45 , A61P11/02 , A61P31/16 , C07D401/14 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D471/04
CPC分类号： C07D401/06 , C07D401/14 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D453/02 , C07D471/04 , C07D487/04
摘要： The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or pharmaceutically acceptable salts thereof, the use thereof as agents for treating upper respiratory tract diseases, pharmaceutical compositions containing glutarimide derivatives of general formula (I), and methods for producing glutarimide derivatives of general formula (I) by heating a dicarboxylic acid monoamide of general formula (II) with a dehydrating agent.
摘要翻译： 本发明涉及通式（I）的新型生物活性戊二酰亚胺衍生物或其药学上可接受的盐，其作为治疗上呼吸道疾病的药物的用途，含有通式（I）的戊二酰亚胺衍生物的药物组合物及其制备方法 通式（I）的戊二酰亚胺衍生物通过用脱水剂加热通式（II）的二羧酸单酰胺。
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2.发明申请GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES 审中-公开谷癸酰胺衍生物，其用途，基于其的药物组合物以及用于制备谷氨酰胺衍生物的方法
公开(公告)号：WO2014168522A9
公开(公告)日：2014-12-04
申请号：PCT/RU2014000264
申请日：2014-04-10
IPC分类号： C07D401/06 , A61K31/34 , A61K31/381 , A61K31/415 , A61K31/421 , A61K31/427 , A61K31/45 , A61P11/02 , A61P31/16 , C07D401/14 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D471/04
CPC分类号： C07D401/06 , C07D401/14 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D453/02 , C07D471/04 , C07D487/04
摘要： The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or pharmaceutically acceptable salts thereof, the use thereof as agents for treating upper respiratory tract diseases, pharmaceutical compositions containing glutarimide derivatives of general formula (I), and methods for producing glutarimide derivatives of general formula (I) by heating a dicarboxylic acid monoamide of general formula (II) with a dehydrating agent.
摘要翻译： 本发明涉及通式（I）的新型生物活性戊二酰亚胺衍生物或其药学上可接受的盐，其作为上呼吸道疾病治疗剂的用途，含有通式（I）的戊二酰亚胺衍生物的药物组合物，以及生产 通式（I）的戊二酰亚胺衍生物通过用脱水剂加热通式（II）的二羧酸单酰胺来制备。
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3.发明申请DICARBOXYLIC ACID BISAMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING DICARBOXYLIC ACID BISAMIDE DERIVATIVES 审中-公开二羧酸二异氰酸酯衍生物及其用途及其制备方法及其制备方法用于制备二羧酸二异氰酸酯衍生物
公开(公告)号：WO2014168523A4
公开(公告)日：2015-01-08
申请号：PCT/RU2014000265
申请日：2014-04-10
IPC分类号： C07D403/12 , A61K31/4178 , A61K31/4184 , A61K31/427 , A61K31/428 , A61P1/16 , A61P3/10 , A61P7/06 , A61P9/00 , A61P25/28 , A61P25/32 , A61P31/00 , A61P31/12 , A61P35/00 , A61P39/06 , A61P43/00 , C07D417/12
CPC分类号： C07D403/12 , C07D233/64 , C07D235/14 , C07D277/28 , C07D277/64 , C07D417/12
摘要： The present invention relates to novel biologically active compounds being dicarboxylic acid bisamide derivatives of general formula (I), or pharmaceutically acceptable salts thereof, which are capable of complexing or chelating metal ions, and the use thereof as an agent for the prevention and/or treatment of cardiovascular, viral, cancerous, neurodegenerative and inflammatory diseases, diabetes and age-related diseases as well as diseases caused by microbial toxins, and also alcoholism, alcoholic cirrhosis, anaemia, porphyria cutanea tarda and transition metal salt poisoning. The present invention also relates to novel methods for producing dicarboxylic acid bisamide derivatives of general formula (I).
摘要翻译： 本发明涉及新颖的生物活性化合物，其是能够络合或螯合金属离子的通式（I）的二羧酸双酰胺衍生物或其药学上可接受的盐，以及其用作预防和/或 治疗心血管病毒，病毒性，癌性，神经退行性和炎性疾病，糖尿病和年龄相关疾病以及由微生物毒素引起的疾病，以及酒精中毒，酒精性肝硬化，贫血，phy，卟啉和过渡金属盐中毒。 本发明还涉及制备通式（I）的二羧酸双酰胺衍生物的新方法。
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4.发明申请
公开(公告)号：WO2013073998A3
公开(公告)日：2013-08-08
申请号：PCT/RU2012000939
申请日：2012-11-15
发明人： NEBOLSIN VLADIMIR EVGENIEVICH , ZHELTUKHINA GALINA ALEXANDROVNA , OKOROCHENKOV SERGEI ALEXANDROVICH
IPC分类号： C07K14/795 , A61K31/555 , A61K38/41 , A61P31/22 , C07F15/02
CPC分类号： C07F15/025 , A61K31/555 , A61K38/00 , C07D487/22 , C07K5/06069 , C07K5/06095 , C07K5/06104 , C07K14/795
摘要： The invention relates to novel derivatives of hemin of general formula (I) and to the production and use thereof as antibacterial and/or antiviral agents, including in the formulation of pharmaceutical compositions. Advantages of the novel antibacterial and antiviral agents on the basis of derivatives of hemin include the biocompatibility and biodegradability thereof and the high degree of effectiveness thereof against resistant bacteria and widespread viruses which are dangerous to humans, and the lack of toxicity.
摘要翻译： 本发明涉及通式（I）的氯化血红素的新衍生物及其作为抗菌和/或抗病毒剂的制备和用途，包括在药物组合物的制剂中。 基于氯化血红素衍生物的新型抗细菌和抗病毒剂的优点包括其生物相容性和生物可降解性及其对付对人有危险的耐药细菌和广泛病毒的高度有效性以及缺乏毒性。
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