公开(公告)号：WO2011049309A3

公开(公告)日：2011-10-13

申请号：PCT/KR2010006910

申请日：2010-10-08

申请人： YUNGJIN PHARM CO LTD ,  OH DONG-JOON ,  KIM BYOUNG-KI ,  MOON BYUNG-KWAN ,  YOO JI-SEOK ,  SHIN DAE-HEE ,  RYOO BYUNG-HWAN

发明人： OH DONG-JOON ,  KIM BYOUNG-KI ,  MOON BYUNG-KWAN ,  YOO JI-SEOK ,  SHIN DAE-HEE ,  RYOO BYUNG-HWAN

IPC分类号： A61K9/22 ,  A61K9/20 ,  A61K47/30 ,  A61K47/38

CPC分类号： A61K9/5084

摘要： The present invention relates to a pharmaceutical composition with both immediate and extended release characteristics, and more specifically, to a pharmaceutical composition comprising: an extended release portion comprising a pharmaceutically active ingredient, a release control material and a pharmaceutically acceptable carrier wherein a water-insoluble polymer is coated on the surface; and an immediate release portion comprising a pharmaceutically active ingredient and a pharmaceutically acceptable carrier. The pharmaceutical composition of the present invention shows independent release characteristics of an immediate release portion and an extended release portion by coating a water-insoluble polymer on the surface of the extended release portion, using a release control material and a pharmaceutically acceptable carrier to separate the extended release portion from the immediate release portion, and which can be prepared by a relatively simple process without limitation to the content or type of pharmaceutical active ingredient.

摘要翻译： 本发明涉及具有立即释放特征和延长释放特征的药物组合物，更具体地涉及药物组合物，其包含：包含药物活性成分，释放控制物质和药学上可接受的载体的缓释部分，其中水不溶性 聚合物被涂覆在表面上; 以及包含药物活性成分和药学上可接受的载体的速释部分。 本发明的药物组合物通过使用释放控制材料和药学上可接受的载体将水不溶性聚合物涂布在缓释部分的表面上而显示立即释放部分和缓释部分的独立释放特征， 缓释部分与速释部分组合，并且可以通过相对简单的方法制备，而不限于药物活性成分的含量或类型。