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    NEW ANTIBACTERIAL AGENT BASED ON FATTY ACID ESTERS OF HYDROXY CARBOXYLIC ACIDS
    1.
    发明申请
    NEW ANTIBACTERIAL AGENT BASED ON FATTY ACID ESTERS OF HYDROXY CARBOXYLIC ACIDS 审中-公开
    基于羟基羧酸的脂肪酸的新型抗菌剂

    公开(公告)号：WO2009037269A1

    公开(公告)日：2009-03-26

    申请号：PCT/EP2008/062340

    申请日：2008-09-17

    Applicant: PURAC BIOCHEM BV ,  KREMER, Diderik Reinder ,  RAMIREZ, Aldana Mariel ,  OTTO, Roel

    Inventor： KREMER, Diderik Reinder ,  RAMIREZ, Aldana Mariel ,  OTTO, Roel

    IPC: A01N37/36 ,  A01N63/02 ,  A01N63/00 ,  A01N37/46 ,  A01N43/16 ,  A01P1/00

    CPC classification number: A01N37/36 ,  A01N37/46 ,  A01N43/16 ,  A01N63/00 ,  A01N63/02 ,  A01N2300/00

    Abstract: The present invention relates to an antibacterial composition based on a combination of fatty acid ester of fatty acid and hydroxy carboxylic acid with an antibacterial agent selected from polylysine, protamine, their salts and mixtures hereof. The hydroxy carboxySic acid may be present as acid in its free form, in its salt form and/or in its ester form. The present invention further is directed to the use of said composition as antibacterial agent against gram-negative bacteria in various products, applications and methods. Furthermore, the present invention is related to products comprising said antibacterial agent.

    Abstract translation: 本发明涉及一种基于脂肪酸脂肪酸酯与羟基羧酸与选自聚赖氨酸，鱼精蛋白，它们的盐及其混合物的抗菌剂的组合的抗菌组合物。 羟基羧酸可以其游离形式的酸形式存在，其盐形式和/或其酯形式存在。 本发明还涉及在各种产品，应用和方法中所述组合物作为抗菌剂对革兰氏阴性细菌的用途。 此外，本发明涉及包含所述抗菌剂的产品。

    PREPARATION OF LACTIC ACID FROM A PENTOSE-CONTAINING SUBSTRATE
    2.
    发明申请
    PREPARATION OF LACTIC ACID FROM A PENTOSE-CONTAINING SUBSTRATE 审中-公开
    从含有戊糖的基质制备乳酸

    公开(公告)号：WO2004063382A3

    公开(公告)日：2004-09-23

    申请号：PCT/EP2004050013

    申请日：2004-01-12

    Applicant: PURAC BIOCHEM BV ,  OTTO ROEL

    Inventor： OTTO ROEL

    IPC: C12P7/56

    CPC classification number: C12P7/56

    Abstract: This invention relates to the production of lactic acid and/or lactate from pentose-containing substrate, particularly from xylose-containing substrate Currently, lactic acid is commercially produced from glucose, starch, liquefied starch or sucrose. At present, these substrates are the most important contributor to the manufacturing cost price of lactic acid. Lignocellulosic biomass offers a cost attractive alternative as a substrate for the biological production of lactic acid because it is readily available, has no competing food value, and is less expensive than either starch or sucrose. We have found that moderately thermophilic Bacillus species are able to ferment pentoses, more specifically xylose to enantiomerically pure lactic acid and/or lactate. Said conversion of pentoses leads to virtually only C3 compounds, i.e. said conversion runs via a homofermentive pathway, which C3 compounds can be recovered as lactic acid and/or lactate.

    Abstract translation: 本发明涉及由含有戊糖的底物，特别是从含木糖的底物生产乳酸和/或乳酸。目前，乳酸由葡萄糖，淀粉，液化淀粉或蔗糖商业生产。 目前，这些基材是乳酸生产成本价格最重要的因素。 木质纤维素生物质作为乳酸生物生产的底物提供了成本有吸引力的替代物，因为它容易获得，没有竞争性的食物价值，并且比淀粉或蔗糖便宜。 我们发现中等嗜热芽孢杆菌种能够将戊糖发酵，更特别是木糖转化成对映体纯的乳酸和/或乳酸。 所述戊糖转化实际上仅导致C3化合物，即所述转化通过同质发光途径进行，所述C3化合物可作为乳酸和/或乳酸回收。

    PREPARATION OF LACTIC ACID FROM A PENTOSE-CONTAINING SUBSTRATE
    3.
    发明申请
    PREPARATION OF LACTIC ACID FROM A PENTOSE-CONTAINING SUBSTRATE 审中-公开
    含有含PENTOSE的底物制备乳酸

    公开(公告)号：WO2004063382A2

    公开(公告)日：2004-07-29

    申请号：PCT/EP2004/050013

    申请日：2004-01-12

    Applicant: PURAC BIOCHEM B.V. ,  OTTO, Roel

    Inventor： OTTO, Roel

    IPC: C12P

    CPC classification number: C12P7/56

    Abstract: This invention relates to the production of lactic acid and/or lactate from pentose-containing substrate, particularly from xylose-containing substrate Currently, lactic acid is commercially produced from glucose, starch, liquefied starch or sucrose. At present, these substrates are the most important contributor to the manufacturing cost price of lactic acid. Lignocellulosic biomass offers a cost attractive alternative as a substrate for the biological production of lactic acid because it is readily available, has no competing food value, and is less expensive than either starch or sucrose. We have found that moderately thermophilic Bacillus species are able to ferment pentoses, more specifically xylose to enantiomerically pure lactic acid and/or lactate. Said conversion of pentoses leads to virtually only C3 compounds, i.e. said conversion runs via a homofermentive pathway, which C3 compounds can be recovered as lactic acid and/or lactate.

    Abstract translation: 本发明涉及从含戊糖的底物，特别是含木糖的底物生产乳酸和/或乳酸。目前，乳酸是由葡萄糖，淀粉，液化淀粉或蔗糖商业生产的。 目前，这些底物是乳酸制造成本价格最重要的贡献者。 木质纤维素生物质提供了成本有吸引力的替代物作为用于生物生产乳酸的底物，因为其易于获得，没有竞争的食物价值，并且比淀粉或蔗糖便宜。 我们已经发现中度嗜热芽孢杆菌种能够将戊糖发酵，更具体地说是将木糖发酵成对映体纯的乳酸和/或乳酸盐。 戊糖的所述转化仅导致C3化合物，即所述转化通过同型发酵途径进行，其中C3化合物可作为乳酸和/或乳酸回收。

    METHOD FOR THE PRODUCTION OF LACTIC ACID OR A SALT THEREOF BY SIMULTANEOUS SACCHARIFICATION AND FERMENTATION OF STARCH
    4.
    发明申请
    METHOD FOR THE PRODUCTION OF LACTIC ACID OR A SALT THEREOF BY SIMULTANEOUS SACCHARIFICATION AND FERMENTATION OF STARCH 审中-公开
    通过同时分离和发酵淀粉生产柠檬酸或其盐的方法

    公开(公告)号：WO2003095659A1

    公开(公告)日：2003-11-20

    申请号：PCT/EP2003/050159

    申请日：2003-05-13

    Applicant: PURAC BIOCHEM B.V. ,  OTTO, Roel

    Inventor： OTTO, Roel

    IPC: C12P7/56

    CPC classification number: C12R1/07 ,  C12P7/56

    Abstract: The present invention pertains to a method for the production of lactic acid or a salt thereof wherein starch is subjected to a process of simultaneous saccharification and fermentation, the method comprising saccharifying starch in a medium comprising at least a glucoamylase and simultaneously fermenting the starch using a microorganism, and optionally isolating lactic acid from the medium, characterized in that a moderately thermophilic lactic acid-producing microorganism is used. The invention further relates to a method of performing said process in the presence of a moderately thermophilic lactic acid producing microorganism, which has been adapted to have its maximum performance at the working pH.

    Abstract translation: 本发明涉及生产乳酸或其盐的方法，其中淀粉经受同时糖化和发酵的方法，所述方法包括在包含至少一种葡糖淀粉酶的培养基中糖化淀粉并同时使用 微生物和任选地从培养基中分离乳酸，其特征在于使用中等嗜热乳酸生产微生物。 本发明还涉及一种在中等嗜热乳酸生产微生物存在下进行所述方法的方法，其适于在工作pH下具有其最大性能。

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