公开(公告)号：WO2011008415A3

公开(公告)日：2011-04-14

申请号：PCT/US2010039229

申请日：2010-06-18

Applicant: VENTANA MED SYST INC ,  LEMME CHARLES D ,  WARD GLEN ,  KRAM BRIAN H ,  RICHARDS WILLIAM L

Inventor： LEMME CHARLES D ,  WARD GLEN ,  KRAM BRIAN H ,  RICHARDS WILLIAM L

IPC: G01N35/00 ,  G01N1/28

CPC classification number: G01N1/312 ,  G02B21/34

Abstract: A cover tile/substrate construct that includes a cover tile having an upper surface, an opposing lower surface, a proximal edge, a distal edge, and a longitudinal direction extending from the proximal edge to the distal edge, wherein the lower surface defines a three-dimensional surface that includes a protrusion that extends in the longitudinal direction; a substantially planar substrate having an upper surface and an opposing lower surface; and wherein the cover tile is juxtaposed over the substrate so that the lower surface of the cover tile and the upper surface of the substrate together define a wedge-shaped capillary fluid flow gap and the longitudinally extended protrusion of the lower surface of the cover tile protrudes towards the upper surface of the substrate.

Abstract translation: 包括具有上表面，相对的下表面，近侧边缘，远侧边缘和从近侧边缘延伸到远侧边缘的纵向方向的覆盖瓦片的覆盖瓦片/基底构造，其中下表面限定三个 所述三维表面包括在所述纵向方向上延伸的突起; 基本上平面的基底，其具有上表面和相对的下表面; 并且其中所述盖瓦并置在所述基板上，使得所述盖瓦的下表面和所述基板的上表面一起限定楔形毛细流体流动间隙，并且所述盖瓦的下表面的纵向延伸突出部突出 朝向衬底的上表面。

公开(公告)号：WO2010074917A1

公开(公告)日：2010-07-01

申请号：PCT/US2009/066637

申请日：2009-12-03

Applicant: VENTANA MEDICAL SYSTEMS, INC. ,  JACKSON, Merrill ,  CAMPBELL, Devon, C. ,  RICHARDS, William, L.

Inventor： JACKSON, Merrill ,  CAMPBELL, Devon, C. ,  RICHARDS, William, L.

IPC: G02B21/34 ,  G01N1/28

CPC classification number: G01N1/44 ,  G02B21/34

Abstract: This disclosure relates to apparatus for and methods of drying microscope slides. Some apparatus are microscope-slide dryers comprising a jet-pump body having a first side defining a flow channel and an exhaust port, and a second side defining a vacuum channel, an exhaust region and a heat-transfer surface. The exhaust port can fluidly couple the flow channel and the exhaust region. A top member can adjoin the first side. A flow of gas can be passed through the flow channel for inducing a low pressure in a first region at least partially defined by a second side of the jet-pump body. The jet-pump body can be heated. A difference in pressure can urge a slide against the jet-pump body. A portion of the flow can be directed over the slide.

Abstract translation: 本公开涉及显微镜载玻片的装置和干燥方法。 一些装置是显微镜载玻片干燥器，其包括具有限定流路和排气口的第一侧的喷射泵体，以及限定真空通道的第二侧，排气区域和传热表面。 排气口可以流体地联接流动通道和排气区域。 顶部成员可以与第一侧相邻。 气流可以通过流动通道，用于在至少部分地由喷射泵体的第二侧限定的第一区域中引起低压。 喷射泵体可以加热。 压力差可以促使对喷射泵体的滑动。 流动的一部分可以被引导到载玻片上。

公开(公告)号：WO1991013335A1

公开(公告)日：1991-09-05

申请号：PCT/US1991001149

申请日：1991-02-28

Applicant: IMMUNODIAGNOSTICS, INC. ,  COPELAND, Keith, G. ,  GROGAN, Thomas, M. ,  HASSEN, Charles ,  HUMPHREYS, William, Ross ,  LEMME, Charles, E. ,  MILLER, Phillip, C. ,  RICHARDS, William, L. ,  SHOWALTER, Wayne, A.

Inventor： IMMUNODIAGNOSTICS, INC.

IPC: G01N01/00

CPC classification number: G01N35/10 ,  B01F5/0057 ,  B01F13/0059 ,  B01F13/0272 ,  B01F2215/0037 ,  G01N1/312 ,  G01N35/025 ,  G01N2001/317 ,  G01N2035/00079 ,  G01N2035/00386 ,  G01N2035/00544 ,  G01N2035/00752

Abstract: An automated immunostaining apparatus having a reagent application zone and a reagent supply zone. The apparatus has a carousel slide support (24) supporting a plurality of slide supports (26) thereon, and drive means (48) engaging the carousel slide support (24) for consecutively positioning each of a plurality of slide supports (26) in the reagent application zone. The apparatus also has a carousel reagent support (10) having a plurality of reagent container supports (11) thereon, and drive means (14) engaging the carousel for rotating the carousel and positioning a preselected reagent container support (11) in the reagent supply zone. The apparatus also has a reagent delivery actuator means (18) positioned for engaging a reagent container (12) positioned on a container support (11) in the reagent delivery zone and initiating reagent delivery from the reagent container (12) to a slide supported on a slide support (26) in the reagent receiving zone.

Abstract translation: 一种具有试剂施用区和试剂供应区的自动免疫染色装置。 该装置具有支撑其上的多个滑动支撑件（26）的转盘滑​​动支撑件（24）和与圆盘传送带滑动支架（24）接合的驱动装置（48），用于将多个滑动支架（26）中的每一个连续地定位在 试剂应用区。 该装置还具有在其上具有多个试剂容器支架（11）的转盘试剂支架（10）和与圆盘传送带接合的驱动装置（14），用于旋转圆盘传送带并将预先选定的试剂容器支架（11） 区。 该装置还具有定位用于接合位于试剂输送区域中的容器支架（11）上的试剂容器（12）的试剂输送致动器装置（18），并且启动试剂从试剂容器（12）输送至支撑在 在试剂接收区中的滑动支架（26）。

公开(公告)号：WO2011139978A1

公开(公告)日：2011-11-10

申请号：PCT/US2011/034826

申请日：2011-05-02

Applicant: VENTANA MEDICAL SYSTEMS, INC. ,  LEMME, Charles ,  RICHARDS, William, L. ,  PANG, Lizhen ,  SHOWALTER, Wayne ,  REINHARDT, Kurt

Inventor： LEMME, Charles ,  RICHARDS, William, L. ,  PANG, Lizhen ,  SHOWALTER, Wayne ,  REINHARDT, Kurt

IPC: G01N1/31 ,  G01N1/30 ,  G01N35/10

CPC classification number: G01N1/312 ,  B01F11/0017 ,  B01F11/0071 ,  G01N2035/00346 ,  G01N2035/00465

Abstract: An automated cell staining apparatus comprises a translatable head and at least one mixing extension. The translatable head is positionable over a slide and has a lower surface. A portion of the lower surface is spaced apart from the slide by a first gap sufficiently small to allow a meniscus of liquid to form from liquid on the slide during translation of the slide. A mixing extension extends from the lower surface of the translatable head, defines a second gap smaller than the first gap between the mixing extension and the slide, and has a lateral dimension less than the width of the slide and sufficient to generate lateral movement in the liquid on the slide during translation of the head in a direction generally extending from the second gap to the first gap.

Abstract translation: 自动细胞染色装置包括可平移头部和至少一个混合延伸部。 可平移的头部可定位在滑动件上并具有较低的表面。 下表面的一部分与滑块隔开足够小的第一间隙，以允许在滑块平移期间液体从液体形成液面。 混合延伸部从可平移头部的下表面延伸，限定比混合延伸部和滑动件之间的第一间隙小的第二间隙，并且具有小于滑块宽度的横向尺寸，并足以在 在大致从第二间隙延伸到第一间隙的方向平移头部时，滑块上的液体。

公开(公告)号：WO2011008415A2

公开(公告)日：2011-01-20

申请号：PCT/US2010/039229

申请日：2010-06-18

Applicant: VENTANA MEDICAL SYSTEMS, INC. ,  LEMME, Charles, D. ,  WARD, Glen ,  KRAM, Brian, H. ,  RICHARDS, William, L.

Inventor： LEMME, Charles, D. ,  WARD, Glen ,  KRAM, Brian, H. ,  RICHARDS, William, L.

IPC: G01N35/00 ,  G01N1/28

CPC classification number: G01N1/312 ,  G02B21/34

Abstract: A cover tile/substrate construct that includes a cover tile having an upper surface, an opposing lower surface, a proximal edge, a distal edge, and a longitudinal direction extending from the proximal edge to the distal edge, wherein the lower surface defines a three-dimensional surface that includes a protrusion that extends in the longitudinal direction; a substantially planar substrate having an upper surface and an opposing lower surface; and wherein the cover tile is juxtaposed over the substrate so that the lower surface of the cover tile and the upper surface of the substrate together define a wedge-shaped capillary fluid flow gap and the longitudinally extended protrusion of the lower surface of the cover tile protrudes towards the upper surface of the substrate.

Abstract translation: 一种覆盖瓦片/基底构造，其包括具有上表面，相对的下表面，近端边缘，远侧边缘和从近端边缘延伸到远端边缘的纵向方向的覆盖瓦，其中下表面限定三 包括沿纵向方向延伸的突起的三维表面; 具有上表面和相对的下表面的基本平坦的基板; 并且其中所述覆盖瓦片并置在所述基板上，使得所述覆盖瓦片的下表面和所述基板的上表面一起限定楔形毛细流体流动间隙，并且所述盖板的下表面的纵向延伸的突出部突出 朝向基板的上表面。