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公开(公告)号:WO2022266758A1
公开(公告)日:2022-12-29
申请号:PCT/CA2022/051000
申请日:2022-06-22
发明人: KIZHAKKEDATHU, Jayachandran , SIREN, Erika , CHOY, Jonathan , LUO, Haiming , WITHERS, Stephen , DU, Caigan , ENNS, Winnie
摘要: Provided herein are compounds including a linear polyglycerol, a peptide tag, with either a linker-sugar-sialic acid moiety or a sulfate group, a preservation solutions including the compounds, methods for using the compounds or the preservation solutions to cell surface engineering (CSE) of a cell, a tissue, an organ for transplant, and methods for making the compounds. In particular, the CSE may recapitulate or rebuild glycocalyx on the luminal endothelial surface of an organ to limit immune rejection of the organ after transplant.
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公开(公告)号:WO2022187956A1
公开(公告)日:2022-09-15
申请号:PCT/CA2022/050346
申请日:2022-03-09
发明人: KIM, Woo Soo , KIM, Tae-ho
摘要: There is described a ventilator for providing breathable air to a patient. The ventilator includes an airbag defining a longitudinal axis, having a first end, a second end, and a foldable wall extending from the first end to the second end, and being movable from a decompressed state to a compressed state by moving the first end along the longitudinal axis relative to the second end. The wall has fold lines formed therein such that, during movement of the airbag from the decompressed state to the compressed state, the wall is folded along the fold lines. The fold lines define at least one polygonal surface portion of the wall. The ventilator further includes an actuator for driving compression and decompression of the airbag, and a controller for controlling the actuator.
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公开(公告)号:WO2019183724A9
公开(公告)日:2019-10-03
申请号:PCT/CA2019/050370
申请日:2019-03-26
申请人: TRIUMF, A JOINT VENTURE OF THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE UNIVERSITY OF BRITISH COLUMBIA, THE GOVERNORS OF THE UNIVERSITY OF CALGARY, CARLETON UNIVERSITY, UNIVERSITY OF GUELPH, MCMASTER UNIVERSITY, UNIVERSITY OF MANITOBA, UNIVERSITE DE MONTREAL, QUEEN'S UNIVERSITY, UNIVERSITY OF REGINA, SIMON FRASER UNIVERSITY, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, YORK UNIVERSITY, AND THE UNIVERSITY OF VICTORIA AND SUCH OTHER UNIVERSITIES WHO HAVE BECOME OR MAY BECOME FULL MEMBER UNIVERSITIES, ESTABLISHED PURSUANT TO A CONTRACT GOVERNED BY THE LAWS OF THE PROVINCE BRITISH COLUMBIA , ROBERTSON, Andrew Kyle Henderson
摘要: A method of separating actinium and/or radium from proton-irradiated thorium metal. The thorium metal is irradiated to produce isotopes including thorium, actinium and/or radium. The resultant product is dissolved in solution and a selective precipitant is used to precipitate a bulk portion of the thorium. The precipitated thorium can be recovered. Chromatography is carried out on the remaining solution to remove residual thorium and to separate the actinium from the radium.
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公开(公告)号:WO2019183724A1
公开(公告)日:2019-10-03
申请号:PCT/CA2019/050370
申请日:2019-03-26
申请人: TRIUMF, A JOINT VENTURE OF THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE UNIVERSITY OF BRITISH COLUMBIA, THE GOVERNORS OF THE UNIVERSITY OF CALGARY, CARLETON UNIVERSITY, UNIVERSITY OF GUELPH, MCMASTER UNIVERSITY, UNIVERSITY OF MANITOBA, UNIVERSITE DE MONTREAL, QUEEN'S UNIVERSITY, UNIVERSITY OF REGINA, SIMON FRASER UNIVERSITY, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, YORK UNIVERSITY, AND THE UNIVERSITY OF VICTORIA AND SUCH OTHER UNIVERSITIES WHO HAVE BECOME OR MAY BECOME FULL MEMBER UNIVERSITIES, ESTABLISHED PURSUANT TO A CONTRACT GOVERNED BY THE LAWS OF THE PROVINCE BRITISH COLUMBIA , ROBERTSON, Andrew Kyle Henderson
摘要: A method of separating actinium and/or radium from proton-irradiated thorium metal. The thorium metal is irradiated to produce isotopes including thorium, actinium and/or radium. The resultant product is dissolved in solution and a selective precipitant is used to precipitate a bulk portion of the thorium. The precipitated thorium can be recovered. Chromatography is carried out on the remaining solution to remove residual thorium and to separate the actinium from the radium.
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公开(公告)号:WO2018187864A1
公开(公告)日:2018-10-18
申请号:PCT/CA2018/050436
申请日:2018-04-10
发明人: HOLDCROFT, Steven , SKALSKI, Thomas J. G. , ADAMSKI, Michael , BRITTON, Benjamin , PECKHAM, Timothy J.
IPC分类号: C07C309/86 , B01D71/06 , B01J39/18 , C07D213/50 , C07D241/12 , C08F132/02
摘要: Described herein are anionic phenylene oligomers and polymers, and devices including these materials. The oligomers and polymers can be prepared in a convenient and well-controlled manner, and can be used in cation exchange 5 membranes. Also described is the controlled synthesis of anionic phenylene monomers and their use in synthesizing anionic oligomers and polymers, with precise control of the position and number of anionic groups.
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公开(公告)号:WO2018132908A1
公开(公告)日:2018-07-26
申请号:PCT/CA2018/050052
申请日:2018-01-17
发明人: GOLNARAGHI, Farid , SHOKOUFI, Majid
摘要: A diffuse-optical-spectroscopy system and method for scanning human tissue is provided. The system includes: (a) a handheld probe operable to emit electromagnetic radiation at one or more wavelengths corresponding to absorption associated with one or more human-tissue constituents, respectively, the handheld probe being operable to detect received electromagnetic radiation at each of the wavelengths; and (b) a processor operable to produce, in response to the received electromagnetic radiation, one or more cross-sectional images of the human tissue respectively associated with the wavelengths. The handheld probe includes first and second sources for emitting the electromagnetic radiation and one or more sensors for detecting the received electromagnetic radiation. The sensors are aligned along a first axis and face in an outward direction. The first and second sources are aligned along the first axis, face in the outward direction, and are disposed on either side of the sensors.
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公开(公告)号:WO2018023097A1
公开(公告)日:2018-02-01
申请号:PCT/US2017/044554
申请日:2017-07-29
发明人: WRIGHT, Andrew , BRITTON, Benjamin , HOLDCROFT, Steven , FAN, Jiantao , WEISSBACH, Thomas , PECKHAM, Timothy, James , WARD, Jonathan, William
IPC分类号: C07D233/64 , A61P31/00
摘要: Provided herein are imidazolium polymers having steric hindrance at the 4-position of the imidazole moieties in the polymeric chain. The sterically-protected, N-methylated imidazolium polymers exhibit hydroxide stability in concentrated caustic solutions at elevated temperatures, such as at 100 °C and higher.
摘要翻译: 本文提供了在聚合物链中的咪唑部分的4-位具有空间位阻的咪唑鎓聚合物。 空间保护的N-甲基化咪唑鎓聚合物在升高的温度下,例如在100℃和更高的温度下,在浓苛性碱溶液中表现出氢氧化物稳定性。 p>
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公开(公告)号:WO2018018161A1
公开(公告)日:2018-02-01
申请号:PCT/CA2017/050914
申请日:2017-07-28
摘要: A method of electrochemical deposition of a metallic material onto a substrate is provided. The method includes providing an alkaline solution of hydroxide ions, immersing a metallic material precursor and the substrate into the alkaline solution to form an electrochemical bath, and electrochemically depositing a textured layer of the metallic material onto the substrate. A method of electrochemical deposition of a textured nanoparticle is provided. The method includes providing an alkaline solution of hydroxide ions, immersing the metallic material into the alkaline solution to form an electrochemical bath, and precipitating the textured nanoparticles from the electrochemical bath. A method of electrochemical deposition of a metallic material onto a nanoparticle is provided. The method includes providing an alkaline solution of hydroxide ions, immersing the metallic material and the nanoparticle into the alkaline solution to form an electrochemical bath, and depositing a textured layer of the metallic material onto the nanoparticle.
摘要翻译: 提供了一种将金属材料电化学沉积到衬底上的方法。 该方法包括提供氢氧根离子的碱性溶液,将金属材料前体和基底浸入碱性溶液中以形成电化学浴,并且将金属材料的织构化层电化学沉积到基底上。 提供了一种电化学沉积纹理纳米颗粒的方法。 该方法包括提供氢氧根离子的碱性溶液,将金属材料浸入碱性溶液中以形成电化学浴,并从电化学浴中沉淀出具有纹理的纳米颗粒。 提供了一种将金属材料电化学沉积到纳米粒子上的方法。 该方法包括提供氢氧根离子的碱性溶液,将金属材料和纳米粒子浸入碱性溶液中以形成电化学浴,并将金属材料的织构层沉积到纳米粒子上。 p>
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公开(公告)号:WO2016187709A1
公开(公告)日:2016-12-01
申请号:PCT/CA2016/050584
申请日:2016-05-24
发明人: BAHRAMI, Majid , BAGHERI, Farshid
CPC分类号: E03B3/28 , B01D5/006 , B01D5/0075 , Y02A20/109
摘要: A hybrid atmospheric water generator (HAWG) utilizing, in certain embodiments, a core atmospheric water generator (105) and a preconditioning unit (110) to increase humidity of air prior to water condensation. The core atmospheric unit comprises a condensing unit (106) having a water condensing heat exchanger (107) coupled to source of cooling (109). The preconditioning unit (110) includes a heat exchanger (112) and a sorption unit (114) configured to store moisture for release when air is passed through or near the sorption unit (114). The heat exchanger (112) is used to increase the temperature of air moving into or through the preconditioning unit (110) in order to increase the amount of moisture the air is able to store. The preconditioning unit enables the generation of more water per energy unit expended and/or generating water from ambient air under conditions in which traditional atmospheric water generators cannot function.
摘要翻译: 在某些实施例中,利用核心大气水发生器(105)和预调节单元(110)来利用在水冷凝之前增加空气湿度的混合大气水发生器(HAWG)。 核心大气单元包括具有连接到冷却源(109)的水冷凝热交换器(107)的冷凝单元(106)。 预处理单元(110)包括热交换器(112)和吸附单元(114),吸附单元(114)被配置为当空气通过或接近吸附单元(114)时存储用于释放的水分。 热交换器(112)用于增加进入或经过预调节单元(110)的空气的温度,以增加空气能够储存的水分量。 预处理单元能够在传统的大气发生器不能起作用的条件下,从环境空气中消耗和/或产生水的能量单元产生更多的水。
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公开(公告)号:WO2015157848A1
公开(公告)日:2015-10-22
申请号:PCT/CA2015/000248
申请日:2015-04-15
发明人: HOLDCROFT, Steven , WRIGHT, Andrew
CPC分类号: C08G73/18 , B01J41/13 , C08J5/2256 , C08J2379/04 , C25B13/08 , H01M4/8668 , H01M8/103 , H01M2008/1095
摘要: Described herein are stable hydroxide ion-exchange polymers. The polymers include ionenes, which are polymers that contain ionic amines in the backbone. The polymers are alcohol-soluble and water-insoluble. The polymers have a water uptake and an ionic conductivity that are correlated to a degree of N-substitution. Methods of forming the polymers and membranes including the polymers are also provided. The polymers are suitable, for example, for use as ionomers in catalyst layers for fuel cells and electrolyzers.
摘要翻译: 本文描述的是稳定的氢氧根离子交换聚合物。 这些聚合物包括紫罗烯,它们是在骨架中含有离子胺的聚合物。 聚合物是醇溶性的和水不溶性的。 聚合物具有与N-取代度相关的吸水性和离子电导率。 还提供了形成聚合物和包括聚合物的膜的方法。 聚合物适用于例如用作燃料电池和电解器的催化剂层中的离聚物。
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