公开(公告)号：WO2019197986A1

公开(公告)日：2019-10-17

申请号：PCT/IB2019/052911

申请日：2019-04-09

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K31/728 ,  A61K31/737 ,  A61K35/644 ,  A61K36/886 ,  A61P1/02 ,  A61P1/04

Abstract: The present invention relates to an aqueous liquid composition or hydroalcoholic liquid comprising a mixture which comprises or, alternatively, consists of a combination of Aloe vera gel, hyaluronic acid and honey and, optionally, food and/or pharmaceutical grade additives and/or technological excipients; said composition being for use in the preventive and/or curative treatment of the symptoms and disorders associated with gastroesophageal reflux (GERD) and/or laryngopharyngeal reflux (RLF) and the disease caused thereby, for use as an adjuvant in the symptomatic treatment of gastroesophageal and/or laryngopharyngeal reflux disease, or for use in a preventive and/or curative treatment against: (i) lesions of the oral cavity and of the pharyngo-laryngo-esophageal tract; (ii) mucositis; and/or (iii) aphthae and/or aphthoid lesions.

公开(公告)号：WO2018069832A1

公开(公告)日：2018-04-19

申请号：PCT/IB2017/056254

申请日：2017-10-10

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea ,  SALA, Sara

IPC: A61K36/886 ,  A61K31/728 ,  A61K31/737 ,  A61K35/644 ,  A61P1/04

Abstract: The present invention relates to a liquid composition for use in the treatment of gastroesophageal reflux. The composition of the present invention comprises a mixture which comprises or, alternatively, consists of a combination of Aloe vera gel, hyaluronic acid and honey and, optionally, food or pharmaceutical grade additives and/or technological excipients. The composition of the present invention also relates to a medical device comprising a mixture which comprises or, alternatively, consists of a combination of Aloe vera gel, hyaluronic acid and honey and, optionally, food or pharmaceutical grade additives and/or technological excipients. Said composition or composition for a medical device being for use in the preventive and/or curative treatment of the symptoms associated with gastroesophageal reflux and the disease caused thereby, as well as for use in the preventive and/or curative treatment of gastroesophageal reflux disorders.

Abstract translation: 本发明涉及用于治疗胃食管反流的液体组合物。 本发明的组合物包含一种混合物，该混合物包含或者由芦荟凝胶，透明质酸和蜂蜜以及任选的食品或药物级添加剂和/或工艺赋形剂的组合组成的混合物。 本发明的组合物还涉及包含混合物的医疗装置，所述混合物包含芦荟凝胶，透明质酸和蜂蜜以及任选的食品或药物级添加剂的组合或者可选地由芦荟凝胶，透明质酸和蜂蜜的组合组成的混合物 和/或技术赋形剂。 所述用于医疗装置的组合物或组合物用于预防性和/或治疗性治疗与胃食管反流相关的症状和由此引起的疾病，以及用于预防和/或治疗胃食管反流病症。

公开(公告)号：WO2022157744A1

公开(公告)日：2022-07-28

申请号：PCT/IB2022/050633

申请日：2022-01-25

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K9/72 ,  A61K31/728 ,  A61K31/737 ,  A61M15/00

Abstract: The present invention relates to a composition in form of dry powder for oral inhalation comprising a hyaluronic acid and a chondroitin sulfate, or salts thereof, and to a kit comprising: a dry powder inhaler and a blister, wherein said blister comprises said composition in form of dry powder. Furthermore, the present invention relates to said composition or kit for use in the treatment of diseases and/or symptoms of the mucous membranes and/or of tissues of the oral cavity, of the upper and lower respiratory tract and/or of the oesophagus caused by gastric reflux on oesophageal and/or extraoesophageal regions or caused by bacterial or non-bacterial infections or caused by irritant factors such as smoke or pollution.

公开(公告)号：WO2022064411A1

公开(公告)日：2022-03-31

申请号：PCT/IB2021/058677

申请日：2021-09-23

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K36/03 ,  A61K36/05 ,  A61K31/737 ,  A61K31/728 ,  A61K9/08 ,  A61K9/28 ,  A61K33/08 ,  A61K33/12 ,  A61K33/14 ,  A61K35/644 ,  A61K36/886 ,  A61P1/02 ,  A61P1/04 ,  A61P1/08 ,  A61Q11/00

Abstract: The present invention relates to mixtures or compositions comprising a chondroitin sulfate of plant origin or an analogue thereof (algae extract) and to the use thereof in the preventive or curative treatment of diseases and symptoms caused by gastric reflux in the gastroesophageal tract or in extra-oesophageal regions, and ulcers, lacerations and/or inflammations of the mucous membranes or the lining tissues of the various anatomical regions present in the tract from the stomach to the oral cavity, also including the upper respiratory tract.

公开(公告)号：WO2022064406A1

公开(公告)日：2022-03-31

申请号：PCT/IB2021/058670

申请日：2021-09-23

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K31/737 ,  A61K31/728 ,  A61K36/03 ,  A61K36/05 ,  A61K9/08 ,  A61K9/28 ,  A61K33/08 ,  A61K33/12 ,  A61K33/14 ,  A61K35/644 ,  A61K36/886 ,  A61P1/02 ,  A61P1/04 ,  A61P1/08 ,  A61Q11/00

Abstract: The present invention relates to mixtures or compositions comprising a chondroitin sulfate of plant origin or an analogue thereof (algae extract) and to the use thereof in the preventive or curative treatment of diseases and symptoms caused by gastric reflux in the gastroesophageal tract or in extra-oesophageal regions, and ulcers, lacerations and/or inflammations of the mucous membranes or the lining tissues of the various anatomical regions present in the tract from the stomach to the oral cavity, also including the upper respiratory tract.

公开(公告)号：WO2019087105A1

公开(公告)日：2019-05-09

申请号：PCT/IB2018/058552

申请日：2018-10-31

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K9/20 ,  A61K47/36 ,  A61K31/728 ,  A61K31/737 ,  A61P1/04

CPC classification number: A61K9/0056 ,  A61K31/728 ,  A61K31/737 ,  A61K33/08 ,  A61K33/10 ,  A61K33/12 ,  A61K47/36 ,  A61P1/04 ,  A61K2300/00

Abstract: The present invention relates to a suckable and/or melt-in-mouth tablet based on hyaluronic chondroitin sulphate and/or salts thereof.

公开(公告)号：WO2022064415A1

公开(公告)日：2022-03-31

申请号：PCT/IB2021/058684

申请日：2021-09-23

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K36/03 ,  A61K36/05 ,  A61K31/737 ,  A61K31/728 ,  A61K9/08 ,  A61K9/28 ,  A61K33/08 ,  A61K33/12 ,  A61K33/14 ,  A61K35/644 ,  A61K36/886 ,  A61P1/02 ,  A61P1/04 ,  A61P1/08 ,  A61Q11/00

Abstract: The present invention relates to mixtures or compositions comprising a chondroitin sulfate of plant origin or an analogue thereof (algae extract) and to the use thereof in the preventive or curative treatment of diseases and symptoms caused by gastric reflux in the gastroesophageal tract or in extra-oesophageal regions, and ulcers, lacerations and/or inflammations of the mucous membranes or the lining tissues of the various anatomical regions present in the tract from the stomach to the oral cavity, also including the upper respiratory tract.

公开(公告)号：WO2019087100A1

公开(公告)日：2019-05-09

申请号：PCT/IB2018/058543

申请日：2018-10-31

Applicant: SOFAR SWISS SA

Inventor： BIFFI, Andrea

IPC: A61K9/00 ,  A61K31/728 ,  A61P1/04

CPC classification number: A61K9/0056 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/728 ,  A61K31/737 ,  A61K33/00 ,  A61K33/10 ,  A61K45/06 ,  A61K47/02 ,  A61K47/36 ,  A61P1/04 ,  A61K2300/00

Abstract: The present invention relates to a chewable and/or suckable and/or melt-in-mouth tablet based on hyaluronic acid and chondroitin sulphate and/or salts thereof.